Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

Autor: Demontis, D, Walters, R, Martin, J, Mattheisen, M, Als, T, Agerbo, E, Baldursson, G, Belliveau, R, Bybjerg-Grauholm, J, Baekvad-Hansen, M, Cerrato, F, Chambert, K, Churchhouse, C, Dumont, A, Eriksson, N, Gandal, M, Goldstein, J, Grasby, K, Grove, J, Gudmundsson, O, Hansen, C, Hauberg, M, Hollegaard, M, Howrigan, D, Huang, H, Maller, J, Martin, A, Martin, N, Moran, J, Pallesen, J, Palmer, D, Pedersen, C, Pedersen, M, Poterba, T, Poulsen, J, Ripke, S, Robinson, E, Satterstrom, F, Stefansson, H, Stevens, C, Turley, P, Walters, G, Won, H, Wright, M, Andreassen, O, Asherson, P, Burton, C, Boomsma, D, Cormand, B, Dalsgaard, S, Franke, B, Gelernter, J, Geschwind, D, Hakonarson, H, Haavik, J, Kranzler, H, Kuntsi, J, Langley, K, Lesch, K, Middeldorp, C, Reif, A, Rohde, L, Roussos, P, Schachar, R, Sklar, P, Sonuga-Barke, E, Sullivan, P, Thapar, A, Tung, J, Waldman, I, Medland, S, Stefansson, K, Nordentoft, M, Hougaard, D, Werge, T, Mors, O, Mortensen, P, Daly, M, Faraone, S, Borglum, A, Neale, B, Albayrak, O, Anney, R, Arranz, M, Banaschewski, T, Bau, C, Biederman, J, Buitelaar, J, Casas, M, Charach, A, Crosbie, J, Dempfle, A, Doyle, A, Ebstein, R, Elia, J, Freitag, C, Focker, M, Gill, M, Grevet, E, Hawi, Z, Hebebrand, J, Herpertz-Dahlmann, B, Hervas, A, Hinney, A, Hohmann, S, Holmans, P, Hutz, M, Ickowitz, A, Johansson, S, Kent, L, Kittel-Schneider, S, Lambregts-Rommelse, N, Lehmkuhl, G, Loo, S, McGough, J, Meyer, J, Mick, E, Middletion, F, Miranda, A, Mota, N, Mulas, F, Mulligan, A, Nelson, F, Nguyen, T, Oades, R, O'Donovan, M, Owen, M, Palmason, H, Ramos-Quiroga, J, Renner, T, Ribases, M, Rietschel, M, Rivero, O, Romanos, J, Romanos, M, Rothenberger, A, Royers, H, Sanchez-Mora, C, Scherag, A, Schimmelmann, B, Schafer, H, Sergeant, J, Sinzig, J, Smalley, S, Steinhausen, H, Thompson, M, Todorov, A, Vasquez, A, Walitza, S, Wang, Y, Warnke, A, Williams, N, Witt, S, Yang, L, Zayats, T, Zhang-James, Y, Smith, G, Davies, G, Ehli, E, Evans, D, Fedko, I, Greven, C, Groen-Blokhuis, M, Guxens, M, Hammerschlag, A, Hartman, C, Heinrich, J, Hottenga, J, Hudziak, J, Jugessur, A, Kemp, J, Krapohl, E, Murcia, M, Myhre, R, Nolte, I, Nyholt, D, Ormel, J, Ouwens, K, Pappa, I, Pennell, C, Plomin, R, Ring, S, Standl, M, Stergiakouli, E, St Pourcain, B, Stoltenberg, C, Sunyer, J, Thiering, E, Tiemeier, H, Tiesler, C, Timpson, N, Trzaskowski, M, van der Most, P, Vilor-Tejedor, N, Wang, C, Whitehouse, A, Zhao, H, Agee, M, Alipanahi, B, Auton, A, Bell, R, Bryc, K, Elson, S, Fontanillas, P, Furlotte, N, Hinds, D, Hromatka, B, Huber, K, Kleinman, A, Litterman, N, McIntyre, M, Mountain, J, Northover, C, Pitts, S, Sathirapongsasuti, J, Sazonova, O, Shelton, J, Shringarpure, S, Tian, C, Vacic, V, Wilson, C, ADHD Working Grp Psychiat Genomics, Early Lifecourse Genetic, 23andMe Res Team

