Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ganesh R, Talekar"'
Autor:
Miyoung Lee, Jamie A. G. Hamilton, Ganesh R. Talekar, Anthony J. Ross, Langston Michael, Manali Rupji, Bhakti Dwivedi, Sunil S. Raikar, Jeremy Boss, Christopher D. Scharer, Douglas K. Graham, Deborah DeRyckere, Christopher C. Porter, Curtis J. Henry
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Obesity has been reported to promote tumourigenesis and chemoresistance but the underlying mechanisms are not completely understood. Here, the authors show that adipocytes induce Galectin-9 (GAL-9) expression in B-acute lymphoblastic leukaemia (B-ALL
Externí odkaz:
https://doaj.org/article/2dbae7c4d3ee43d79487bfe5ab1bc1e6
Autor:
Ganesh R. Talekar, Jamie Y. Story, James DeGregori, Raira S. Ank, Christopher C. Porter, Miyoung Lee, Curtis J. Henry, Jamie A.G. Hamilton, Andrew Fedanov, Talia Sisroe, Charles A. Dinarello, Dov B. Ballak, Rae Hunter, Sunil S. Raikar, Elan Z. Eisenmesser
Publikováno v:
Aging Cell
Aging‐associated declines in innate and adaptive immune responses are well documented and pose a risk for the growing aging population, which is predicted to comprise greater than 40 percent of the world's population by 2050. Efforts have been made
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c2bb5c15f8f6f5b58f8245d48954e12
http://europepmc.org/articles/PMC7884049
http://europepmc.org/articles/PMC7884049
Publikováno v:
Blood. 136:37-38
Background: Since the 1970's, obesity rates in children and adolescents have more than tripled (Ogden et al., 2006; Ogden et al., 2016) which parallels the rise in annual medical cost to treat obese pediatric patients in the United States which now e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bba200df0598139f6c1962064394eccc
https://doi.org/10.1182/blood-2020-143164
https://doi.org/10.1182/blood-2020-143164
Autor:
Miyoung, Lee, Jamie A G, Hamilton, Ganesh R, Talekar, Anthony J, Ross, Langston, Michael, Manali, Rupji, Bhakti, Dwivedi, Sunil S, Raikar, Jeremy, Boss, Christopher D, Scharer, Douglas K, Graham, Deborah, DeRyckere, Christopher C, Porter, Curtis J, Henry
Publikováno v:
Nature communications. 13(1)
The incidence of obesity is rising with greater than 40% of the world's population expected to be overweight or suffering from obesity by 2030. This is alarming because obesity increases mortality rates in patients with various cancer subtypes includ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d8dc77790e6ffeeca99f47696385ca82
https://pubmed.ncbi.nlm.nih.gov/35241678
https://pubmed.ncbi.nlm.nih.gov/35241678
Publikováno v:
Blood. 134:1468-1468
Background: The CDC reports that obesity rates in children and adolescents have more than tripled since the 1970's (Ogden et al., 2006; Ogden et al., 2016). Obese pediatric patients with B-cell acute lymphoblastic leukemia (B-ALL) have inferior overa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4639840e8bbd978ad09d14e19931281
https://doi.org/10.1182/blood-2019-126139
https://doi.org/10.1182/blood-2019-126139
Autor:
Xi Chen, Jamie Heimburg-Molinaro, Xuezheng Song, Yi Lasanajak, David F. Smith, Hai Yu, Ganesh R. Talekar, Richard D. Cummings, David A. Steinhauer, Konrad C. Bradley, Summer E. Galloway
Publikováno v:
Journal of Virology. 85:12387-12398
To examine the range of selective processes that potentially operate when poorly binding influenza viruses adapt to replicate more efficiently in alternative environments, we passaged a virus containing an attenuating mutation in the hemagglutinin (H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e5fd3bb9a9cd369c5a1f4ed6ac541e9
https://doi.org/10.1128/jvi.05570-11
https://doi.org/10.1128/jvi.05570-11
Autor:
Konrad C. Bradley, Zhu-Nan Li, William A. Langley, Ganesh R. Talekar, Summer E. Galloway, David A. Steinhauer
Publikováno v:
Vaccine. 28:6305-6313
The use of viral vectors as vaccine candidates has shown promise against a number of pathogens. However, preexisting immunity to these vectors is a concern that must be addressed when deciding which viruses are suitable for use. A number of propertie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15888ce76145964639b25f83b703a916
https://doi.org/10.1016/j.vaccine.2010.06.112
https://doi.org/10.1016/j.vaccine.2010.06.112
Autor:
William A. Langley, E. Varečková, Ru Pert J. Russell, Konrad C. Bradley, Summer E. Galloway, Sudha Thoennes, Sandra F. Cummings, David A. Steinhauer, Ganesh R. Talekar
Publikováno v:
Virology. 394:321-330
A panel of eight single amino acid deletion mutants was generated within the first 24 residues of the fusion peptide domain of the of the hemagglutinin (HA) of A/Aichi/2/68 influenza A virus (H3N2 subtype). The mutant HAs were analyzed for folding, c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7e7c5d3d474d3ae9ff2eb2e96059ebd
https://doi.org/10.1016/j.virol.2009.08.031
https://doi.org/10.1016/j.virol.2009.08.031
Autor:
David A. Ornelles, Charlie T. Garnett, Linda R. Gooding, Yu Zhang, Ganesh R. Talekar, Jeffrey A. Mahr, W Huang
Publikováno v:
Journal of Virology. 83:2417-2428
Although species C human adenoviruses establish persistent infections, the molecular details of this lifestyle remain poorly understood. We previously reported that adenovirus DNA is found in human mucosal T lymphocytes in a noninfectious form (C. T.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f46653e5eb857aec03fd95eafe79ec17
https://doi.org/10.1128/jvi.02392-08
https://doi.org/10.1128/jvi.02392-08
Autor:
U von Doblen, Emma Honkaniemi, M Engvall, Linda R. Gooding, David A. Ornelles, Ganesh R. Talekar, Erik Forestier, Gordana Bogdanovic, W Huang, Britt Gustafsson
Publikováno v:
British Journal of Cancer
Background: In search of a proposed viral aetiology of childhood acute lymphoblastic leukaemia (ALL), the common species C adenoviruses were analysed in Guthrie cards. Methods: Guthrie cards from 243 children who later developed ALL and from 486 matc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34c1ed24383d81e30e13e79a90c894e9
https://doi.org/10.1038/sj.bjc.6605581
https://doi.org/10.1038/sj.bjc.6605581