Single-cell transcriptomics of pediatric Burkitt lymphoma reveals intra-tumor heterogeneity and markers of therapy resistance.

Autor: Corinaldesi C; Institute for Cancer Genetics, Columbia University, New York, NY, USA., Holmes AB; Institute for Cancer Genetics, Columbia University, New York, NY, USA., Martire G; Maternal and Child Health Department, University-Hospital of Padova, Padova, Italy.; Istituto di Ricerca Pediatrica Citta' della Speranza, Padova, Italy., Tosato A; Institute for Cancer Genetics, Columbia University, New York, NY, USA.; Maternal and Child Health Department, University-Hospital of Padova, Padova, Italy.; Istituto di Ricerca Pediatrica Citta' della Speranza, Padova, Italy., Rizzato D; Maternal and Child Health Department, University-Hospital of Padova, Padova, Italy., Lovisa F; Istituto di Ricerca Pediatrica Citta' della Speranza, Padova, Italy., Gallingani I; Maternal and Child Health Department, University-Hospital of Padova, Padova, Italy.; Istituto di Ricerca Pediatrica Citta' della Speranza, Padova, Italy., Shen Q; Institute for Cancer Genetics, Columbia University, New York, NY, USA., Ferrone L; Maternal and Child Health Department, University-Hospital of Padova, Padova, Italy.; Istituto di Ricerca Pediatrica Citta' della Speranza, Padova, Italy., Harris M; Department of Pathology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Davies K; Dana-Farber Cancer Institute, Boston, MA, USA., Molinaro L; Department of Medical Science, University of Torino, Torino, Italy., Mortara U; Department of Medical Science, University of Torino, Torino, Italy., Dei Tos AP; General Pathology and Cytopathology Unit, Department of Medicine-DMED, University-Hospital of Padova, Padova, Italy., Ofori K; Department of Pathology & Cell Biology, Columbia University, New York, NY, USA., D'Amore ESG; Department of Pathology, San Bortolo Hospital, Vicenza, Italy., Chiarle R; Department of Pathology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy.; European Institute of Oncology IRCCS, Division of Hematopathology, Milan, Italy., Ngan B; Hospital for Sick Children (SickKids), Toronto, ON, Canada., Carraro E; Maternal and Child Health Department, University-Hospital of Padova, Padova, Italy., Pillon M; Maternal and Child Health Department, University-Hospital of Padova, Padova, Italy., Hussein S; Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Bhagat G; Department of Pathology & Cell Biology, Columbia University, New York, NY, USA.; Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA., Pizzi M; General Pathology and Cytopathology Unit, Department of Medicine-DMED, University-Hospital of Padova, Padova, Italy., Mussolin L; Maternal and Child Health Department, University-Hospital of Padova, Padova, Italy. lara.mussolin@unipd.it.; Istituto di Ricerca Pediatrica Citta' della Speranza, Padova, Italy. lara.mussolin@unipd.it., Basso K; Institute for Cancer Genetics, Columbia University, New York, NY, USA. kb451@cumc.columbia.edu.; Department of Pathology & Cell Biology, Columbia University, New York, NY, USA. kb451@cumc.columbia.edu.

Publikováno v: Leukemia [Leukemia] 2024 Oct 18. Date of Electronic Publication: 2024 Oct 18.

Plasma small-extracellular vesicles enriched in miR-122-5p promote disease aggressiveness in pediatric anaplastic large-cell lymphoma.