Publikováno v: Demontis, D, Walters, R K, Martin, J, Mattheisen, M, Als, T D, Agerbo, E, Baldursson, G, Belliveau, R, Bybjerg-Grauholm, J, Bækvad-Hansen, M, Cerrato, F, Chambert, K, Churchhouse, C, Dumont, A, Eriksson, N, Gandal, M, Goldstein, J I, Grasby, K L, Grove, J, Gudmundsson, O O, Hansen, C S, Hauberg, M E, Hollegaard, M V, Howrigan, D P, Huang, H, Maller, J B, Martin, A R, Moran, J, Martin, N G, Pallesen, J, Palmer, D S, Pedersen, C B, Pedersen, M G, Poterba, T, Poulsen, J B, Ripke, S, Robinson, E B, Satterstrom, F K, Stefansson, H, Stevens, C, Turley, P, Walters, G B, Won, H, Wright, M J, ADHD Working Group of the Psychiatric Genomics Consortium (PGC), Steinhausen, H-C E, Early Lifecourse & Genetic Epidemiology (EAGLE) Consortium, 23andMe Research Team, Andreassen, O A, Asherson, P, Burton, C L, Boomsma, D I, Cormand, B, Dalsgaard, S, Franke, B, Gelernter, J, Geschwind, D, Hakonarson, H, Haavik, J, Kranzler, H R, Kuntsi, J, Langley, K, Lesch, K-P, Middeldorp, C, Reif, A, Rohde, L A, Roussos, P, Schachar, R, Sklar, P, Sonuga-Barke, E J S, Sullivan, P F, Thapar, A, Tung, J Y, Waldman, I D, Medland, S E, Stefansson, K, Nordentoft, M, Hougaard, D M, Werge, T, Mors, O, Mortensen, P B, Daly, M J, Faraone, S V, Børglum, A D & Neale, B M 2019, ' Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder ', Nature Genetics, vol. 51, no. 1, pp. 63-75 . https://doi.org/10.1038/s41588-018-0269-7
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Nature genetics, vol 51, iss 1
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r-FISABIO. Repositorio Institucional de Producción Científica
Nature Genetics
23andMe Research Team, ADHD Working Group of the Psychiatric Genomics Consortium (PGC) & Early Lifecourse & Genetic Epidemiology (EAGLE) Consortium 2019, ' Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder ', Nature Genetics, vol. 51, no. 1, pp. 63-75 . https://doi.org/10.1038/s41588-018-0269-7, https://doi.org/10.1038/s41588-018-0269-7
Nature Genetics, 51(1), 63-75. Nature Publishing Group
Demontis, D, Walters, R K, Martin, J, Mattheisen, M, Als, T D, Agerbo, E, Baldursson, G S, Belliveau, R, Bybjerg-Grauholm, J, Bækvad-Hansen, M, Cerrato, F, Chambert, K, Churchhouse, C, Dumont, A, Eriksson, N, Gandal, M, Goldstein, J I, Grasby, K L, Grove, J, Gudmundsson, O O, Hansen, C S, Hauberg, M E, Hollegaard, M V, Howrigan, D P, Huang, H, Maller, J B, Martin, A R, Martin, N G, Moran, J, Pallesen, J, Palmer, D S, Pedersen, C B C, Pedersen, M G, Poterba, T, Poulsen, J B, Ripke, S, Robinson, E B, Satterstrom, F K, Stefansson, H, Stevens, C, Turley, P, Walters, G B, Won, H, Wright, M J, Albayrak, Ö, Nguyen, T T, Evans, D M, Groen-Blokhuis, M M, Hammerschlag, A R, Middeldorp, C, ADHD Working Group of the Psychiatric Genomics Consortium (PGC), Reif, A, Rohde, L A, Roussos, P, Schachar, R, Sonuga-Barke, E J S, Sullivan, P, Thapar, A, Tung, J Y, Waldman, I D, Medland, S E, Mors, O, Bo Mortensen, P, Daly, M J, Faraone, S V, Børglum, A D & Neale, B M 2019, ' Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder ', Nature Genetics, vol. 51, no. 1, pp. 63-75 . https://doi.org/10.1038/s41588-018-0269-7
ADHD Working Group of the Psychiatric Genomics Consortium (PGC) 2018, ' Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder ' Nature Genetics . https://doi.org/10.1038/s41588-018-0269-7
Nature Genetics, 51, 1, pp. 63-75
Demontis, D, Walters, R K, Martin, J, Mattheisen, M, Als, T D, Agerbo, E, Baldursson, G, Belliveau, R, Bybjerg-Grauholm, J, Bækvad-Hansen, M, Cerrato, F, Chambert, K, Churchhouse, C, Dumont, A, Eriksson, N, Gandal, M, Goldstein, J I, Grasby, K L, Grove, J, Gudmundsson, O O, Hansen, C S, Hauberg, M E, Hollegaard, M V, Howrigan, D P, Huang, H, Maller, J B, Martin, A R, Martin, N G, Moran, J, Pallesen, J, Palmer, D S, Pedersen, C B, Pedersen, M G, Poterba, T, Poulsen, J B, Ripke, S, Robinson, E B, Satterstrom, F K, Stefansson, H, Stevens, C, Turley, P, Walters, G B, Won, H, Wright, M J, ADHD Working Group of the Psychiatric Genomics Consortium (PGC), Early Lifecourse & Genetic Epidemiology (EAGLE) Consortium, 23andMe Research Team, Dalsgaard, S, Mors, O, Mortensen, P B & Børglum, A D 2019, ' Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder ', Nature Genetics, vol. 51, pp. 63–75 . https://doi.org/10.1038/s41588-018-0269-7
Nat Genet
Nature Genetics, 51, 63-75
Nature Genetics, 51(1), 63-+. Nature Publishing Group
Demontis, D, Walters, R K, Martin, J, Mattheisen, M, Als, T D, Agerbo, E, Baldursson, G, Belliveau, R, Bybjerg-grauholm, J, Bækvad-hansen, M, Cerrato, F, Chambert, K, Churchhouse, C, Dumont, A, Eriksson, N, Gandal, M, Goldstein, J I, Grasby, K L, Grove, J, Gudmundsson, O O, Hansen, C S, Hauberg, M E, Hollegaard, M V, Howrigan, D P, Huang, H, Maller, J B, Martin, A R, Martin, N G, Moran, J, Pallesen, J, Palmer, D S, Pedersen, C B, Pedersen, M G, Poterba, T, Poulsen, J B, Ripke, S, Robinson, E B, Satterstrom, F K, Stefansson, H, Stevens, C, Turley, P, Walters, G B, Won, H, Wright, M J, Andreassen, O A, Asherson, P, Burton, C L, Kuntsi, J, Sonuga-barke, E J S & Neale, B M & Plomin, R 2019, ' Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder ', Nature Genetics, vol. 51, no. 1, pp. 63-75 . https://doi.org/10.1038/s41588-018-0269-7
the 23 and Me Research Team, Demontis, D, Walters, R K, Martin, J, Mattheisen, M, Als, T D, Agerbo, E, Baldursson, G, Belliveau, R, Bybjerg-Grauholm, J, Bækvad-Hansen, M, Cerrato, F, Chambert, K, Churchhouse, C, Dumont, A, Eriksson, N, Gandal, M, Goldstein, J I, Grasby, K L, Grove, J, Gudmundsson, O O, Hansen, C S, Hauberg, M E, Hollegaard, M V, Howrigan, D P, Huang, H, Maller, J B, Martin, A R, Martin, N G, Moran, J, Pallesen, J, Palmer, D S, Pedersen, C B, Pedersen, M G, Poterba, T, Poulsen, J B, Ripke, S, Robinson, E B, Satterstrom, F K, Smith, G D, Davies, G E, Evans, D M, Kemp, J P, Ring, S, Stergiakouli, E, Pourcain, B S, Stoltenberg, C, Timpson, N J & Langley, K & Thapar, A & Medland, S E 2019, ' Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder ', Nature Genetics, vol. 51, no. 1, pp. 63-75 . https://doi.org/10.1038/s41588-018-0269-7
23andMe Research Team, ADHD Working Group of the Psychiatric Genomics Consortium (PGC) & Early Lifecourse & Genetic Epidemiology (EAGLE) Consortium 2018, ' Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder ' Nature Genetics . https://doi.org/10.1038/s41588-018-0269-7
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
Nature Genetics, 51(1). Nature Publishing Group

Attention deficit/hyperactivity disorder (ADHD) is a highly heritable childhood behavioral disorder affecting 5% of children and 2.5% of adults. Common genetic variants contribute substantially to ADHD susceptibility, but no variants have been robust

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce760c90c78b6a37ae310ef7de882004
https://vbn.aau.dk/da/publications/2ea2ba33-e51e-4b07-a628-232327647cdd

Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data.

