Výsledky vyhledávání - "Gamini Weeratunga"

Continuous Flow Process for Reductive Deoxygenation of ω-Chloroketone in the Synthesis of Vilazodone

Autor: Boris Gorin, Gamini Weeratunga, Patel Dineshkumar N, Avedis Karadeolian, Prabhudas Bodhuri

Publikováno v: Organic Process Research & Development. 22:1022-1028

A continuous flow process for the reductive deoxygenation of 3-(4-chlorobutanoyl)-1H-indole-5-carbonitrile to 3-(4-chlorobutyl)-1H-indole-5-carbonitrile was developed using a continuous stirred tank reactor (CSTR) setup. The opportunity for process o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cd3c3112ab6a5f5e0e48eeb9adb8d48d
https://doi.org/10.1021/acs.oprd.8b00145

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ChemInform Abstract: Regioselective Diels-Alder Reactions of N-Cyanoindole-4,7-diones: Elaboration of the A-Ring of the Kinamycins on a BC Ring Template

Autor: Gary I. Dmitrienko, John Dilley, Nicholas J. Taylor, Gamini Weeratunga, Ganesh K.B. Prasad

Publikováno v: ChemInform. 22

The indole-4,7-dione 3a undergoes regioselective Diels-Alder reactions in accord with the prediction of Frontier Molecular Orbital analysis to yield a precursor 9 to the 8-methoxybenzo[f]indole-4,9-dione system 12 which incorporates the ABC ring syst

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2a24cc238f50ec71ae01f832637e3c89
https://doi.org/10.1002/chin.199137152

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ChemInform Abstract: Diversity of Reaction of Azoalkenes in Cycloadditions

Autor: George Ferguson, Donald Mackay, Alan J. Lough, Gamini Weeratunga

Publikováno v: ChemInform. 23

Reactions of the azoalkenes (E,E)-4-methyl-N-phenyl-2,3-diazapenta-2,4-diene-5-carboxamide 2 and methyl (E,Z)-3-methyl-4-phenylcarbamoyl-1,2-diazabuta-1,3-diene-1-carboxylate 3, having respectively an electron-rich and an electron-poor group on nitro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4c83e201a84286f77f44290d30ec48af
https://doi.org/10.1002/chin.199212061

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Regioselectivity in electrophilic substitution of 5-aminoindoles and 5-aminoindolines: synthesis of pyrrolo[3,2-e]indoles and isomeric pyrrolo[2,3-f]indoles

Autor: Ian Watts, Gamini Weeratunga, Ganesh K.B. Prasad, Gary I. Dmitrienko, Andrew Burchat

Publikováno v: Tetrahedron Letters. 32:5035-5038

An FMO Theory prediction that 5-aminoindoles, 5, should react with electrophiles preferentially at C4 rather than at C6 whereas N1-acyl-5-aminoindolines, 6, should react preferentially at C6 rather than C4 is borne out experimentally by the synthesis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9d7bdac55be081fc39a9845f2697dcd9
https://doi.org/10.1016/s0040-4039(00)93421-x

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N-cyanoindoles and n-cyanoindole-4,7-diones: Construction of a bc ring synthon for the kinamycins

Autor: Gary I. Dmitrienko, Christopher Steingart, Sai Ming Ngai, Jennifer M. Willson, Gamini Weeratunga, Kent E. Nielsen

Publikováno v: Tetrahedron Letters. 31:3681-3684

N-Cyano-2,3-dialkylindoles, available by reaction of N-sodioindoles with phenyl cyanate, are substantially less reactive than N-acylindoles under electrophilic bromination conditions but readily yield sidechain brominated products under free radical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::775ae61edf1759a9f93b3ddf34f6a09a
https://doi.org/10.1016/s0040-4039(00)97443-4

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Regioselective diels-alder reactions of n-cyanoindole-4,7-diones: Elaboration of the a-ring of the kinamycins on a bc ring template

Autor: John Dilley, Nicholas J. Taylor, Gamini Weeratunga, Ganesh K.B. Prasad, Gary I. Dmitrienko

Publikováno v: Tetrahedron Letters. 31:5713-5716

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5c7cf18f69068e8bc6ca8aae2123d29b
https://doi.org/10.1016/s0040-4039(00)97939-5

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