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Ershen Zhenwu Decoction suppresses myocardial fibrosis of chronic heart failure with heart-kidney Yang deficiency by down-regulating the Ras Homolog Gene Family Member A/Rho-Associated Coiled-Coil Kinases signaling pathway.

Autor: Cheng D; First Affiliated Hospital of Anhui University of Chinese Medicine, Anhui University of Chinese Medicine, Hefei, China; Shuguang Hospital Affiliated with Shanghai University of Chinese Medicine, Anhui Hospital, Hefei, China; Xin'an Key Laboratory of Medical Science, Ministry of Education, Anhui University of Chinese Medicine, Hefei, China., Sheng S; Shuguang Hospital Affiliated with Shanghai University of Chinese Medicine, Anhui Hospital, Hefei, China; Xin'an Key Laboratory of Medical Science, Ministry of Education, Anhui University of Chinese Medicine, Hefei, China., Hu J; First Affiliated Hospital of Anhui University of Chinese Medicine, Anhui University of Chinese Medicine, Hefei, China; Xin'an Key Laboratory of Medical Science, Ministry of Education, Anhui University of Chinese Medicine, Hefei, China., Cai S; First Affiliated Hospital of Anhui University of Chinese Medicine, Anhui University of Chinese Medicine, Hefei, China; Xin'an Key Laboratory of Medical Science, Ministry of Education, Anhui University of Chinese Medicine, Hefei, China., Liu Y; First Affiliated Hospital of Anhui University of Chinese Medicine, Anhui University of Chinese Medicine, Hefei, China; Xin'an Key Laboratory of Medical Science, Ministry of Education, Anhui University of Chinese Medicine, Hefei, China., Gan R; School of Pharmacy, Anhui University of Chinese Medicine, Hefei, China., Zhu Z; First Affiliated Hospital of Anhui University of Chinese Medicine, Anhui University of Chinese Medicine, Hefei, China; Xin'an Key Laboratory of Medical Science, Ministry of Education, Anhui University of Chinese Medicine, Hefei, China., Ge L; First Affiliated Hospital of Anhui University of Chinese Medicine, Anhui University of Chinese Medicine, Hefei, China; Xin'an Key Laboratory of Medical Science, Ministry of Education, Anhui University of Chinese Medicine, Hefei, China. Electronic address: gelan311@126.com., Chen W; School of Pharmacy, Anhui University of Chinese Medicine, Hefei, China. Electronic address: wdchen@ahtcm.edu.cn., Cheng X; First Affiliated Hospital of Anhui University of Chinese Medicine, Anhui University of Chinese Medicine, Hefei, China; Xin'an Key Laboratory of Medical Science, Ministry of Education, Anhui University of Chinese Medicine, Hefei, China. Electronic address: cxy478@163.com.

Publikováno v: Journal of ethnopharmacology [J Ethnopharmacol] 2024 Nov 22; Vol. 340, pp. 119146. Date of Electronic Publication: 2024 Nov 22.