Autor: Zhang MJ; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA. jinyezhang@hsph.harvard.edu.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA. jinyezhang@hsph.harvard.edu., Hou K; Bioinformatics Interdepartmental Program, University of California, Los Angeles, Los Angeles, CA, USA. houkc@ucla.edu.; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA. houkc@ucla.edu.; Department of Computational Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA. houkc@ucla.edu., Dey KK; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Sakaue S; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Data Sciences, Brigham and Women's Hospital, Boston, MA, USA.; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Division of Rheumatology, Inflammation, and Immunity, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Jagadeesh KA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Weinand K; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Data Sciences, Brigham and Women's Hospital, Boston, MA, USA.; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Division of Rheumatology, Inflammation, and Immunity, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Taychameekiatchai A; Department of Medicine and Liver Center, University of California, San Francisco, San Francisco, CA, USA.; Developmental and Stem Cell Biology Graduate Program, University of California, San Francisco, San Francisco, CA, USA., Rao P; Department of Medicine and Liver Center, University of California, San Francisco, San Francisco, CA, USA., Pisco AO; Chan Zuckerberg Biohub, San Francisco, CA, USA., Zou J; Chan Zuckerberg Biohub, San Francisco, CA, USA.; Department of Electrical Engineering, Stanford University, Palo Alto, CA, USA.; Department of Biomedical Data Science, Stanford University, Palo Alto, CA, USA., Wang B; Department of Medicine and Liver Center, University of California, San Francisco, San Francisco, CA, USA., Gandal M; Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.; Program in Neurobehavioral Genetics, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Raychaudhuri S; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Data Sciences, Brigham and Women's Hospital, Boston, MA, USA.; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Division of Rheumatology, Inflammation, and Immunity, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.; Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK., Pasaniuc B; Bioinformatics Interdepartmental Program, University of California, Los Angeles, Los Angeles, CA, USA. pasaniuc@ucla.edu.; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA. pasaniuc@ucla.edu.; Department of Computational Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA. pasaniuc@ucla.edu., Price AL; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA. aprice@hsph.harvard.edu.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA. aprice@hsph.harvard.edu.; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA. aprice@hsph.harvard.edu.

Publikováno v: Nature genetics [Nat Genet] 2022 Oct; Vol. 54 (10), pp. 1572-1580. Date of Electronic Publication: 2022 Sep 01.

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors.

