Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Ganesh V Halade"'
Autor:
Armand O Brown, Beth Mann, Geli Gao, Jane S Hankins, Jessica Humann, Jonathan Giardina, Paola Faverio, Marcos I Restrepo, Ganesh V Halade, Eric M Mortensen, Merry L Lindsey, Martha Hanes, Kyle I Happel, Steve Nelson, Gregory J Bagby, Jose A Lorent, Pablo Cardinal, Rosario Granados, Andres Esteban, Claude J LeSaux, Elaine I Tuomanen, Carlos J Orihuela
Publikováno v:
PLoS Pathogens, Vol 10, Iss 9, p e1004383 (2014)
Hospitalization of the elderly for invasive pneumococcal disease is frequently accompanied by the occurrence of an adverse cardiac event; these are primarily new or worsened heart failure and cardiac arrhythmia. Herein, we describe previously unrecog
Externí odkaz:
https://doaj.org/article/9d373b6b3bb84d07a4fa366a25bcbb04
Autor:
Dae Hyun Lee, Vasundhara Kain, Da-Zhi Wang, Donald G. Rokosh, Sumanth D. Prabhu, Ganesh V. Halade
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 5, Iss , Pp 100046- (2023)
The lipid metabolizing enzyme 12/15 lipoxygenase (12/15LOX) induces proinflammatory responses that may increase cardiovascular and renal complications after cardiac insult. To define the role of 12/15LOX, 8–12-week-old male C57BL/6J wild-type (WT;
Externí odkaz:
https://doaj.org/article/0a6571f12cc748128174587bf67d2ff5
Autor:
Nicholas W. Carris, Rahul Mhaskar, Emily Coughlin, Easton Bracey, Srinivas M. Tipparaju, Ganesh V. Halade
Publikováno v:
BMC Cardiovascular Disorders, Vol 22, Iss 1, Pp 1-8 (2022)
Abstract Background Heart failure with preserved ejection fraction (HFpEF) is a syndrome with a heterogeneous cluster of causes, including non-resolving inflammation, endothelial dysfunction, and multi-organ defects. The present study’s objective w
Externí odkaz:
https://doaj.org/article/eec04d2235bc465cbd4bbdfeb9a70ec0
Autor:
Ganesh V. Halade, Dae Hyun Lee
Publikováno v:
EBioMedicine, Vol 79, Iss , Pp 103992- (2022)
Summary: Unresolved inflammation is a key mediator of advanced heart failure. Especially, damage, pathogen, and lifestyle-associated molecular patterns are the major factors in initiating baseline inflammatory diseases, particularly in cardiac pathol
Externí odkaz:
https://doaj.org/article/11f267fc14ff479583cd920d9079dd33
Autor:
Bochra Tourki, Vasundhara Kain, Amanda B. Pullen, Paul C. Norris, Nirav Patel, Pankaj Arora, Xavier Leroy, Charles N. Serhan, Ganesh V. Halade
Publikováno v:
Molecular Metabolism, Vol 31, Iss , Pp 138-149 (2020)
Objective: Recently, we observed that the specialized proresolving mediator (SPM) entity resolvin D1 activates lipoxin A4/formyl peptide receptor 2 (ALX/FPR2), which facilitates cardiac healing and persistent inflammation is a hallmark of impaired ca
Externí odkaz:
https://doaj.org/article/db743dad70734920abb663bad30b0a4d
Autor:
Ganesh V. Halade, Vasundhara Kain, Shahriare Hossain, Vibhu Parcha, Nita A. Limdi, Pankaj Arora
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 323(4)
Arachidonate 5-lipoxygenase (ALOX5)-derived leukotrienes are primary signals of leukocyte activation and inflammation in response to ischemic cardiac injury (MI; myocardial infarction). Using risk-free male C57BL/6J and ALOX5-null mice (8-12 wk), we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06e893ae8120c8e3c6d3d9080273a91f
https://pubmed.ncbi.nlm.nih.gov/36018758
https://pubmed.ncbi.nlm.nih.gov/36018758
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 8 (2020)
Background Leukocyte‐directed biosynthesis of specialized proresolving mediators (SPMs) orchestrates physiological inflammation after myocardial infarction. Deficiency of SPMs drives pathological and nonresolving inflammation, leading to heart fail
Externí odkaz:
https://doaj.org/article/4878bb256e604ba694ba4a1b15ab1538
Autor:
Anping Cai, Chrisly Dillon, William B. Hillegass, Mark Beasley, Brigitta C. Brott, Vera A. Bittner, Gilbert J. Perry, Ganesh V. Halade, Sumanth D. Prabhu, Nita A. Limdi
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 22 (2019)
Background Data on racial disparities in major adverse cardiovascular events (MACE) and major hemorrhage (HEM) after percutaneous coronary intervention are limited. Factors contributing to these disparities are unknown. Methods and Results PRiME‐GG
Externí odkaz:
https://doaj.org/article/fcc2fbdbac3b42e28c33cd2abaa61ee7
Autor:
Kah Yong Goh, Li He, Jiajia Song, Miki Jinno, Aaron J. Rogers, Palaniappan Sethu, Ganesh V. Halade, Namakkal Soorappan Rajasekaran, Xiaoguang Liu, Sumanth D. Prabhu, Victor Darley-Usmar, Adam R. Wende, Lufang Zhou
Publikováno v:
Redox Biology, Vol 21, Iss , Pp - (2019)
Increasing evidence indicates that mitochondrial-associated redox signaling contributes to the pathophysiology of heart failure (HF). The mitochondrial-targeted antioxidant, mitoquinone (MitoQ), is capable of modifying mitochondrial signaling and has
Externí odkaz:
https://doaj.org/article/11b98191ee0f49f0a8b90206fd0512fd
Publikováno v:
Am J Physiol Heart Circ Physiol
All fats are not created equal, and despite the extensive literature, the effect of fat intake is the most debated question in obesity, cardiovascular, and cardiorenal research. Cellular and molecular mechanisms underlying cardiac dysfunction and con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40cf2cb0d20499b4a80ee62bee50acc4
https://pubmed.ncbi.nlm.nih.gov/35333119
https://pubmed.ncbi.nlm.nih.gov/35333119