Autor: Damanti CC; Maternal and Child Health Department Pediatric Hematology, Oncology and Stem Cell Transplant Center, University of Padua, Padua, Italy.; Pediatric Research Institute 'Città della Speranza', Padua, Italy., Ferrone L; Maternal and Child Health Department Pediatric Hematology, Oncology and Stem Cell Transplant Center, University of Padua, Padua, Italy.; Pediatric Research Institute 'Città della Speranza', Padua, Italy.; Department of Biomedical Sciences, University of Padua, Padua, Italy., Gaffo E; Department of Molecular Medicine, University of Padua, Padua, Italy., Garbin A; Maternal and Child Health Department Pediatric Hematology, Oncology and Stem Cell Transplant Center, University of Padua, Padua, Italy.; Pediatric Research Institute 'Città della Speranza', Padua, Italy., Tosato A; Maternal and Child Health Department Pediatric Hematology, Oncology and Stem Cell Transplant Center, University of Padua, Padua, Italy.; Pediatric Research Institute 'Città della Speranza', Padua, Italy., Contarini G; Maternal and Child Health Department Pediatric Hematology, Oncology and Stem Cell Transplant Center, University of Padua, Padua, Italy.; Pediatric Research Institute 'Città della Speranza', Padua, Italy., Gallingani I; Maternal and Child Health Department Pediatric Hematology, Oncology and Stem Cell Transplant Center, University of Padua, Padua, Italy.; Pediatric Research Institute 'Città della Speranza', Padua, Italy., Angioni R; Pediatric Research Institute 'Città della Speranza', Padua, Italy.; Department of Biomedical Sciences, University of Padua, Padua, Italy., Molon B; Pediatric Research Institute 'Città della Speranza', Padua, Italy.; Department of Biomedical Sciences, University of Padua, Padua, Italy., Borile G; Pediatric Research Institute 'Città della Speranza', Padua, Italy., Carraro E; Maternal and Child Health Department Pediatric Hematology, Oncology and Stem Cell Transplant Center, University of Padua, Padua, Italy., Pillon M; Maternal and Child Health Department Pediatric Hematology, Oncology and Stem Cell Transplant Center, University of Padua, Padua, Italy., Scarmozzino F; General Pathology and Cytopathology Unit, Department of Medicine-DMED, University of Padua, Padua, Italy., Dei Tos AP; General Pathology and Cytopathology Unit, Department of Medicine-DMED, University of Padua, Padua, Italy., Pizzi M; General Pathology and Cytopathology Unit, Department of Medicine-DMED, University of Padua, Padua, Italy., Ciscato F; Department of Biomedical Sciences, University of Padua, Padua, Italy., Rasola A; Department of Biomedical Sciences, University of Padua, Padua, Italy., Biffi A; Maternal and Child Health Department Pediatric Hematology, Oncology and Stem Cell Transplant Center, University of Padua, Padua, Italy.; Pediatric Research Institute 'Città della Speranza', Padua, Italy., Bortoluzzi S; Department of Molecular Medicine, University of Padua, Padua, Italy., Lovisa F; Maternal and Child Health Department Pediatric Hematology, Oncology and Stem Cell Transplant Center, University of Padua, Padua, Italy.; Pediatric Research Institute 'Città della Speranza', Padua, Italy., Mussolin L; Maternal and Child Health Department Pediatric Hematology, Oncology and Stem Cell Transplant Center, University of Padua, Padua, Italy.; Pediatric Research Institute 'Città della Speranza', Padua, Italy.

Publikováno v: Cancer communications (London, England) [Cancer Commun (Lond)] 2023 May; Vol. 43 (5), pp. 630-634. Date of Electronic Publication: 2023 Apr 04.

069 - MiR-146a-5p IS ENRICHED IN PLASMA SMALL EXTRACELLULAR VESICLES OF PEDIATRIC ALCL PATIENTS WITH POOR PROGNOSIS AND HAS A ROLE IN MACROPHAGE POLARIZATION

Autor: Garbin, A., Damanti, C., Lovisa, F., Gaffo, E., Gallingani, I., Ferrone, L., Tosato, A., Contarini, G., Carraro, E., Pillon, M., Bortoluzzi, S., Biffi, A., Mussolin, L.

Publikováno v: In Leukemia Research October 2022 121 Supplement:S47-S47

029 - SINGLE-CELL TRANSCRIPTOMIC ANALYSIS OF PEDIATRIC BURKITT LYMPHOMA REVEALS INTRA-TUMOR HETEROGENEITY

Autor: Corinaldesi, C., Gallingani, I., Holmes, A., Lovisa, F., Carraro, E., Pillon, M., Dalla-Favera, R., Basso, K., Mussolin, L.

Publikováno v: In Leukemia Research October 2022 121 Supplement:S22-S23

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