Autor: Mullins N; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address: niamh.mullins@mssm.edu., Kang J; Division of Genetic Medicine, Department of Medicine, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tennessee., Campos AI; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia; School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia., Coleman JRI; National Institute for Health Research Maudsley Biomedical Research Centre at South London and Maudsley NHS Foundation Trust, London, United Kingdom; Social Genetic and Developmental Psychiatry Centre, King's College London, London, United Kingdom., Edwards AC; Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia., Galfalvy H; Department of Biostatistics, Columbia University, New York, New York; Department of Psychiatry, Columbia University, New York, New York., Levey DF; Department of Psychiatry, Veterans Affairs Connecticut Healthcare Center, West Haven, Connecticut; Division of Human Genetics, Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut., Lori A; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia., Shabalin A; Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, Utah., Starnawska A; Centre for Genomics and Personalized Medicine, Aarhus University, Aarhus, Denmark; Centre for Integrative Sequencing, Aarhus University, Aarhus, Denmark; Department of Biomedicine, Aarhus University, Aarhus, Denmark; Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus University, Aarhus, Denmark., Su MH; Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan., Watson HJ; School of Psychology, Curtin University, Perth, Western Australia, Australia; Division of Paediatrics, The University of Western Australia, Perth, Western Australia, Australia; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Adams M; Division of Psychiatry, University of Edinburgh, Edinburgh, United Kingdom., Awasthi S; Department of Psychiatry and Psychotherapy, Universitätsmedizin Berlin, Berlin, Germany., Gandal M; Department of Psychiatry and Biobehavioral Sciences, Semel Institute, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California., Hafferty JD; Division of Psychiatry, University of Edinburgh, Edinburgh, United Kingdom., Hishimoto A; Department of Psychiatry, Yokohama City University Graduate School of Medicine, Yokohama, Japan., Kim M; Department of Psychiatry and Biobehavioral Sciences, Semel Institute, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California., Okazaki S; Department of Psychiatry, Kobe University Graduate School of Medicine, Kobe, Japan., Otsuka I; Department of Psychiatry, Columbia University, New York, New York; Department of Psychiatry, Kobe University Graduate School of Medicine, Kobe, Japan., Ripke S; Department of Psychiatry and Psychotherapy, Universitätsmedizin Berlin, Berlin, Germany; Stanley Center for Psychiatric Research, Broad Institute, Cambridge, Massachusetts; Analytical and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts., Ware EB; Population Studies Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan; Survery Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan., Bergen AW; BioRealm, LLC, Walnut, California; Oregon Research Institute, Eugene, Oregon., Berrettini WH; Department of Psychiatry, Center for Neurobiology and Behavior, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Bohus M; Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Brandt H; Center for Eating Disorders at Sheppard Pratt, Baltimore, Maryland., Chang X; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Chen WJ; Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan; Department of Psychiatry, National Taiwan University Hospital, Taipei, Taiwan; Center for Neuropsychiatric Research, National Health Research Institutes, Miaoli County, Taiwan., Chen HC; Department of Psychiatry, National Taiwan University Hospital, Taipei, Taiwan., Crawford S; Center for Eating Disorders at Sheppard Pratt, Baltimore, Maryland., Crow S; Department of Psychiatry, University of Minnesota, Minneapolis, Minnesota., DiBlasi E; Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, Utah., Duriez P; Hôpital Sainte-Anne, GHU Paris Psychiatrie et Neurosciences, Paris, France; Institute of Psychiatry and Neuroscience of Paris, INSERM U1266, Université de Paris, Paris, France., Fernández-Aranda F; Department of Psychiatry, University Hospital Bellvitge-IDIBELL and CIBEROBN, Barcelona, Spain., Fichter MM; Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University, Munich, Germany; Schön Klinik Roseneck affiliated with the Medical Faculty of the University of Munich, Munich, Germany., Gallinger S; Department of Surgery, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Glatt SJ; Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, Syracuse, New York., Gorwood P; Hôpital Sainte-Anne, GHU Paris Psychiatrie et Neurosciences, Paris, France; Institute of Psychiatry and Neuroscience of Paris, INSERM U1266, Université de Paris, Paris, France., Guo Y; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Hakonarson H; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Halmi KA; Department of Psychiatry, Weill Cornell Medical College, New York, New York., Hwu HG; Department of Psychiatry, National Taiwan University Hospital and College of Medicine, Taipei, Taiwan., Jain S; Biostatistics Research Center, Herbert Wertheim School of Public Health and Human Longevity Science, La Jolla, California., Jamain S; Inserm U955, Institut Mondor de recherches Biomédicales, Laboratoire, Neuro-Psychiatrie Translationnelle, and Fédération Hospitalo-Universitaire de Précision Médecine en Addictologie et Psychiatrie, University Paris-Est-Créteil, Créteil, France., Jiménez-Murcia S; Department of Psychiatry, University Hospital Bellvitge-IDIBELL and CIBEROBN, Barcelona, Spain., Johnson C; Eating Recovery Center, Denver, Colorado., Kaplan AS; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada; Centre for Addiction and Mental Health, Toronto, Ontario, Canada., Kaye WH; Department of Psychiatry, Department of Psychiatry, University of California San Diego, San Diego, California., Keel PK; Department of Psychology, Florida State University, Tallahassee, Florida., Kennedy JL; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada; Centre for Addiction and Mental Health, Toronto, Ontario, Canada., Klump KL; Department of Psychology, Michigan State University, Lansing, Michigan., Li D; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Liao SC; Department of Psychiatry, National Taiwan University Hospital, Taipei, Taiwan., Lieb K; Department of Psychiatry and Psychotherapy, University Medical Center, Mainz, Germany., Lilenfeld L; Department of Clinical Psychology, The Chicago School of Professional Psychology, Washington, DC., Liu CM; Department of Psychiatry, National Taiwan University Hospital, Taipei, Taiwan., Magistretti PJ; BESE Division, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia; Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Marshall CR; Department of Paediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada., Mitchell JE; Department of Psychiatry and Behavioral Science, University of North Dakota School of Medicine and Health Sciences, Fargo, North Dakota., Monson ET; Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, Utah., Myers RM; HudsonAlpha Institute for Biotechnology, Huntsville, Alabama., Pinto D; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York., Powers A; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia., Ramoz N; Institute of Psychiatry and Neuroscience of Paris, INSERM U1266, Université de Paris, Paris, France., Roepke S; Department of Psychiatry, Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Campus Benjamin Franklin, Berlin, Germany., Rozanov V; Department of Psychology, St. Petersburg State University, Saint Petersburg, Russian Federation; Department of Borderline Disorders and Psychotherapy, V.M. Bekhterev National Medical Research Center for Psychiatry and Neurology, Saint Petersburg, Russian Federation., Scherer SW; Department of Genetics and Genomic Biology, The Hospital for Sick Children, Toronto, Ontario, Canada., Schmahl C; Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Sokolowski M; National Centre for Suicide Research and Prevention of Mental Ill-Health, LIME, Karolinska Institutet, Stockholm, Sweden., Strober M; David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California; Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California., Thornton LM; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Treasure J; Institute of Psychiatry, Psychology and Neuroscience, Department of Psychological Medicine, London, United Kingdom; National Institute for Health Research Biomedical Research Centre, King's College London and South London and Maudsley National Health Service Foundation Trust, London, United Kingdom., Tsuang MT; Center for Behavioral Genomics, Department of Psychiatry, University of California San Diego, San Diego, California., Witt SH; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Woodside DB; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada; Centre for Mental Health, University Health Network, Toronto, Ontario, Canada; Program for Eating Disorders, University Health Network, Toronto, Ontario, Canada., Yilmaz