Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Galina V. Pazynina"'
Autor:
Galina V. Pazynina, Svetlana V. Tsygankova, Marina A. Sablina, Nadezhda V. Shilova, Alexander S. Paramonov, Alexander O. Chizhov, Nicolai V. Bovin
Publikováno v:
Mendeleev Communications. 33:107-108
Autor:
Elena V. Gavrilova, Rinat A. Maksyutov, Nicolai V. Bovin, Alexandr B. Ryzhikov, Galina V. Pazynina, Galina S. Onkhonova, Ivan M. Ryzhov, Ilnaz R. Imatdinov, E. A. Gordeeva, Nadezhda Shilova
Publikováno v:
Biochemistry. Biokhimiia
Many viruses, beside binding to their main cell target, interact with other molecules that promote virus adhesion to the cell; often, these additional targets are glycans. The main receptor for SARS-CoV-2 is a peptide motif in the ACE2 protein. We st
Autor:
Sergey V. Khaidukov, Svetlana V. Tsygankova, Eugenia M. Rapoport, Nicolai V. Bovin, Kenneth C. McCullough, E.V. Moiseeva, Galina V. Pazynina, Ivan M. Belyanchikov, Tatiana V. Tyrtysh, Ivan M. Ryzhov, D.A. Aronov
Publikováno v:
Glycoconjugate Journal. 37:129-138
Modification of vaccine carriers by decoration with glycans can enhance binding to and even targeting of dendritic cells (DCs), thus augmenting vaccine efficacy. To find a specific glycan-“vector” it is necessary to know glycan-binding profile of
Autor:
Polina S. Obukhova, Marina M. Ziganshina, Nadezhda V. Shilova, Alexander A. Chinarev, Galina V. Pazynina, Alexey Yu. Nokel, Anastasia V. Terenteva, Nailya R. Khasbiullina, Gennady T. Sukhikh, Aligeydar A. Ragimov, Emin L. Salimov, Veronika I. Butvilovskaya, Svetlana M. Polyakova, Jaideep Saha, Nicolai V. Bovin
Publikováno v:
Acta naturae. 14(2)
Previous studies have shown that in the blood of healthy donors (1) there are no natural antibodies against sialylated glycoproteins, which contain Neu5Ac (N-acetylneuraminic acid) as the most widespread form of human sialic acid, and (2) there is a
Autor:
Tatiana V. Tyrtysh, Inna S. Popova, Ivan M. Ryzhov, Svetlana V. Tsygankova, Nicolai V. Bovin, Galina V. Pazynina, Maria S. Savchenko
Publikováno v:
Mendeleev Communications. 29:680-682
The protected spacer-armed branched tri-N-acetyllactosamine has been synthesized as a building block for the synthesis of biantennary ABH blood group antigens. The key synthetic step is the simultaneous glycosylation of the 3′- and 6′-OH groups o
Publikováno v:
Carbohydrate research. 498
The traditionally used strategy for the synthesis of blood group A and B tetrasaccharides includes 2′-O-fucosylation of lactosamine followed by insertion of an α1-3 linked N-acetylgalactosamine or a galactose moiety. Here, we report the synthesis
Autor:
A S Gambaryan, A. B. Tuzikov, Alexander Chinarev, Amanda Balish, Galina V. Pazynina, N. V. Bovin, Alexander Klimov
Publikováno v:
Biochemistry. Biokhimiia. 84(10)
It was previously shown that hemagglutinin residues Thr155, Glu158, and Ser228 are crucial for the recognition of Neu5Gc. In this study, we demonstrated that the ability to bind the Neu5Gc-terminated receptor is related to the amino acid 145: viruses
Autor:
Galina V. Pazynina, Marina A. Sablina, Nadezhda Shilova, Alexander B. Tuzikov, Kira Dobrochaeva, Nicolai V. Bovin, Nailia Khasbiullina, Svetlana V. Tsygankova, Tatiana V. Ovchinnikova, Tatiana V. Tyrtysh
Publikováno v:
Carbohydrate Research. 445:23-31
Our understanding of biological role of glycans O-sulfation remains at the level of beginners due to microheterogeneity, lability and other difficulties of exact structural assignment. Partially, problem of functional investigations, especially deter
Autor:
Svetlana M. Polyakova, Svetlana V. Tsygankova, Andrey A. Formanovsky, Alexander S. Paramonov, Nicolai V. Bovin, Galina V. Pazynina, Nadezhda Shilova, Ivan M. Ryzhov
Publikováno v:
Mendeleev Communications. 29:254-255
We have synthesized GalNGcα1-3GalNAcα disaccharide, a glycoloyl analogue of GalNAcα1-3GalNAcα known as the core 5 motif of mucin-type glycoproteins, and investigated how this structural variation affects the interaction with human natural antibod
Publikováno v:
Russian Journal of Bioorganic Chemistry. 41:147-160
Oligosaccharides Galβ1-3GlcNAcβ-sp, GlcNAcβ1-3Galβ1-3GlcNAcβ-sp, Galβ1-3GlcNAcβ1-3Galβ1-3GlcNAcβ-sp, Galβ1-3GlcNAcβ1-3Galβ1-4GlcNAcβ-sp, Galβ1-3GlcNAcβ1-6Galβ1-4GlcNAcβ-sp (sp = O(CH2)3NH2 or O(CH2)2NH2) were synthesized using glycos