Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Galit Elad‐Sfadia"'
Autor:
Morad Zayoud, Einav Vax, Galit Elad‐Sfadia, Iris Barshack, Ronit Pinkas‐Kramarski, Itamar Goldstein
Publikováno v:
ACR Open Rheumatology, Vol 2, Iss 9, Pp 512-524 (2020)
Objective RasGTPases are master regulators of multiple intracellular signaling cascades. Perturbation of this pathway has been implicated in the pathogenesis of rheumatoid arthritis (RA). In this study we aimed to define the therapeutic potential of
Externí odkaz:
https://doaj.org/article/77f93c51061c4b679acab29fe3df78f8
Autor:
Morad Zayoud, Victoria Marcu-Malina, Einav Vax, Jasmine Jacob-Hirsch, Galit Elad-Sfadia, Iris Barshack, Yoel Kloog, Itamar Goldstein
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
The Ras family of GTPases plays an important role in signaling nodes downstream to T cell receptor and CD28 activation, potentially lowering the threshold for T-cell receptor activation by autoantigens. Somatic mutation in NRAS or KRAS may cause a ra
Externí odkaz:
https://doaj.org/article/b38a5c37db0144778b6064454b2ed559
Autor:
Ariel Nir Sade, Gilad Levy, Sari Schokoroy Trangle, Galit Elad Sfadia, Ela Bar, Omer Ophir, Inbar Fischer, May Rokach, Andrea Atzmon, Hadar Parnas, Tali Rosenberg, Asaf Marco, Orna Elroy Stein, Boaz Barak
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
Abstract Gtf2i encodes the general transcription factor II-I (TFII-I), with peak expression during pre-natal and early post-natal brain development stages. Because these stages are critical for proper brain development, we studied at the single-cell
Externí odkaz:
https://doaj.org/article/4f6a8d1486f84e14ae32d70a925fdfed
Autor:
Yoram Nevo, Shlomit Aga-Mizrachi, Edva Elmakayes, Nurit Yanay, Keren Ettinger, Moran Elbaz, Zivia Brunschwig, Oshrat Dadush, Galit Elad-Sfadia, Roni Haklai, Yoel Kloog, Joab Chapman, Shimon Reif
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e18049 (2011)
The Ras superfamily of guanosine-triphosphate (GTP)-binding proteins regulates a diverse spectrum of intracellular processes involved in inflammation and fibrosis. Farnesythiosalicylic acid (FTS) is a unique and potent Ras inhibitor which decreased i
Externí odkaz:
https://doaj.org/article/3e0e0395acd2471d8f1ed6eb1990aded
Autor:
Omer Ophir, Gilad Levy, Ela Bar, Omri Kimchi Feldhorn, May Rokach, Galit Elad Sfadia, Boaz Barak
Publikováno v:
Biomedicines, Vol 11, Iss 8, p 2273 (2023)
Williams syndrome (WS) is a neurodevelopmental disorder characterized by distinctive cognitive and personality profiles which also impacts various physiological systems. The syndrome arises from the deletion of about 25 genes located on chromosome 7q
Externí odkaz:
https://doaj.org/article/7598d15b0fcd4806b1dfb7db76302c1f
Autor:
Galit Elad-Sfadia, Itamar Goldstein, Iris Barshack, Einav Vax, Ronit Pinkas-Kramarski, Morad Zayoud
Publikováno v:
ACR Open Rheumatology, Vol 2, Iss 9, Pp 512-524 (2020)
Objective RasGTPases are master regulators of multiple intracellular signaling cascades. Perturbation of this pathway has been implicated in the pathogenesis of rheumatoid arthritis (RA). In this study we aimed to define the therapeutic potential of
Autor:
Osnat Sher, Adi Porat-Klein, Shifra Ash, Galit Elad-Sfadia, Isaac Yaniv, Smadar Avigad, Elena Chepurko, Yona Kodman, Yehuda Kollender, Michal Hameiri-Grossman, Ian J. Cohen, Drorit Luria, Yoel Kloog, Josephine Issakov, Ronit Haklai, Avraham Weizman, Meora Feinmesser
Publikováno v:
Oncotarget
Ewing Sarcoma (ES) is the second most common primary malignant bone tumor in children and adolescents. microRNAs (miRNAs) are involved in cancer as tumor suppressors or oncogenes. We studied the involvement of miRNAs located on chromosomes 11q and 22
Autor:
Shimon Reif, Efrat Sharvit, Galit Elad-Sfadia, Shirley Abramovitch, Yoel Kloog, Rina Neeman, Roni Haklai
Publikováno v:
Digestive Diseases and Sciences. 59:2462-2469
Hepatic stellate cells (HSCs) have a key role in the formation of hepatic fibrosis. The active form of vitamin D, 1,25(OH)2D3, has been found to have antiproliferative and antifibrotic effects in various tissues including liver. Farnesylthiosalicylic
Autor:
Eya Wolfson, Galit Elad-Sfadia, Yoel Kloog, Roni Haklai, Ronit Pinkas-Kramarski, Eran Schmukler
Publikováno v:
Oncotarget
// Eran Schmukler 1 , Eya Wolfson 1 , Roni Haklai 1 , Galit Elad-Sfadia 1 , Yoel Kloog 1 and Ronit Pinkas-Kramarski 1 1 Department of Neurobiology. Tel-Aviv University, Ramat-Aviv, Israel. Correspondence: Ronit Pinkas-Kramarski, email: // Keywords :
Autor:
Efrat Mashiach-Farkash, Shmuel Carmeli, Galit Elad-Sfadia, Haim J. Wolfson, Yoel Kloog, Roni Haklai, Roni Rak
Publikováno v:
Oncotarget
Efrat Mashiach-Farkash *,1 , Roni Rak *,3 , Galit Elad-Sfadia 3 , Roni Haklai 3 , Shmuel Carmeli 2 , Yoel Kloog 3 and Haim J. Wolfson 1 1 The Blavatnik School of Computer Science, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel-Aviv Univer