Z; National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Zillich L; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Adolfsson R; Department of Clinical Sciences, Psychiatry, Umeå University Medical Faculty, Umeå, Sweden., Agartz I; Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden; Department of Psychiatric Research, Diakonhjemmet Hospital, Oslo, Norway; NORMENT, Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Air TM; Discipline of Psychiatry, University of Adelaide, Adelaide, South Australia, Australia., Alda M; Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada; National Institute of Mental Health, Klecany, Czech Republic., Alfredsson L; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; Institut of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Andreassen OA; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway; NORMENT, University of Oslo, Oslo, Norway., Anjorin A; Psychiatry, Berkshire Healthcare NHS Foundation Trust, Bracknell, United Kingdom., Appadurai V; Institute of Biological Psychiatry, Copenhagen Mental Health Services, Copenhagen University Hospital, Copenhagen, Denmark; Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Copenhagen, Denmark., Soler Artigas M; Department of Psychiatry, Hospital Universitari Vall d'Hebrón, Barcelona, Spain; Department of Genetics, Microbiology & Statistics, University of Barcelona, Barcelona, Spain; Psychiatric Genetics Unit, Group of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona, Barcelona, Spain; Biomedical Network Research Centre on Mental Health, Instituto de Salud Carlos III, Madrid, Spain., Van der Auwera S; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Mecklenburg-Vorpommern, Germany., Azevedo MH; Department of Psychiatry, University of Coimbra, Coimbra, Portugal., Bass N; Division of Psychiatry, University College London, London, United Kingdom., Bau CHD; Laboratory of Developmental Psychiatry, Adult Division, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil; Department of Genetics, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil., Baune BT; Department of Psychiatry, Melbourne Medical School, University of Melbourne, Melbourne, Victoria, Australia; Department of Psychiatry, University of Münster, Münster, Nordrhein-Westfalen, Germany., Bellivier F; Department of Psychiatry and Addiction Medicine, Assistance Publique Hôpitaux de Paris, Paris, France; Paris Bipolar and TRD Expert Centres, FondaMental Foundation, Paris, France; UMR-S1144 Team 1: Biomarkers of relapse and therapeutic response in addiction and mood disorders, INSERM, Paris, France; Psychiatry, Université Paris Diderot, Paris, France., Berger K; Institute of Epidemiology and Social Medicine, University of Münster, Münster, Nordrhein-Westfalen, Germany., Biernacka JM; Health Sciences Research, Mayo Clinic, Rochester, Minnesota., Bigdeli TB; Department of Psychiatry and Behavioral Sciences, State University of New York Downstate Medical Center, New York, New York; Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia., Binder EB; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany., Boehnke M; Center for Statistical Genetics and Department of Biostatistics, Institute for Social Research, University of Michigan, Ann Arbor, Michigan., Boks MP; Department of Psychiatry, UMC Utrecht Hersencentrum, Utrecht, the Netherlands., Bosch R; Department of Psychiatry, Hospital Universitari Vall d'Hebrón, Barcelona, Spain; Department of Psychiatry and Legal Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain; Biomedical Network Research Centre on Mental Health, Instituto de Salud Carlos III, Madrid, Spain., Braff DL; Department of Psychiatry, University of California San Diego, La Jolla, California., Bryant R; School of Psychology, University of New South Wales, Sydney, New South Wales, Australia., Budde M; Institute of Psychiatric Phenomics and Genomics, University Hospital, Ludwig-Maximilians-University, Munich, Germany., Byrne EM; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia; Centre for Children's Health Research, The University of Queensland, Brisbane, Queensland, Australia., Cahn W; Department of Psychiatry, UMC Utrecht Hersencentrum, Utrecht, the Netherlands., Casas M; Department of Psychiatry, Hospital Universitari Vall d'Hebrón, Barcelona, Spain; Psychiatric Genetics Unit, Group of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona, Barcelona, Spain; Department of Psychiatry and Legal Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain; Biomedical Network Research Centre on Mental Health, Instituto de Salud Carlos III, Madrid, Spain., Castelao E; Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Cervilla JA; Mental Health Unit, Department of Psychiatry, Faculty of Medicine, Granada University Hospital Complex, Biomedical Research Centre, University of Granada, Granada, Spain., Chaumette B; Institut de Psychiatrie, CNRS GDR 3557, Paris, France; Department of Evaluation, Prevention and Therapeutic innovation, GHU Paris Psychiatrie et Neurosciences, Paris, France; Team Pathophysiology of psychiatric diseases, Université de Paris, Institute of Psychiatry and Neuroscience of Paris, INSERM U1266, Paris, France., Cichon S; Institute of Neuroscience and Medicine, Research Centre Jülich, Jülich, Germany; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland; Department of Biomedicine, University Hospital Basel, Basel, Switzerland; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany., Corvin A; Neuropsychiatric Genetics Research Group, Department of Psychiatry and Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland., Craddock N; Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, United Kingdom., Craig D; Department of Translational Genomics, University of Southern California, Pasadena, California., Degenhardt F; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany., Djurovic S; Department of Medical Genetics, Oslo University Hospital, Oslo, Norway; NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway., Edenberg HJ; Department of Medical & Molecular Genetics, Indiana University, Indianapolis, Indiana; Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana., Fanous AH; Department of Psychiatry and Behavioral Sciences, State University of New York Downstate Medical Center, New York, New York; Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia., Foo JC; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Forstner AJ; Institute of Neuroscience and Medicine, Research Centre Jülich, Jülich, Germany; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany; Centre for Human Genetics, University of Marburg, Marburg, Germany., Frye M; Department of Psychiatry & Psychology, Mayo Clinic, Rochester, Minnesota., Fullerton JM; School of Medical Sciences, University of New South Wales, Sydney, New South Wales, Australia; Neuroscience Research Australia, Sydney, New South Wales, Australia., Gatt JM; School of Psychology, University of New South Wales, Sydney, New South Wales, Australia; Neuroscience Research Australia, Sydney, New South Wales, Australia., Gejman PV; Department of Psychiatry and Behavioral Sciences, NorthShore University HealthSystem, Evanston, Illinois; Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, Illinois., Giegling I; Department of Psychiatry, University of Munich, Munich, Germany; Department of Psychiatry, Psychotherapy and Psychosomatics, Martin-Luther-University Halle-Wittenberg, Halle, Germany., Grabe HJ; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Mecklenburg-Vorpommern, Germany., Green MJ; School of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia; Neuroscience Research Australia, Sydney, New South Wales, Australia., Grevet EH; ADHD Outpatient Program, Adult Division, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil; Department of Psychiatry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil., Grigoroiu-Serbanescu M; Biometric Psychiatric Genetics Research Unit, Alexandru Obregia Clinical Psychiatric Hospital, Bucharest, Romania., Gutierrez B; Department of Psychiatry, Biomedical Research Centre, University of Granada, Granada, Spain., Guzman-Parra J; Mental Health Department, University Regional Hospital, Biomedicine Institute, Málaga, Spain., Hamilton SP; Psychiatry, Kaiser Permanente Northern California, San Francisco, California., Hamshere ML; Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, United Kingdom., Hartmann A; Department of Psychiatry, Psychotherapy and Psychosomatics, Martin-Luther-University Halle-Wittenberg, Halle, Germany., Hauser J; Department of Psychiatry, Laboratory of Psychiatric Genetics, Poznan University of Medical Sciences, Poznań, Poland., Heilmann-Heimbach S; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany., Hoffmann P; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland; Department of Biomedicine, University Hospital Basel, Basel, Switzerland; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany., Ising M; Max Planck Institute of Psychiatry, Munich, Germany., Jones I; Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, United Kingdom., Jones LA; Department of Psychological Medicine, University of Worcester, Worcester, United Kingdom., Jonsson L; Department of Psychiatry and Neuroscience, University of Gothenburg, Gothenburg, Sweden., Kahn RS; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York; Department