Immunotherapy with engineered bacteria by targeting the STING pathway for anti-tumor immunity.

Autor: Leventhal DS; Synlogic, Inc., 301 Binney street, suite 402, Cambridge, Massachusetts, 02142, United States. dleventhal@uchicago.edu., Sokolovska A; Synlogic, Inc., 301 Binney street, suite 402, Cambridge, Massachusetts, 02142, United States. anna@synlogictx.com., Li N; Synlogic, Inc., 301 Binney street, suite 402, Cambridge, Massachusetts, 02142, United States., Plescia C; Synlogic, Inc., 301 Binney street, suite 402, Cambridge, Massachusetts, 02142, United States., Kolodziej SA; Synlogic, Inc., 301 Binney street, suite 402, Cambridge, Massachusetts, 02142, United States., Gallant CW; Synlogic, Inc., 301 Binney street, suite 402, Cambridge, Massachusetts, 02142, United States., Christmas R; Synlogic, Inc., 301 Binney street, suite 402, Cambridge, Massachusetts, 02142, United States., Gao JR; Synlogic, Inc., 301 Binney street, suite 402, Cambridge, Massachusetts, 02142, United States., James MJ; Synlogic, Inc., 301 Binney street, suite 402, Cambridge, Massachusetts, 02142, United States., Abin-Fuentes A; Synlogic, Inc., 301 Binney street, suite 402, Cambridge, Massachusetts, 02142, United States., Momin M; Synlogic, Inc., 301 Binney street, suite 402, Cambridge, Massachusetts, 02142, United States., Bergeron C; Synlogic, Inc., 301 Binney street, suite 402, Cambridge, Massachusetts, 02142, United States., Fisher A; Synlogic, Inc., 301 Binney street, suite 402, Cambridge, Massachusetts, 02142, United States., Miller PF; Synlogic, Inc., 301 Binney street, suite 402, Cambridge, Massachusetts, 02142, United States., West KA; Synlogic, Inc., 301 Binney street, suite 402, Cambridge, Massachusetts, 02142, United States., Lora JM; Synlogic, Inc., 301 Binney street, suite 402, Cambridge, Massachusetts, 02142, United States. jlora@engene.com.

Publikováno v: Nature communications [Nat Commun] 2020 Jun 01; Vol. 11 (1), pp. 2739. Date of Electronic Publication: 2020 Jun 01.