Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Galina V. Petukhova"'
Autor:
Ondrej Mihola, Vladimir Landa, Florencia Pratto, Kevin Brick, Tatyana Kobets, Fitore Kusari, Srdjan Gasic, Fatima Smagulova, Corinne Grey, Petr Flachs, Vaclav Gergelits, Karel Tresnak, Jan Silhavy, Petr Mlejnek, R. Daniel Camerini-Otero, Michal Pravenec, Galina V. Petukhova, Zdenek Trachtulec
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-20 (2021)
Abstract Background Vertebrate meiotic recombination events are concentrated in regions (hotspots) that display open chromatin marks, such as trimethylation of lysines 4 and 36 of histone 3 (H3K4me3 and H3K36me3). Mouse and human PRDM9 proteins catal
Externí odkaz:
https://doaj.org/article/03a0d82fd99840bf996152ad7bf19c03
Autor:
Vladimír Landa, Fatima Smagulova, Florencia Pratto, Ondrej Mihola, Michal Pravenec, Srdjan Gasic, R. Daniel Camerini-Otero, Petr Flachs, Corinne Grey, Fitore Kusari, Karel Tresnak, Vaclav Gergelits, Galina V. Petukhova, Petr Mlejnek, Zdenek Trachtulec, Tatyana Kobets, Kevin Brick, Jan Silhavy
Publikováno v:
BMC Biology
BMC Biology, Vol 19, Iss 1, Pp 1-20 (2021)
BMC Biology, 2021, 19 (1), pp.86. ⟨10.1186/s12915-021-01017-0⟩
BMC Biology, BioMed Central, 2021, 19 (1), pp.86. ⟨10.1186/s12915-021-01017-0⟩
BMC Biology, Vol 19, Iss 1, Pp 1-20 (2021)
BMC Biology, 2021, 19 (1), pp.86. ⟨10.1186/s12915-021-01017-0⟩
BMC Biology, BioMed Central, 2021, 19 (1), pp.86. ⟨10.1186/s12915-021-01017-0⟩
BackgroundVertebrate meiotic recombination events are concentrated in regions (hotspots) that display open chromatin marks, such as trimethylation of lysines 4 and 36 of histone 3 (H3K4me3 and H3K36me3). Mouse and human PRDM9 proteins catalyze H3K4me
Publikováno v:
Methods in Enzymology ISBN: 9780128139790
The repair of programmed DNA double-strand breaks (DSBs) physically tethers homologous chromosomes in meiosis to allow for accurate segregation through meiotic cell divisions. This process, known as recombination, also results in the exchange of alle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e4ff08dce2d700d6320a031fb160c90
https://doi.org/10.1016/bs.mie.2017.11.037
https://doi.org/10.1016/bs.mie.2017.11.037
Autor:
Kevin Brick, R. Daniel Camerini-Otero, Fatima Smagulova, Florencia Pratto, Sarah Thibault-Sennett, Kwan-Wood Gabriel Lam, Yongmei Pu, Galina V. Petukhova
Publikováno v:
Nature
Nature, 2018, 561 (7723), pp.338-+. ⟨10.1038/s41586-018-0492-5⟩
Nature, Nature Publishing Group, 2018, 561 (7723), pp.338-+. ⟨10.1038/s41586-018-0492-5⟩
Nature, 2018, 561 (7723), pp.338-+. ⟨10.1038/s41586-018-0492-5⟩
Nature, Nature Publishing Group, 2018, 561 (7723), pp.338-+. ⟨10.1038/s41586-018-0492-5⟩
International audience; Meiotic recombination differs between males and females; however, when and how these differences are established is unknown. Here we identify extensive sex differences at the initiation of recombination by mapping hotspots of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e5ac2849a0bb1aa4fdc603dd6e1408b
https://doi.org/10.1101/235002
https://doi.org/10.1101/235002
Meiotic recombination is required for the segregation of homologous chromosomes and is essential for fertility. In most mammals, the DNA double-strand breaks (DSBs) that initiate meiotic recombination are directed to a subset of genomic loci (hot spo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::634a63c45276c1d8361021cee896d995
https://europepmc.org/articles/PMC4826402/
https://europepmc.org/articles/PMC4826402/
Publikováno v:
Genes and Development
Genes and Development, Cold Spring Harbor Laboratory Press, 2016, 30 (3), pp.266--280. ⟨10.1101/gad.270009.115⟩
Genes and Development, 2016, 30 (3), pp.266--280. ⟨10.1101/gad.270009.115⟩
Genes and Development, Cold Spring Harbor Laboratory Press, 2016, 30 (3), pp.266--280. ⟨10.1101/gad.270009.115⟩
Genes and Development, 2016, 30 (3), pp.266--280. ⟨10.1101/gad.270009.115⟩
Meiotic recombination is required for the segregation of homologous chromosomes and is essential for fertility. In most mammals, the DNA double-strand breaks (DSBs) that initiate meiotic recombination are directed to a subset of genomic loci (hot spo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c67f21e2af3aed5dcce45fbf44ab72
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01281480
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01281480
Autor:
Ugo Déry, R. Daniel Camerini-Otero, Galina V. Petukhova, Ali Bransi, Dany Morneau, Jean-Yves Masson, Andrzej Stasiak, Mickaël Ploquin
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, vol. 35, no. 8, pp. 2719-2733
Nucleic Acids Research, vol. 35, no. 8, pp. 2719-2733
Genetic analysis of fission yeast suggests a role for the spHop2-Mnd1 proteins in the Rad51 and Dmc1-dependent meiotic recombination pathways. In order to gain biochemical insights into this process, we purified Schizosaccharomyces pombe Hop2-Mnd1 to
Autor:
Florencia, Pratto, Kevin, Brick, Pavel, Khil, Fatima, Smagulova, Galina V, Petukhova, R Daniel, Camerini-Otero
Publikováno v:
Science (New York, N.Y.). 346(6211)
DNA double-strand breaks (DSBs) are introduced in meiosis to initiate recombination and generate crossovers, the reciprocal exchanges of genetic material between parental chromosomes. Here, we present high-resolution maps of meiotic DSBs in individua
Autor:
Kevin Brick, Pavel P. Khil, R. Daniel Camerini-Otero, Fatima Smagulova, Florencia Pratto, Galina V. Petukhova
Publikováno v:
Science. 346
DNA double-strand breaks (DSBs) are introduced in meiosis to initiate recombination and generate crossovers, the reciprocal exchanges of genetic material between parental chromosomes. Here, we present high-resolution maps of meiotic DSBs in individua
Autor:
Michael J. Kruhlak, Oscar Fernandez-Capetillo, R. Daniel Camerini-Otero, Hua-Tang Chen, Yongping Yang, Bernardo Reina San Martin, Michel C. Nussenzweig, Lionel Feigenbaum, Simone Difilippantonio, Arkady Celeste, Galina V. Petukhova, André Nussenzweig, François Van Laethem, Shyam K. Sharan, Katia Manova, Michael Eckhaus
Publikováno v:
Nature Cell Biology. 7:675-685
Nijmegen breakage syndrome (NBS) is a chromosomal fragility disorder that shares clinical and cellular features with ataxia telangiectasia. Here we demonstrate that Nbs1-null B cells are defective in the activation of ataxia-telangiectasia-mutated (A