of Psychiatry, UMC Utrecht Hersencentrum, Utrecht, the Netherlands., Kelsoe JR; Department of Psychiatry, University of California San Diego, La Jolla, California; Institute for Genomic Medicine, University of California San Diego, La Jolla, California., Kendler KS; Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia., Kloiber S; Max Planck Institute of Psychiatry, Munich, Germany; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Centre for Addiction and Mental Health, Toronto, Ontario, Canada., Koenen KC; Stanley Center for Psychiatric Research, Broad Institute, Cambridge, Massachusetts; Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts; Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, Massachusetts., Kogevinas M; Center for Research in Environmental Epidemiology, Barcelona, Spain., Konte B; Department of Psychiatry, Psychotherapy and Psychosomatics, Martin-Luther-University Halle-Wittenberg, Halle, Germany., Krebs MO; Institut de Psychiatrie, CNRS GDR 3557, Paris, France; Department of Evaluation, Prevention and Therapeutic innovation, GHU Paris Psychiatrie et Neurosciences, Paris, France; Team Pathophysiology of psychiatric diseases, Université de Paris, Institute of Psychiatry and Neuroscience of Paris, INSERM U1266, Paris, France., Landén M; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Department of Psychiatry and Neuroscience, University of Gothenburg, Gothenburg, Sweden., Lawrence J; Psychiatry, North East London NHS Foundation Trust, Ilford, Cheshire, United Kingdom., Leboyer M; Faculté de Médecine, University Paris-Est-Créteil, Créteil, France; Department of Psychiatry and Addiction Medicine, Assistance Publique Hôpitaux de Paris, Paris, France; INSERM, Paris, France., Lee PH; Stanley Center for Psychiatric Research, Broad Institute, Cambridge, Massachusetts; Analytical and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts; Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts., Levinson DF; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California., Liao C; Department of Human Genetics, Faculty of Medicine, McGill University, Montreal, Québec, Canada; Montreal Neurological Institute and Hospital, Montreal, Québec, Canada., Lissowska J; Cancer Epidemiology and Prevention, Sklodowska-Curie Cancer Center and Institute of Oncology, Warsaw, Poland., Lucae S; Max Planck Institute of Psychiatry, Munich, Germany., Mayoral F; Mental Health Department, University Regional Hospital, Biomedicine Institute, Málaga, Spain., McElroy SL; Research Institute, Lindner Center of HOPE, Mason, Ohio., McGrath P; Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, New York., McGuffin P; Social Genetic and Developmental Psychiatry Centre, King's College London, London, United Kingdom., McQuillin A; Division of Psychiatry, University College London, London, United Kingdom., Medland SE; Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Mehta D; Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia; School of Psychology and Counseling, Queensland University of Technology, Brisbane, Queensland, Australia., Melle I; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway; Division of Mental Health and Addiction, University of Oslo, Institute of Clinical Medicine, Oslo, Norway., Milaneschi Y; Department of Psychiatry, Amsterdam UMC, Vrije Universiteit and GGZ inGeest, Amsterdam, Netherlands., Mitchell PB; School of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia., Molina E; Department of Nursing, Faculty of Medicine, Biomedical Research Centre, University of Granada, Granada, Spain., Morken G; Mental Health, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, NTNU, Trondheim, Norway; Psychiatry, St. Olavs University Hospital, Trondheim, Norway., Mortensen PB; Centre for Integrative Sequencing, Aarhus University, Aarhus, Denmark; National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark; Centre for Integrated Register-based Research, Aarhus University, Aarhus, Denmark; Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Copenhagen, Denmark., Müller-Myhsok B; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany; Munich Cluster for Systems Neurology, Munich, Germany; University of Liverpool, Liverpool, United Kingdom., Nievergelt C; Department of Psychiatry, University of California San Diego, La Jolla, California., Nimgaonkar V; Psychiatry and Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania., Nöthen MM; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany., O'Donovan MC; Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, United Kingdom., Ophoff RA; Jane and Terry Semel Institute for Neuroscience and Human Behavior, Los Angeles, California; Psychiatry, Erasmus University Medical Center, Rotterdam, the Netherlands., Owen MJ; Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, United Kingdom., Pato C; College of Medicine Institute for Genomic Health, SUNY Downstate Medical Center College of Medicine, Brooklyn, New York; Institute for Genomic Health, SUNY Downstate Medical Center College of Medicine, Brooklyn, New York., Pato MT; Institute for Genomic Health, SUNY Downstate Medical Center College of Medicine, Brooklyn, New York., Penninx BWJH; Department of Psychiatry, Amsterdam UMC, Vrije Universiteit and GGZ inGeest, Amsterdam, Netherlands., Pimm J; Division of Psychiatry, University College London, London, United Kingdom., Pistis G; Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Potash JB; Department of Psychiatry, University of Iowa, Iowa City, Iowa., Power RA; Social Genetic and Developmental Psychiatry Centre, King's College London, London, United Kingdom; Genetics, BioMarin Pharmaceuticals, London, United Kingdom; University of Oxford, St. Edmund Hall, Oxford, United Kingdom., Preisig M; Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Quested D; Department of Psychiatry, University of Oxford, Oxford, United Kingdom., Ramos-Quiroga JA; Department of Psychiatry, Hospital Universitari Vall d'Hebrón, Barcelona, Spain; Psychiatric Genetics Unit, Group of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona, Barcelona, Spain; Department of Psychiatry and Legal Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain; Biomedical Network Research Centre on Mental Health, Instituto de Salud Carlos III, Madrid, Spain., Reif A; Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt, Germany., Ribasés M; Department of Psychiatry, Hospital Universitari Vall d'Hebrón, Barcelona, Spain; Department of Genetics, Microbiology & Statistics, University of Barcelona, Barcelona, Spain; Psychiatric Genetics Unit, Group of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona, Barcelona, Spain; Biomedical Network Research Centre on Mental Health, Instituto de Salud Carlos III, Madrid, Spain., Richarte V; Department of Psychiatry, Hospital Universitari Vall d'Hebrón, Barcelona, Spain; Department of Psychiatry and Legal Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain; Biomedical Network Research Centre on Mental Health, Instituto de Salud Carlos III, Madrid, Spain., Rietschel M; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Rivera M; Social Genetic and Developmental Psychiatry Centre, King's College London, London, United Kingdom; Department of Biochemistry and Molecular Biology II and Institute of Neurosciences, Biomedical Research Centre, University of Granada, Granada, Spain., Roberts A; Department of Environmental Health, Harvard TH Chan School of Public Health, Boston, Massachusetts., Roberts G; School of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia., Rouleau GA; Department of Neurology and Neurosurgery, Faculty of Medicine, McGill University, Montreal, Québec, Canada; Montreal Neurological Institute and Hospital, Montreal, Québec, Canada., Rovaris DL; Department of Physiology and Biophysics, Instituto de Ciencias Biomedicas Universidade de Sao Paulo, São Paulo, Brazil., Rujescu D; Department of Psychiatry, Psychotherapy and Psychosomatics, Martin-Luther-University Halle-Wittenberg, Halle, Germany., Sánchez-Mora C; Department of Psychiatry, Hospital Universitari Vall d'Hebrón, Barcelona, Spain; Department of Genetics, Microbiology & Statistics, University of Barcelona, Barcelona, Spain; Psychiatric Genetics Unit, Group of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona, Barcelona, Spain; Biomedical Network Research Centre on Mental Health, Instituto de Salud Carlos III, Madrid, Spain., Sanders AR; Department of Psychiatry and Behavioral Sciences, NorthShore University HealthSystem, Evanston, Illinois; Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, Illinois., Schofield PR; School of Medical Sciences, University of New South Wales, Sydney, New South Wales, Australia; Neuroscience Research Australia, Sydney, New South Wales, Australia., Schulze TG; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland; Institute of Psychiatric Phenomics and Genomics, University Hospital, Ludwig-Maximilians-University, Munich, Germany; Human Genetics Branch, Intramural Research Program, National Institute of Mental Health, Bethesda, Maryland; Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany., Scott LJ; Center for Statistical Genetics and Department of Biostatistics, Institute for Social Research, University of Michigan, Ann Arbor, Michigan., Serretti A; Department of