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Dynamic metabolism of endothelial triglycerides protects against atherosclerosis in mice.

Autor: Boutagy NE; Department of Pharmacology.; Vascular Biology and Therapeutics Program, and., Gamez-Mendez A; Department of Pharmacology.; Vascular Biology and Therapeutics Program, and., Fowler JW; Department of Pharmacology.; Vascular Biology and Therapeutics Program, and., Zhang H; Vascular Biology and Therapeutics Program, and.; Department of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut, USA., Chaube BK; Vascular Biology and Therapeutics Program, and.; Department of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut, USA., Esplugues E; Vascular Biology and Therapeutics Program, and.; Department of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut, USA., Kuo A; Vascular Biology Program, Department of Surgery, Boston Children's Hospital, Boston, Massachusetts, USA., Lee S; Department of Pharmacology.; Vascular Biology and Therapeutics Program, and., Horikami D; Department of Pharmacology.; Vascular Biology and Therapeutics Program, and., Zhang J; Department of Cardiology, Yale University School of Medicine, New Haven, Connecticut, USA., Citrin KM; Vascular Biology and Therapeutics Program, and.; Department of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut, USA., Singh AK; Department of Pharmacology.; Vascular Biology and Therapeutics Program, and., Coon BG; Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA.; Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA., Lee MY; Department of Physiology and Biophysics, Center for Cardiovascular Research, University of Illinois at Chicago School of Medicine, Chicago, Illinois, USA., Suarez Y; Vascular Biology and Therapeutics Program, and.; Department of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.; Department of Pathology, Yale University School of Medicine, New Haven, Connecticut, USA., Fernandez-Hernando C; Vascular Biology and Therapeutics Program, and.; Department of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.; Department of Pathology, Yale University School of Medicine, New Haven, Connecticut, USA., Sessa WC; Department of Pharmacology.; Vascular Biology and Therapeutics Program, and.; Department of Cardiology, Yale University School of Medicine, New Haven, Connecticut, USA.

Publikováno v: The Journal of clinical investigation [J Clin Invest] 2024 Jan 04; Vol. 134 (4). Date of Electronic Publication: 2024 Jan 04.

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Oxidative Stress-Dependent Coronary Endothelial Dysfunction in Obese Mice.

Autor: Ana María Gamez-Mendez, Hilda Vargas-Robles, Amelia Ríos, Bruno Escalante

Publikováno v: PLoS ONE, Vol 10, Iss 9, p e0138609 (2015)

Obesity is involved in several cardiovascular diseases including coronary artery disease and endothelial dysfunction. Endothelial Endothelium vasodilator and vasoconstrictor agonists play a key role in regulation of vascular tone. In this study, we e

Externí odkaz: https://doaj.org/article/cf232b12e8a34f57b87b78a807f465f2