Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Gang, Tu"'
m6A-TCPred: a web server to predict tissue-conserved human m6A sites using machine learning approach
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Background N6-methyladenosine (m6A) is the most prevalent post-transcriptional modification in eukaryotic cells that plays a crucial role in regulating various biological processes, and dysregulation of m6A status is involved in multiple hum
Externí odkaz:
https://doaj.org/article/cb68134299b14da8829ac6e1b076a9b8
Publikováno v:
World Journal of Surgical Oncology, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Background Pathological complete response (pCR) is the goal of neoadjuvant chemotherapy (NACT). We aimed to develop a nomogram to predict the probability of achieving pCR in estrogen receptor-positive (ER+), HER2-negative (HER2−) breast ca
Externí odkaz:
https://doaj.org/article/4eb54754a751436ea57d1cea74bdce85
Autor:
Siyang Wen, Yilu Qin, Rui Wang, Liping Yang, Huan Zeng, Pengpeng Zhu, Qiao Li, Yuxiang Qiu, Shanchun Chen, Yongcan Liu, Yixuan Hou, Xi Tang, Manran Liu, Gang Tu
Publikováno v:
Cell Death and Disease, Vol 12, Iss 5, Pp 1-14 (2021)
Abstract Tumor initiation, development, and relapse may be closely associated with cancer stem cells (CSCs). The complicated mechanisms underlying the maintenance of CSCs are keeping in illustration. Long noncoding RNAs (lncRNAs), due to their multif
Externí odkaz:
https://doaj.org/article/832b7f107682402fb03dea49bab8bf98
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-19 (2021)
Abstract Background Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, with poor prognosis and limited treatment options. Hypoxia is a key hallmark of TNBC. Metabolic adaptation promotes progression of TNBC cells th
Externí odkaz:
https://doaj.org/article/c0a5e1298c994fc1a51cc15c7f0871cb
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Breast cancer (BC) is the second leading cause of death among women and is highly heterogeneous. Three pyroptosis (PR) subtypes were identified in patients with BC from the Cancer Genome Atlas Database (TCGA) cohorts using 20 PR-related regulators, w
Externí odkaz:
https://doaj.org/article/c5726f9f04314a7a81111371240d532e
Publikováno v:
Frontiers in Climate, Vol 3 (2022)
Rice is the basic food for about 50% of the global population, and feeds two-thirds of the Chinese population. Under the influence of global change, extreme weather, and climate events increase in frequency, duration, and intensity, which affect food
Externí odkaz:
https://doaj.org/article/83219be1fc694aa7b510005009c9038a
Autor:
Pin-Jian Xiao, Jia-Cheng Zeng, Ping Lin, Dao-Bang Tang, En Yuan, Yong-Gang Tu, Qing-Feng Zhang, Ji-Guang Chen, Da-Yong Peng, Zhong-Ping Yin
Publikováno v:
Molecules, Vol 27, Iss 21, p 7583 (2022)
Chalcone-1-deoxynojirimycin heterozygote (DC-5), a novel compound which was designed and synthesized in our laboratory for diabetes treatment, showed an extremely strong in vitro inhibitory activity on α-glucosidase in our previous studies. In the c
Externí odkaz:
https://doaj.org/article/2d234016b2d144eb8133d9b541b24791
Autor:
Lei Lang, Yixuan Hou, Yanlin Chen, Gang Tu, Jing Tao, Dan Yang, Lei Xi, Lixin Fu, Kexin Sun, Jiali Yin, Rui Chen, Meixi Peng, Shuiqing Liu, Manran Liu
Publikováno v:
Cellular Physiology and Biochemistry, Vol 51, Iss 6, Pp 2972-2988 (2018)
Background/Aims: The ataxia-telangiectasia mutated (ATM) protein kinase is critical for the maintenance of genomic stability and acts as tumor suppressor. Although evidence shows that a DNA damage-independent ATM (oxidized ATM) may be involved in can
Externí odkaz:
https://doaj.org/article/476480ac2c9c4a2c881d1139a965da34
Autor:
Yu-an Qiu, Jianping Xiong, Qin Fu, Yun Dong, Manran Liu, Meixi Peng, Wenjian Jin, Lixia Zhou, Xue Xu, Xianming Huang, Airong Fu, Guohui Xu, Gang Tu, Tenghua Yu
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Hepatocellular carcinoma (HCC) is an aggressive malignancy with a poor prognosis. Effective biomarkers and specific therapeutic targets for HCC are therefore urgently needed. G protein-coupled estrogen receptor (GPER) plays a crucial role in numerous
Externí odkaz:
https://doaj.org/article/9e509921fcaa4422826a0b5a1f861bf5
Publikováno v:
Laws, Vol 10, Iss 2, p 25 (2021)
The Yangtze River Basin is the largest river basin in China and has the most complex trans-boundary problems. The water quality monitoring system of the provincial boundary sections in the basin is the typical go-to system to show the interaction bet
Externí odkaz:
https://doaj.org/article/e2fbc91d58e0411aaf87ebc1060e15ca