Biomedical and NeuroMotor Sciences, University of Bologna, Bologna, Italy., Shi J; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland., Shyn SI; Behavioral Health Services, Kaiser Permanente Washington, Seattle, Washington, DC., Sirignano L; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Sklar P; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York., Smeland OB; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway; NORMENT, University of Oslo, Oslo, Norway., Smoller JW; Stanley Center for Psychiatric Research, Broad Institute, Cambridge, Massachusetts; Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts; Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts., Sonuga-Barke EJS; Institute of Psychology, Psychiatry & Neuroscience, King's College London, London, United Kingdom., Spalletta G; Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, Texas; Laboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation, Rome, Italy., Strauss JS; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Centre for Addiction and Mental Health, Toronto, Ontario, Canada., Świątkowska B; Department of Environmental Epidemiology, Nofer Institute of Occupational Medicine, Lódz, Poland., Trzaskowski M; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia., Turecki G; Department of Psychiatry, Faculty of Medicine, McGill University, Montreal, Québec, Canada., Vilar-Ribó L; Department of Psychiatry, Hospital Universitari Vall d'Hebrón, Barcelona, Spain; Psychiatric Genetics Unit, Group of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona, Barcelona, Spain., Vincent JB; Molecular Brain Science, Centre for Addiction and Mental Health, Toronto, Ontario, Canada., Völzke H; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Mecklenburg-Vorpommern, Germany., Walters JTR; Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, United Kingdom., Shannon Weickert C; School of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia; Neuroscience Research Australia, Sydney, New South Wales, Australia., Weickert TW; School of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia; Neuroscience Research Australia, Sydney, New South Wales, Australia., Weissman MM; Columbia University College of Physicians and Surgeons, New York, New York; Division of Translational Epidemiology, New York State Psychiatric Institute, New York, New York., Williams LM; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California., Wray NR; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia; Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia., Zai CC; Stanley Center for Psychiatric Research, Broad Institute, Cambridge, Massachusetts; Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, Massachusetts; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada; Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada; Molecular Brain Science, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada., Ashley-Koch AE; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, North Carolina., Beckham JC; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina; VISN 6 Mid-Atlantic Mental Illness Research, Durham Veterans Affairs Health Care System, Durham, North Carolina., Hauser ER; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, North Carolina; Cooperative Studies Program Epidemiology Center, Education, and Clinical Center, Durham Veterans Affairs Health Care System, Durham, North Carolina., Hauser MA; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, North Carolina., Kimbrel NA; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina; VISN 6 Mid-Atlantic Mental Illness Research, Durham Veterans Affairs Health Care System, Durham, North Carolina., Lindquist JH; VA Health Services Research and Development Center of Innovation to Accelerate Discovery and Practice Transformation, Durham Veterans Affairs Health Care System, Durham, North Carolina., McMahon B; Theoretical Division, Los Alamos National Laboratory, Los Alamos National Laboratory, Los Alamos, New Mexico., Oslin DW; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; VISN 4 Mental Illness Research, Education, and Clinical Center, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, Pennsylvania., Qin X; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, North Carolina., Agerbo E; National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark; Centre for Integrated Register-based Research, Aarhus University, Aarhus, Denmark; Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark., Børglum AD; Centre for Genomics and Personalized Medicine, Aarhus University, Aarhus, Denmark; Centre for Integrative Sequencing, Aarhus University, Aarhus, Denmark; Department of Biomedicine, Aarhus University, Aarhus, Denmark; Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus University, Aarhus, Denmark., Breen G; National Institute for Health Research Maudsley Biomedical Research Centre at South London and Maudsley NHS Foundation Trust, London, United Kingdom; Social Genetic and Developmental Psychiatry Centre, King's College London, London, United Kingdom., Erlangsen A; Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus University, Aarhus, Denmark; Department of Mental Health, Johns Hopkins University School of Medicine, Baltimore, Maryland; Danish Research Institute for Suicide Prevention, Mental Health Centre Copenhagen, Copenhagen, Denmark; Center of Mental Health Research, Australian National University, Canberra, Australia., Esko T; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Gelernter J; Department of Psychiatry, Veterans Affairs Connecticut Healthcare Center, West Haven, Connecticut; Division of Human Genetics, Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut., Hougaard DM; Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark; Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark., Kessler RC; Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts., Kranzler HR; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; VISN 4 Mental Illness Research, Education, and Clinical Center, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, Pennsylvania., Li QS; Neuroscience, Janssen Research & Development, LLC, Titusville, New Jersey., Martin NG; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia., McIntosh AM; Division of Psychiatry, University of Edinburgh, Edinburgh, United Kingdom., Mors O; Psychosis Research Unit, Aarhus University, Aarhus, Denmark; Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark., Nordentoft M; Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark; Mental Health Center Copenhagen, Copenhagen University Hospital, Copenhagen, Denmark., Olsen CM; Department of Population Health, QIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia., Porteous D; Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom., Ursano RJ; Department of Psychiatry, Uniformed University of the Health Sciences, Bethesda, Maryland., Wasserman D; National Centre for Suicide Research and Prevention of Mental Ill-Health, LIME, Karolinska Institutet, Stockholm, Sweden., Werge T; Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark; Institute of Biological Psychiatry, Copenhagen Mental Health Services, Copenhagen University Hospital, Copenhagen, Denmark; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark; Lundbeck Foundation GeoGenetics Centre, GLOBE Institute, University of Copenhagen, Copenhagen, Denmark., Whiteman DC; Department of Population Health, QIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia., Bulik CM; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Coon H; Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, Utah; Biomedical Informatics, University of Utah School of Medicine, Salt Lake City, Utah., Demontis D; Centre for Genomics and Personalized Medicine, Aarhus University, Aarhus, Denmark; Centre for Integrative Sequencing, Aarhus University, Aarhus, Denmark; Department of Biomedicine, Aarhus University, Aarhus, Denmark; Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus University, Aarhus, Denmark., Docherty AR; Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia; Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, Utah., Kuo PH; Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan; Department of Psychiatry, National Taiwan University Hospital, Taipei, Taiwan., Lewis CM; Department of Medical & Molecular Genetics, King's College London, London, United Kingdom; Social Genetic and Developmental Psychiatry Centre, King's College London, London, United Kingdom., Mann JJ; Departments of Psychiatry and Radiology, Columbia University, New York, New York., Rentería ME; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia; School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia., Smith DJ; Institute of Health and Wellbeing, University of Glasgow, Glasgow, United Kingdom., Stahl EA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts., Stein MB; Department of Psychiatry and School of Public Health, University of California San Diego, La Jolla, California., Streit F; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Willour V; Department of Psychiatry, University of Iowa, Iowa City, Iowa., Ruderfer DM; Division of Genetic Medicine, Department of Medicine, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, Tennessee. Electronic address: douglas.ruderfer@vanderbilt.edu.

