Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Gan-Hong Chen"'
Autor:
Zhi-Min Deng, Gan-Hong Chen, Fang-Fang Dai, Shi-Yi Liu, Dong-Yong Yang, An-Yu Bao, Yan-Xiang Cheng
Publikováno v:
PLoS ONE, Vol 17, Iss 4, p e0267108 (2022)
Previous work has demonstrated that the expression of microRNA-21 (miR-21) is implicated in cervical cancer (CC). However, little is known regarding its associations with clinical parameters. We first conducted a meta-analysis using data from Gene Ex
Externí odkaz:
https://doaj.org/article/5f4c206313c2419987d0ae2f4f07c495
Autor:
Gan-Hong Chen, 陳建宏
93
A novel plant defensin gene named VrCRP (Vigna radiata Cysteine Rich Protein) was previously isolated from a bruchid resistant nearly isogenic line of mungbean Vigna radiate VC6089A by suppression subtractive hybridization, and was expressed
A novel plant defensin gene named VrCRP (Vigna radiata Cysteine Rich Protein) was previously isolated from a bruchid resistant nearly isogenic line of mungbean Vigna radiate VC6089A by suppression subtractive hybridization, and was expressed
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/74162768936699701697
Publikováno v:
Biomedical Journal of Scientific & Technical Research. 13
Rotational barriers of ten 4-acyloxy-4'-N-n-butylcarbamyloxy-biphenyls were calculated by density functional theory. Linear free energy relationships between rotational barriers and reduced mass existed in these compounds...
Publikováno v:
Journal of the Chinese Chemical Society. 63:709-715
Obesity is a complex health issue and it can cause many health and social problems. Previous studies reported that lipase is a main target for obesity treatment. We synthesized R-exo-2-norbornyl-N-n-butylcarbamate and S-exo-2-norbornyl-N-n-butylcarba
Publikováno v:
Canadian Journal of Chemistry. 94:72-77
The kinetic studies and drug designs of butyrylcholinesterase play an important role in the development of Alzheimer’s disease therapeutics. In this research, automated docking studies were performed to provide useful insights into butyrylcholinest
Autor:
Gan-Hong Chen, Ning-Shian Hsu, Der-Ren Hwang, Shan-He Chen, Chi-Huey Wong, Ying-Ta Wu, Tsung-Lin Li
Publikováno v:
ACS Chemical Biology. 7:481-486
In our effort to improve the efficiency and yield of xylose-to-ethanol bioconversion in Pichia stipitis, the transaldolase (TAL) in the pentose phosphate pathway was identified as a rate-limiting enzyme for improvement. A mutant containing the Q263R
Publikováno v:
QSAR & Combinatorial Science. 24:943-952
4-Acyloxy-biphenyl-4'-N-butylcarbamates (1-8) are synthesized from 4,4'-biphenol by two-step reactions. Carbamates 1-7 are characterized as the pseudo-substrate inhibitors of butyrylcholinesterase. In other words, carbamates 1-7 bind to the enzyme an
Publikováno v:
European Journal of Lipid Science and Technology. 107:65-73
4,4'-Biphenyl-4-acylate-4'-N-n-butylcarbamates (1-8) are synthesized and characterized as highly potent and selective pseudo-substrate inhibitors of Pseudomonas species lipase. Thus, the n-butylcarbamate moieties of the inhibitors bind to the first a
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 19:234-243
Biphenyl-4-acyoxylate-4′-N-butylcarbamates 1–8 are synthesized from 4,4′-biphenol and are characterized as the pseudosubstrate inhibitors of acetylcholinesterase. In other words, the inhibitors bind to the enzyme and react with the enzyme to fo
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 8:2747-2750
Conformationally restricted carbamate inhibitors, exo -2-norbornyl- N -butylcarbamate ( 1 ), endo -2-norbornyl- N -butylcarbamate ( 2 ), 1-adamantyl- N -butylcarbamate ( 3 ), and 2-adamantyl- N -butylcarbamate ( 4 ) as active site-directed irreversib