Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Galini Thoidis"'
Autor:
Petr O Ilyinskii, Alexandra S Gambaryan, Anatoli B Meriin, Vladimir Gabai, Alex Kartashov, Galini Thoidis, Alexander M Shneider
Publikováno v:
PLoS ONE, Vol 3, Iss 1, p e1417 (2008)
The effectiveness of recombinant vaccines encoding full-length M2 protein of influenza virus or its ectodomain (M2e) have previously been tested in a number of models with varying degrees of success. Recently, we reported a strong cytotoxic effect ex
Externí odkaz:
https://doaj.org/article/351ed22ba3b9498dbfac0dcdefe12304
Publikováno v:
Vaccine. 26:3223-3226
Aggregation may significantly affect the fate of a polypeptide, including its susceptibility to proteasome-dependent or autophagic degradation, its interaction with chaperones, etc. Since all these factors may affect the antigenicity of a polypeptide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ff5fd5919d571ee2564a772403911a1
https://doi.org/10.1016/j.vaccine.2008.03.078
https://doi.org/10.1016/j.vaccine.2008.03.078
Autor:
Galini Thoidis, Konstantin V. Kandror
Publikováno v:
Traffic. 2:577-587
Glut4-containing vesicles represent a regulated recycling compartment in insulin-sensitive fat and skeletal muscle cells, the nature and origin of which are not fully understood. In addition to Glut4 itself, these vesicles compartmentalize a number o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32ac1ab458dfad6923092da6b7fb60e7
https://doi.org/10.1034/j.1600-0854.2001.20807.x
https://doi.org/10.1034/j.1600-0854.2001.20807.x
Autor:
Galini Thoidis, Paul F. Pilch, Manuel Palacín, Xavier Testar, Antonio Zorzano, Mario Rosemblatt, Purificación Muñoz
Publikováno v:
Biochemical Journal. 312:393-400
(1) In this study we have determined the distribution of various membrane proteins involved in insulin-activated glucose transport in T-tubules and in sarcolemma from rat skeletal muscle. Two independent experimental approaches were used to determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::685e514e6bd5227637329c3e40f5949f
https://doi.org/10.1042/bj3120393
https://doi.org/10.1042/bj3120393
Publikováno v:
Journal of Biological Chemistry. 268:11691-11696
In adipocytes and muscle, insulin stimulates the translocation of glucose transporter proteins from an intracellular vesicle pool to the plasma membrane. To study the molecular basis of this process, we used the anti-GLUT4 antibody 1F8 to isolate int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6638e101e77a24ed2de6fdf800eb5e93
https://doi.org/10.1016/s0021-9258(19)50255-1
https://doi.org/10.1016/s0021-9258(19)50255-1
Autor:
Anatoli B. Meriin, Alexander M. Shneider, Dmitrij Frishman, Petr O. Ilyinskii, Dmitry Lukashev, Thorsten Schmidt, Galini Thoidis
Publikováno v:
Omics : a journal of integrative biology. 13(5)
Development of novel vaccines and therapeutics often requires efficient expression of recombinant viral proteins. Here we show that mutations in essential functional regions of conserved influenza proteins NP and NS1, lead to reduced expression of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06582917f1467c9b1619a09e22748ba3
https://pubmed.ncbi.nlm.nih.gov/19594376
https://pubmed.ncbi.nlm.nih.gov/19594376
Autor:
Alexander M. Shneider, Alexei G. Prilipov, Petr O. Ilyinskii, Maria Nurminskaya, Anatoly D. Altstein, Galini Thoidis, Vladimir L. Gabai, Lyudmila G. Zakharova, Evgeny V. Usachev
Publikováno v:
Omics : a journal of integrative biology. 13(3)
Inadvertent cytotoxicity may hinder the expression of many recombinant proteins that are of industrial or medicinal importance. Here, we show that covalent binding of the influenza A cytotoxic protein M2 to a polyglutamine domain (polyQ-M2; QM2) resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff51fd052f9a41e1127da05450af933f
https://pubmed.ncbi.nlm.nih.gov/19441878
https://pubmed.ncbi.nlm.nih.gov/19441878
Publikováno v:
International reviews of immunology. 27(6)
The constant threat of a new influenza pandemic, which may be caused by a highly pathogenic avian influenza virus, necessitates the development of a vaccine capable of providing efficient, long-term, and cost-effective protection. Proven avenues for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89d6835e0932b8f64354388a069a8db4
https://pubmed.ncbi.nlm.nih.gov/19065349
https://pubmed.ncbi.nlm.nih.gov/19065349
Autor:
Vladimir L. Gabai, Anatoli B. Meriin, Petr O. Ilyinskii, Alexei G. Prilipov, Evgeny V. Usachev, Galini Thoidis, Alexander M. Shneider
Publikováno v:
Protein science : a publication of the Protein Society. 17(6)
It is assumed that the proteosome-processing characteristics of fusion constructs can be predicted from the sum of the proteosome sensitivity of their components. In the present study, we observed that a fusion construct consisting of proteosome-degr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::289594f8ae370657b062f1cf448a0329
https://pubmed.ncbi.nlm.nih.gov/18411420
https://pubmed.ncbi.nlm.nih.gov/18411420
Autor:
Petr O. Ilyinskii, Oleg P. Zhirnov, Vladimir L. Gabai, Anatoli B. Meriin, Galini Thoidis, Alexander M. Shneider
Publikováno v:
Vaccine
Summary Targeting viral antigens for proteosomal degradation has previously been proposed as a means for immunogenicity augmentation. However, utilization of modified unstable antigens may be insufficient for potent T-cell cross-presentation by APCs,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::123bc53c2294a1a57d0a8563cba5ac48
https://europepmc.org/articles/PMC2440663/
https://europepmc.org/articles/PMC2440663/