Publikováno v: Biological psychiatry [Biol Psychiatry] 2022 Feb 01; Vol. 91 (3), pp. 313-327. Date of Electronic Publication: 2021 Sep 09.

Quantum computing at the frontiers of biological sciences.

Autor: Emani PS; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA., Warrell J; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA., Anticevic A; Yale School of Medicine, Department of Psychiatry, New Haven, CT, USA., Bekiranov S; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA, USA., Gandal M; Department of Psychiatry, Semel Institute, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, CA, USA., McConnell MJ; Lieber Institute for Brain Development, Baltimore, MD, USA., Sapiro G; Department of Electrical and Computer Engineering, Duke University, Durham, NC, USA., Aspuru-Guzik A; Department of Chemistry, University of Toronto, Toronto, Ontario, Canada.; Canadian Institute for Advanced Research (CIFAR) Artificial Intelligence Research Chair, Toronto, Ontario, Canada.; Vector Institute, Toronto, Ontario, Canada.; Department of Computer Science, University of Toronto, Toronto, Ontario, Canada., Baker JT; Institute for Technology in Psychiatry, McLean Hospital, Belmont, MA, USA.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA., Bastiani M; Sir Peter Mansfield Imaging Centre, School of Medicine, University of Nottingham, Nottingham, UK.; Wellcome Centre for Integrative Neuroimaging, FMRIB Centre, Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford, UK., Murray JD; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; Department of Physics, Yale University, New Haven, CT, USA., Sotiropoulos SN; Sir Peter Mansfield Imaging Centre, School of Medicine, University of Nottingham, Nottingham, UK.; NIHR Nottingham Biomedical Research Centre, Queen's Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK., Taylor J; Joint Center for Quantum Information and Computer Science, University of Maryland, College Park, MD, USA.; National Institute of Standards and Technology, Gaithersburg, MD, USA., Senthil G; New York Genome Center, New York, NY, USA., Lehner T; New York Genome Center, New York, NY, USA. tlehner@gmail.com.; National Institute of Mental Health, Bethesda, MD, USA. tlehner@gmail.com.; Neuropsychiatric Disease Genomics, New York Genome Center, New York, NY, USA. tlehner@gmail.com., Gerstein MB; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA. mark@gersteinlab.org.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA. mark@gersteinlab.org.; Department of Computer Science, Yale University, New Haven, CT, USA. mark@gersteinlab.org.; Department of Statistics and Data Science, Yale University, New Haven, CT, USA. mark@gersteinlab.org., Harrow AW; Center for Theoretical Physics, Department of Physics, Massachusetts Institute of Technology, Cambridge, MA, USA. aram@mit.edu.

Publikováno v: Nature methods [Nat Methods] 2021 Jul; Vol. 18 (7), pp. 701-709.

Network integration and segregation changes in schizophrenia: impact of electroconvulsive therapy.

Autor: Ding, Ningning^1,2 (AUTHOR), Zhang, Entu^1,2 (AUTHOR), Liu, Yangyang^2,3 (AUTHOR), Zhang, Shuaiqi^1,2 (AUTHOR), Lu, Pei^2,3 (AUTHOR), Zhang, Haisan^1,2 (AUTHOR) zhs386@163.com

Publikováno v: BMC Psychiatry. 11/30/2024, Vol. 24 Issue 1, p1-11. 11p.