Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Galya Lerman"'
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107467 (2014)
The interaction between the immune system and epithelial cells is tightly regulated. Aberrations of this balance may result in inflammatory diseases such as psoriasis, inflammatory bowel disease and rheumatoid arthritis. IL-22 is produced by Th17, Th
Externí odkaz:
https://doaj.org/article/597c565bbddf4dab8b175c52a0a0c5ef
Autor:
Galya Lerman, Camila Avivi, Corine Mardoukh, Aviv Barzilai, Ariel Tessone, Ben Gradus, Felix Pavlotsky, Iris Barshack, Sylvie Polak-Charcon, Arie Orenstein, Eran Hornstein, Yechezkel Sidi, Dror Avni
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20916 (2011)
BackgroundPsoriasis is a complex disease at the cellular, genomic and genetic levels. The role of microRNAs in skin development was shown in a keratinocyte-specific Dicer knockout mouse model. Considering that two main characteristics of psoriasis ar
Externí odkaz:
https://doaj.org/article/d11cdfa76062413596cd7e07d4a2bce0
Autor:
Moran Penn, Daniel Rosenblum, Sushmita Chatterjee, Galya Lerman, Liyona Kampel, Anna Gutkin, Nidal Muhanna, Dan Peer, Nuphar Veiga, Meir Goldsmith, Srinivas Ramishetti
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 337
Currently there are no specific therapies addressing the distinctive biology of human papillomavirus (HPV)-induced cancer approved for clinical use. Short interfering RNA (siRNA) has much potential for therapeutic manipulation of HPV E6/E7 oncoprotei
Autor:
Dror Avni, Yechezkel Sidi, Joseph Kost, Moti Harats, Ramesh Chintakunta, Rinat Lifshiz Zimon, Tamar Traitel, Moamen Masalha, Etili Hollander, Riki Goldbart, Galya Lerman, Aviv Barzilai, Tal Meningher, Einat Elharrar
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 284
Psoriasis is a common, worldwide autoinflammatory, incurable skin disease. miR-197 has therapeutic potential for psoriasis since it can down-regulate the expression of both IL-22RA1 and IL-17RA, subunits of the receptors of IL-22 and IL-17, respectiv
Autor:
Oxana Kapitansky, Pinchas Gonen, Galya Lerman, Arielle R. Messer, Jean Albrengues, Shoshana Greenberger, Mehdi Khaled, Nira Amar, Carmit Levy, Tamar Golan, Aya Amitai-Lange, Ruby Shalom-Feuerstein, Yuval Tabach, Ze’ev Melamed, David Sprinzak, Rachel E. Bell, Cedric Gaggioli, Reut Ohana
Publikováno v:
Molecular Cell. 59(4):664-676
The most critical stage in initiation of melanoma metastasis is the radial to vertical growth transition, yet the triggers of this transition remain elusive. We suggest that the microenvironment drives melanoma metastasis independently of mutation ac
Autor:
Eli Schwartz, Tal Meningher, Galya Lerman, Yechezkel Sidi, Daniel Gold, Iddo Z. Ben-Dov, Dror Avni, Neta Regev-Rudzki
Publikováno v:
The Journal of infectious diseases. 215(3)
Background Schistosomiasis traditionally has been diagnosed by detecting eggs in stool or urine. However, the sensitivity of these examinations is limited, especially in travelers with a low worm burden. Serologic tests have a greater sensitivity, bu
Autor:
Riad Kassem, Dror Avni, Einat Elharrar, Moti Harats, Yechezkel Sidi, Moamen Masalha, Raya Leibowitz-Amit, Galya Lerman
Publikováno v:
Immunome Research. 12
Psoriasis is a chronic inflammatory skin disorder which results from pathological interactions between activated immunocytes and keratinocytes. Recent studies implicated the role of IL-17 and IL-22, secreted from Th17 and Th22 in the generation and p
Small-interfering RNA targeted at antiapoptotic mRNA increases keratinocyte sensitivity to apoptosis
Publikováno v:
British Journal of Dermatology. 164:947-956
Summary Background Gene silencing RNA interference technology concentrates on downregulation of gene expression using specific double-stranded RNA molecules (small-interfering RNA, siRNA), which induce the degradation of complementary mRNA. SiRNA the
Autor:
Dror Avni, Ben Gradus, Eran Hornstein, Corine Mardoukh, Arie Orenstein, Iris Barshack, Aviv Barzilai, Ariel Tessone, Galya Lerman, Sylvie Polak-Charcon, Camila Avivi, Yechezkel Sidi, Felix Pavlotsky
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20916 (2011)
PLoS ONE
PLoS ONE
BackgroundPsoriasis is a complex disease at the cellular, genomic and genetic levels. The role of microRNAs in skin development was shown in a keratinocyte-specific Dicer knockout mouse model. Considering that two main characteristics of psoriasis ar