Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Ganesh Navinchandra Gote"'
Autor:
Shreyas Deshpande, Rashmi Talwar, Ganesh Navinchandra Gote, Jayasagar Gundu, Rupali Vyawahare, Shashikant Pawar, Akshaya Wagh, Talha Khan, Anil Kalia, Venkata P. Palle, Usha Dhayagude, M. K. Singh, Pradeep Patil, Ganesh Chaure, Praveen Kumar Gupta, Amit Das, Vijay Kanoje, Sharad Sharma, Vidya Ramdas, Vinod Patil, Rajesh Yeshodharan, Prashant B. Nigade, Dipak Modi, Dnyaneshwar Warude, Dilip Pandey, Jagadeesh Daler, Mahammad Azhar, Arun Nayak, Sneha Joshi, Sudipto Das, Rajender Kumar Kamboj, Javed S Shaikh, Maneesh Mehta, Deepak Sahebrao Walke, Rajesh V. Gupta, Himani Pareek, Kumar V S Nemmani, Parag Joshi, Mahip Verma, Vinod Mali, Laxmikant Datrange, Santosh Parkale, Rajesh Loriya, Vaibhav Kalhapure, Geetika Sharma, Ravindra R. Pal, Sagar Budhe, Gautam Agarwal, Sachin Suravase, Sagar Darekar, Mark G. Bock, Advait Arun Joshi, Moloy Banerjee, Smita Bhoskar, Amitesh Kishore, Dhananjay Bakhle
Publikováno v:
Journal of Medicinal Chemistry. 63:6107-6133
Voltage-gated sodium channel NaV1.7 is a genetically validated target for pain. Identification of NaV1.7 inhibitors with all of the desired properties to develop as an oral therapeutic for pain has been a major challenge. Herein, we report systematic
Autor:
Pratima Srivastava, Arnab Goswami, Amruta Dash, Deepak Sahebrao Walke, Gautam Agarwal, Dipak Modi, Moloy Banerjee, Rajender Kumar Kamboj, Rashmi Talwar, Hemant Kumar, Falguni Modi, Advait Arun Joshi, Aruna Sivaram, Venkata P. Palle, Vinod Patil, Lakshmi Narasimham, Vidya Ramdas, Ganesh Navinchandra Gote, Sharad Sharma, M. K. Singh, Sadanand Mallurwar, Prashant B. Nigade, Sandip Kuldharan, Prashant Borhade, Rajesh Loriya, Maneesh Mehta, Jayasagar Gundu, Apparao Bommakanti, Usha Dhayagude, Amit Kumar Das
Publikováno v:
Journal of Medicinal Chemistry. 62:10563-10582
The identification of a novel class of potent pan-genotypic NS5A inhibitors with good pharmacokinetic profile suitable for potential use in treating HCV infections is disclosed here. The present series of compounds are with less complex tricyclic cen