Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ganesh R Iyer"'
Autor:
William T. Prince, Vinay Kumar Venishetty, Jean Lecot, Kasra Shakeri‐Nejad, Cathy Gray, Amanda Taylor, Ganesh R. Iyer, Julia Zack
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 10, Pp 1758-1767 (2023)
Abstract Triclabendazole is an effective and well‐tolerated treatment for human fascioliasis. A placebo‐ and positive‐controlled, four‐sequence by four‐period crossover study was conducted in 45 healthy participants to assess the effect of
Externí odkaz:
https://doaj.org/article/64c515edc6524a60806e568d0973610f
Publikováno v:
Clinical Pharmacology in Drug Development. 12:333-342
Autor:
James E. Chastain, Upendra A. Argikar, Nagendra V. Chemuturi, Markus Walles, Gian Camenisch, Vito G. Sasseville, Jennifer L. Dumouchel, Mark Milton, Ganesh R. Iyer, Mithat Gunduz
Publikováno v:
Drug Metabolism and Disposition. 46:1670-1683
The eye is a complex organ with a series of anatomic barriers that provide protection from physical and chemical injury while maintaining homeostasis and function. The physiology of the eye is multifaceted, with dynamic flows and clearance mechanisms
Autor:
Kenneth N Sall, Ganesh R Iyer, Apinya Vutikullird, David Wirta, Abhijit Narvekar, Edward John Meier, Harvey Dubiner
Publikováno v:
Clinical Ophthalmology (Auckland, N.Z.)
Edward Meier,1 Abhijit Narvekar,2 Ganesh R Iyer,2 Harvey B DuBiner,3 Apinya Vutikullird,4 David Wirta,5 Kenneth Sall61Apex Eye, Mason, OH, 2Alcon Research Ltd., Fort Worth, TX, 3Clayton Eye Center, Morrow,GA, 4WCCT Global, Cypress, 5Eye Research Foun
Publikováno v:
Clinical pharmacology in drug development. 1(1)
The primary objective of this study is to characterize the pharmacokinetics of total (14)C concentrations following bilateral, topical ocular drops of (14)C-AL-8309B labeled either at the pyrimidyl ring (cohort A) position or at the imido-carbonyl ri
Autor:
Stephen R. Donahue, Karl Rickels, Michael Kauffman, Sanjay J. Mathew, Ganesh R. Iyer, Daniel L. Zimbroff, John F. Reinhard, Michael D. Banov, Edward C. Parsons, Scott Oshana
Publikováno v:
Journal of Clinical Psychopharmacology. 28:235-239
PRX-00023, a serotonin 1A receptor agonist, was designed to provide high potency and selectivity for its target. To assess the possible therapeutic utility in anxiety, a randomized, double-blind, placebo-controlled trial was conducted in 311 subjects
Publikováno v:
The Journal of Clinical Pharmacology. 47:817-824
PRX-00023 is a novel, nonazapirone 5-HT1A agonist in clinical development for treatment of affective disorders. The objectives of the initial clinical phase I studies (a single ascending dose study and multiple dose-ascending and high-dose titration
Publikováno v:
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. 31(4)
The primary objective of this study was to compare uptake and distribution of the commercially available formulation of 0.2% olopatadine and the newly developed 0.77% olopatadine hydrochloride ophthalmic solution formulation with improved solubility
Autor:
Savas Yavuzkurt, Ganesh R. Iyer
Publikováno v:
Annals of the New York Academy of Sciences. 934:265-272
A review of the past work done on free stream turbulence (FST) as applied to gas turbine heat transfer and its implications for future studies are presented. It is a comprehensive approach to the results of many individual studies in order to derive
Publikováno v:
Journal of Clinical Pharmacology. 42:428-436
The objective of this study was to compare the pharmacokinetics and safety of galantamine in subjects with hepatic impairment with those in healthy subjects. This was an open-label study in which a single oral 4-mg dose of galantamine was administere