Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Galyna P. Mrug"'
Publikováno v:
Chemistry of Natural Compounds. 57:9-13
The reactions of cytisine with glycidyl ethers of 3-arylcoumarins were studied. A series of cytisine–coumarin conjugates were synthesized via regiospecific opening of the oxirane ring by cytisine. Methods for conjugating anabasine and cytisine with
Autor:
David S. Watt, Thomas D. Hurley, Mykhaylo S. Frasinyuk, Peter J. Roach, Dyann M. Segvich, Krishna K. Mahalingan, Vimbai M. Chikwana, Cynthia A. Morgan, S. P. Bondarenko, Przemyslaw Wyrebek, Galyna P. Mrug, Anna A. DePaoli-Roach, Buyun Tang
Publikováno v:
J Med Chem
The over-accumulation of glycogen appears as a hallmark in various glycogen storage diseases (GSDs), including Pompe, Cori, Andersen and Lafora disease. Accumulating evidence suggests that suppression of glycogen accumulation represents a potential t
Autor:
Mykhaylo S. Frasinyuk, Iryna M. Biletska, Galyna P. Mrug, Yaroslav O. Prostota, Kostyantyn M. Kondratyuk, Svitlana P. Bondarenko
Publikováno v:
HETEROCYCLES. 104
Publikováno v:
Chemistry of Heterocyclic Compounds. 55:1179-1184
The transformations of 7-dimethylaminomethyl-6-hydroxyaurone and 5-dimethylaminomethyl-6-hydroxy-7-methylurone in the inversed electron-demand hetero-Diels–Alder reaction were studied. As a result of in situ thermal formation of o-quinone methides
Autor:
Svitlana P. Bondarenko, Mykhaylo S. Frasinyuk, Vitaliy M. Sviripa, Iryna M. Biletska, Galyna P. Mrug
Publikováno v:
ChemistrySelect. 4:11506-11510
Autor:
Mykhaylo S. Frasinyuk, Svitlana P. Bondarenko, Galyna P. Mrug, V. P. Khilya, Valentina I. Vinogradova
Publikováno v:
Chemistry of Natural Compounds. 55:628-631
The possibility of using the alkaloid anabasine in Mannich aminomethylation of coumarins was studied. Anabasine-coumarin conjugates in which the benzopyrone core was conjugated to anabasine through a methylene linker were synthesized.
Autor:
Svitlana P. Bondarenko, Mykhaylo S. Frasinyuk, B. A. Demidchuk, Galyna P. Mrug, N. V. Gorbulenko
Publikováno v:
Chemistry of Natural Compounds. 55:443-448
Reaction features of polyhydroxydeoxybenzoins and their heteroatomic analogs with succinic and glutaric anhydrides were studied and shown to be useful for synthesizing 3-(3-pyrazolyl)butyric acids and 4,11-dioxo-8,10,11,12-tetrahydro-4H,9H-pyrano[2,3
Autor:
V. P. Khilya, Svitlana P. Bondarenko, Galyna P. Mrug, Valentina I. Vinogradova, Mykhaylo S. Frasinyuk
Publikováno v:
Chemistry of Natural Compounds. 54:1068-1071
Possible Mannich aminomethylation of isoflavone chromone rings was studied using the alkaloid anabasine. Anabasine-isoflavone conjugates in which the benzopyrone core was connected to anabasine through a methylene linker were synthesized.
Autor:
Vitaliy M. Sviripa, David S. Watt, Svitlana P. Bondarenko, Galyna P. Mrug, Bohdan A. Demydchuk, James L. Mohler, Przemyslaw Wyrebek, Mykhaylo S. Frasinyuk, Michael V. Fiandalo, Chunming Liu
Publikováno v:
European Journal of Organic Chemistry. 2018:5460-5463
Publikováno v:
Chemistry of Natural Compounds. 54:660-664
Aminomethylation of the natural isoflavones afromosin and cladrastin and their 2-methyl derivatives was studied. Several new Mannich bases of 7-hydroxy-6-methoxyisoflavones were synthesized under Mannich reaction conditions using aminals of secondary