Activation of the Ghrelin Receptor is Described by a Privileged Collective Motion: A Model for Constitutive and Agonist-induced Activation of a Sub-class A G-Protein Coupled Receptor (GPCR)

Autor: Floquet, Nicolas, M'Kadmi, Céline, Perahia, David, Gagne, Didier, Bergé, Gilbert, Marie, Jacky, Banères, Jean-Louis, Galleyrand, Jean-Claude, Fehrentz, Jean-Alain, Martinez, Jean

Publikováno v: In Journal of Molecular Biology 2010 395(4):769-784

Cross-interactions of Two p38 Mitogen-activated Protein (MAP) Kinase Inhibitors and Two Cholecystokinin (CCK) Receptor Antagonists with the CCK1 Receptor and P38 MAP Kinase

Autor: Morel, Caroline, Ibarz, Géraldine, Oiry, Catherine, Carnazzi, Eric, Bergé, Gilbert, Gagne, Didier, Galleyrand, Jean-Claude ^‡, Martinez, Jean

Publikováno v: In Journal of Biological Chemistry 3 June 2005 280(22):21384-21393

The novel nonapeptide acein targets angiotensin converting enzyme in the brain and induces dopamine release

Autor: Neasta, Jérémie, Valmalle, Charlène, Coyne, Anne‐Claire, Carnazzi, Eric, Subra, Gilles, Galleyrand, Jean‐Claude, Gagne, Didier, M'Kadmi, Céline, Bernad, Nicole, Bergé, Gilbert, Cantel, Sonia, Marin, Philippe, Marie, Jacky, Banères, Jean‐Louis, Kemel, Marie‐Lou, Daugé, Valérie, Puget, Karine, Martinez, Jean

Publikováno v: British Journal of Pharmacology
British Journal of Pharmacology, Wiley, 2016, 173 (8), pp.1314--28. ⟨10.1111/bph.13424⟩
British Journal of Pharmacology, 2016, 173 (8), pp.1314--28. ⟨10.1111/bph.13424⟩

International audience; Background and PurposeUsing an in-house bioinformatics programme, we identified and synthesized a novel nonapeptide, H-Pro-Pro-Thr-Thr-Thr-Lys-Phe-Ala-Ala-OH. Here, we have studied its biological activity, in vitro and in vivo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9b0e486086ba92b21fd8ed295520fe01
https://hal.archives-ouvertes.fr/hal-01942451

Study of a lipophilic captopril analogue binding to angiotensin I converting enzyme

Autor: A. Dalkas, Georgios, Marchand, Damien, Galleyrand, Jean-Claude, Martinez, Jean, A. Spyroulias, Georgios, Cordopatis, Paul, Cavelier, Florine

Publikováno v: Journal of Peptide Science
Journal of Peptide Science, Wiley, 2010, 16, pp.91-97. ⟨10.1002/psc.1201⟩

International audience; HumanACE is a central component of the renin–angiotensin systemand amajor therapeutic target for cardiovascular diseases. The somatic form of the enzyme (sACE) comprises two homologous metallopeptidase domains (N and C), eac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a003c28a2b5c5bbd9867c165c3e528c6
https://hal.archives-ouvertes.fr/hal-00449420

Ghrelin ligands : from design and synthesis to clinical studies

Autor: Fehrentz, Jean-Alain, Demange, Luc, Moulin, Aline, Guerlavais, V., Boeglin, D., Mousseaux, D., Ryan, Joanne, Gagne, Didier, Bergé, G., Gozé, C., Galleyrand, Jean-Claude, Perissoud, Daniel, Martinez, Jean

Publikováno v: 43èmes Rencontres Internationales de Chimie Thérapeutiques
43èmes Rencontres Internationales de Chimie Thérapeutiques, Jul 2007, Lille, France

National audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::83ba98f82825cc4c6c007a97c9aac639
https://hal.archives-ouvertes.fr/hal-00346161