Moderate Alcohol Drinking and the Amygdala Proteome: Identification and Validation of Calcium/Calmodulin Dependent Kinase II and AMPA Receptor Activity as Novel Molecular Mechanisms of the Positive Reinforcing Effects of Alcohol.

Autor: Salling MC; Departments of Curriculum in Neurobiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Faccidomo SP; Bowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Li C; Departments of Curriculum in Neurobiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Psilos K; Bowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Galunas C; Bowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Spanos M; Departments of Curriculum in Neurobiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Agoglia AE; Departments of Curriculum in Neurobiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Kash TL; Departments of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; Bowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; Departments of Curriculum in Neurobiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Hodge CW; Departments of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; Departments of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; Bowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; Departments of Curriculum in Neurobiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina. Electronic address: chodge@med.unc.edu.

Publikováno v: Biological psychiatry [Biol Psychiatry] 2016 Mar 15; Vol. 79 (6), pp. 430-42. Date of Electronic Publication: 2014 Oct 31.

Negative modulation of AMPA receptors bound to transmembrane AMPA receptor regulatory protein γ-8 blunts the positive reinforcing properties of alcohol and sucrose in a brain region-dependent manner in male mice.

Autor: Hoffman, Jessica L.¹ (AUTHOR), Faccidomo, Sara P.^1,2 (AUTHOR), Taylor, Seth M.¹ (AUTHOR), DeMiceli, Kristina G.¹ (AUTHOR), May, Ashley M.¹ (AUTHOR), Smith, Evan N.¹ (AUTHOR), Whindleton, Ciarra M.¹ (AUTHOR), Hodge, Clyde W.^1,2,3 (AUTHOR) chodge@med.unc.edu

Publikováno v: Psychopharmacology. Jun2023, Vol. 240 Issue 6, p1261-1273. 13p. 1 Diagram, 3 Graphs.

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A systematic review and meta-analysis on the transcriptomic signatures in alcohol use disorder.

Autor: Friske MM; Institute of Psychopharmacology, Central Institute of Mental Health, Mannheim, University of Heidelberg, Heidelberg, Germany. marion.friske@austin.utexas.edu.; Waggoner Center for Alcohol and Addiction Research and the Department of Neuroscience, The University of Texas at Austin, Austin, TX, USA. marion.friske@austin.utexas.edu., Torrico EC; Institute of Psychopharmacology, Central Institute of Mental Health, Mannheim, University of Heidelberg, Heidelberg, Germany., Haas MJW; Institute of Psychopharmacology, Central Institute of Mental Health, Mannheim, University of Heidelberg, Heidelberg, Germany., Borruto AM; Institute of Psychopharmacology, Central Institute of Mental Health, Mannheim, University of Heidelberg, Heidelberg, Germany., Giannone F; Institute of Psychopharmacology, Central Institute of Mental Health, Mannheim, University of Heidelberg, Heidelberg, Germany., Hade AC; Department of Pathological Anatomy and Forensic Medicine, University of Tartu, Tartu, Estonia.; Forensic Medical Examination Department, Estonian Forensic Science Institute, Tallinn, Estonia., Yu Y; Bioinformatics & Biostatistics Core, Oregon National Primate Research Center, Oregon Health & Science University West Campus, Portland, OR, USA., Gao L; Bioinformatics & Biostatistics Core, Oregon National Primate Research Center, Oregon Health & Science University West Campus, Portland, OR, USA., Sutherland GT; New South Wales Tissue Resource Center, University of Sydney, Camperdown, NSW, Australia., Hitzemann R; Department of Behavioral Neuroscience, Oregon Health & Science University, Portland, OR, USA., Philips MA; Department of Physiology, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia., Fei SS; Bioinformatics & Biostatistics Core, Oregon National Primate Research Center, Oregon Health & Science University West Campus, Portland, OR, USA., Sommer WH; Bethania Hospital for Psychiatry, Psychosomatics and Psychotherapy, Greifswald, Germany.; German Center for Mental Health (DZPG), Partner Site Mannheim-Heidelberg-Ulm, Mannheim, Germany., Mayfield RD; Waggoner Center for Alcohol and Addiction Research and the Department of Neuroscience, The University of Texas at Austin, Austin, TX, USA., Spanagel R; Institute of Psychopharmacology, Central Institute of Mental Health, Mannheim, University of Heidelberg, Heidelberg, Germany. rainer.spanagel@zi-mannheim.de.; German Center for Mental Health (DZPG), Partner Site Mannheim-Heidelberg-Ulm, Mannheim, Germany. rainer.spanagel@zi-mannheim.de.

Publikováno v: Molecular psychiatry [Mol Psychiatry] 2025 Jan; Vol. 30 (1), pp. 310-326. Date of Electronic Publication: 2024 Sep 06.

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