Performance analysis of capacity discovery algorithm on hardware platform.

Autor: Gampa, K., Ranade, S.J., Jain, P., Balakrishnan, M., Yemewar, S.

Publikováno v: North American Power Symposium (NAPS), 2010; 2010, p1-7, 7p

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Design and Discovery of N-(2-Methyl-5'-morpholino-6'-((tetrahydro-2H-pyran-4-yl)oxy)-[3,3'-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide (RAF709): A Potent, Selective, and Efficacious RAF Inhibitor Targeting RAS Mutant Cancers.

Autor: Nishiguchi GA; Global Discovery Chemistry, Novartis Institutes for BioMedical Research , 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Rico A; Global Discovery Chemistry, Novartis Institutes for BioMedical Research , 5300 Chiron Way, Emeryville, California 94608, United States., Tanner H; Global Discovery Chemistry, Novartis Institutes for BioMedical Research , 5300 Chiron Way, Emeryville, California 94608, United States., Aversa RJ; Global Discovery Chemistry, Novartis Institutes for BioMedical Research , 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Taft BR; Global Discovery Chemistry, Novartis Institutes for BioMedical Research , 5300 Chiron Way, Emeryville, California 94608, United States., Subramanian S; Global Discovery Chemistry, Novartis Institutes for BioMedical Research , 5300 Chiron Way, Emeryville, California 94608, United States., Setti L; Global Discovery Chemistry, Novartis Institutes for BioMedical Research , 5300 Chiron Way, Emeryville, California 94608, United States., Burger MT; Global Discovery Chemistry, Novartis Institutes for BioMedical Research , 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Wan L; Global Discovery Chemistry, Novartis Institutes for BioMedical Research , 5300 Chiron Way, Emeryville, California 94608, United States., Tamez V; Global Discovery Chemistry, Novartis Institutes for BioMedical Research , 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Smith A; Global Discovery Chemistry, Novartis Institutes for BioMedical Research , 5300 Chiron Way, Emeryville, California 94608, United States., Lou Y; Global Discovery Chemistry, Novartis Institutes for BioMedical Research , 5300 Chiron Way, Emeryville, California 94608, United States., Barsanti PA; Global Discovery Chemistry, Novartis Institutes for BioMedical Research , 5300 Chiron Way, Emeryville, California 94608, United States., Appleton BA; Global Discovery Chemistry, Novartis Institutes for BioMedical Research , 5300 Chiron Way, Emeryville, California 94608, United States., Mamo M; Global Discovery Chemistry, Novartis Institutes for BioMedical Research , 5300 Chiron Way, Emeryville, California 94608, United States., Tandeske L; Oncology, Novartis Institutes for BioMedical Research , 5300 Chiron Way, Emeryville, California 94608, United States., Dix I; Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Novartis Pharma AG , Werk Klybeck, Postfach, CH-4002 Basel, Switzerland., Tellew JE; Genomics Institute of the Novartis Research Foundation , 10675 John Hopkins Drive, San Diego, California 92121, United States., Huang S; Genomics Institute of the Novartis Research Foundation , 10675 John Hopkins Drive, San Diego, California 92121, United States., Mathews Griner LA; Oncology, Novartis Institutes for BioMedical Research , 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Cooke VG; Oncology, Novartis Institutes for BioMedical Research , 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Van Abbema A; Oncology, Novartis Institutes for BioMedical Research , 5300 Chiron Way, Emeryville, California 94608, United States., Merritt H; Oncology, Novartis Institutes for BioMedical Research , 5300 Chiron Way, Emeryville, California 94608, United States., Ma S; Oncology, Novartis Institutes for BioMedical Research , 5300 Chiron Way, Emeryville, California 94608, United States., Gampa K; Oncology, Novartis Institutes for BioMedical Research , 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Feng F; Oncology, Novartis Institutes for BioMedical Research , 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Yuan J; Oncology, Novartis Institutes for BioMedical Research , 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Wang Y; Oncology, Novartis Institutes for BioMedical Research , 5300 Chiron Way, Emeryville, California 94608, United States., Haling JR; Genomics Institute of the Novartis Research Foundation , 10675 John Hopkins Drive, San Diego, California 92121, United States., Vaziri S; Genomics Institute of the Novartis Research Foundation , 10675 John Hopkins Drive, San Diego, California 92121, United States., Hekmat-Nejad M; Oncology, Novartis Institutes for BioMedical Research , 5300 Chiron Way, Emeryville, California 94608, United States., Jansen JM; Global Discovery Chemistry, Novartis Institutes for BioMedical Research , 5300 Chiron Way, Emeryville, California 94608, United States., Polyakov V; Global Discovery Chemistry, Novartis Institutes for BioMedical Research , 5300 Chiron Way, Emeryville, California 94608, United States., Zang R; Global Discovery Chemistry, Novartis Institutes for BioMedical Research , 5300 Chiron Way, Emeryville, California 94608, United States., Sethuraman V; Oncology, Novartis Institutes for BioMedical Research , 5300 Chiron Way, Emeryville, California 94608, United States., Amiri P; Oncology, Novartis Institutes for BioMedical Research , 5300 Chiron Way, Emeryville, California 94608, United States., Singh M; Oncology, Novartis Institutes for BioMedical Research , 5300 Chiron Way, Emeryville, California 94608, United States., Lees E; Oncology, Novartis Institutes for BioMedical Research , 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Shao W; Oncology, Novartis Institutes for BioMedical Research , 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Stuart DD; Oncology, Novartis Institutes for BioMedical Research , 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Dillon MP; Global Discovery Chemistry, Novartis Institutes for BioMedical Research , 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States., Ramurthy S; Global Discovery Chemistry, Novartis Institutes for BioMedical Research , 5300 Chiron Way, Emeryville, California 94608, United States.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2017 Jun 22; Vol. 60 (12), pp. 4869-4881. Date of Electronic Publication: 2017 Jun 08.