Výsledky vyhledávání - "Ganeshsingh A. Thakur"

AM841, a covalent cannabinoid ligand, powerfully slows gastrointestinal motility in normal and stressed mice in a peripherally restricted manner

Autor: Ganeshsingh A. Thakur, Alexandros Makriyannis, Keith A. Sharkey, Alex Straiker, Catherine M. Keenan, Mohammad Bashashati, Ken Mackie, Marsha R. Eno, JodiAnne T. Wood, Martin Storr, Jim Wager-Miller, Huang-Ming Hu, Spyridon P. Nikas

Publikováno v: British Journal of Pharmacology. 172:2406-2418

Background and Purpose Cannabinoid (CB) ligands have been demonstrated to have utility as novel therapeutic agents for the treatment of pain, metabolic conditions and gastrointestinal (GI) disorders. However, many of these ligands are centrally activ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0230a556852ffb7f874ec57ec3faeca8
https://doi.org/10.1111/bph.13069

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Abstract 602: The α7 nicotinic acetylcholine receptor silent agonist R-47 prevents and reverses paclitaxel-induced peripheral neuropathy without enhancing the proliferation of lung cancer cells or interfering with paclitaxel-induced antitumor activity

Autor: Ganeshsingh A. Thakur, David A. Gewirtz, M. Imad. Damaj, Wisam Toma, S. Lauren Kyte

Publikováno v: Cancer Research. 78:602-602

While cancer chemotherapy continues to significantly contribute to the number of cancer survivors, exposure to these drugs can often result in chemotherapy-induced peripheral neuropathy (CIPN), a consequence of peripheral nerve fiber dysfunction or d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3b89bd9baa125974b954ff54b8f97fa4
https://doi.org/10.1158/1538-7445.am2018-602

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Abstract 986: Targeting nicotinic acetylcholine receptors for the prevention and reversal of chemotherapy-induced peripheral neuropathy

Autor: Ganeshsingh A. Thakur, David A. Gewirtz, S. Lauren Kyte, M. Imad Damaj, Wisam Toma

Publikováno v: Cancer Research. 77:986-986

While chemotherapy has played a significant role in the survival of cancer patients, exposure to drugs such as the taxanes, platinum-based compounds, and bortezomib often results in chemotherapy-induced peripheral neuropathy (CIPN), a consequence of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::41cad1a5e4df9a0c40dcedffd2980af0
https://doi.org/10.1158/1538-7445.am2017-986

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Discriminative stimulus effects of methamphetamine and in vivo microdialysis in rats

Autor: Rajeev I. Desai, Carol A. Paronis, Ganeshsingh A. Thakur, Alexandros Makriyannis, Jack Bergman

Publikováno v: The FASEB Journal. 21

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::77124f1dcd036500b4ec72c73dd2eb34
https://doi.org/10.1096/fasebj.21.6.a776-b

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