Zobrazeno 1 - 10
of 171
pro vyhledávání: '"Galina V Shurin"'
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0156095 (2016)
Nerve endings are often identified within solid tumors, but their impact on the tumor growth and progression remains poorly understood. Emerging data suggests that the central nervous system may affect cancer development and spreading via the hypotha
Externí odkaz:
https://doaj.org/article/daabf040b6104965874643854f9fcdac
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56886 (2013)
Paclitaxel (Pac) is an antitumor agent that is widely used for treatment of solid cancers. While being effective as a chemotherapeutic agent, Pac in high doses is neurotoxic, specifically targeting sensory innervations. In view of these toxic effects
Externí odkaz:
https://doaj.org/article/a359b9eee8934eb7b63ed93c687571f3
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
The lungs are a key organ in the respiratory system. They are regulated by a complex network of nerves that control their development, structure, function, and response to various pathological stimuli. Accumulating evidence suggests the involvement o
Externí odkaz:
https://doaj.org/article/a1b5f51fcad84366a5a983f847e64234
Autor:
Haider H. Dar, Michael W. Epperly, Vladimir A. Tyurin, Andrew A. Amoscato, Tamil S. Anthonymuthu, Austin B. Souryavong, Alexander A. Kapralov, Galina V. Shurin, Svetlana N. Samovich, Claudette M. St. Croix, Simon C. Watkins, Sally E. Wenzel, Rama K. Mallampalli, Joel S. Greenberger, Hülya Bayır, Valerian E. Kagan, Yulia Y. Tyurina
Publikováno v:
JCI Insight, Vol 7, Iss 4 (2022)
Total body irradiation (TBI) targets sensitive bone marrow hematopoietic cells and gut epithelial cells, causing their death and inducing a state of immunodeficiency combined with intestinal dysbiosis and nonproductive immune responses. We found enha
Externí odkaz:
https://doaj.org/article/064649aa63e64d92892a0366bc434be8
Publikováno v:
Cells, Vol 11, Iss 22, p 3541 (2022)
Nerve-cancer crosstalk resulting in either tumor neurogenesis or intratumoral neurodegeneration is critically controlled by Schwann cells, the principal glial cells of the peripheral nervous system. Though the direct stimulating effect of Schwann cel
Externí odkaz:
https://doaj.org/article/37bd44cded384cf5a8593c23967060c7
Autor:
Haider H. Dar, Tamil S. Anthonymuthu, Liubov A. Ponomareva, Austin B. Souryavong, Galina V. Shurin, Alexandr O. Kapralov, Vladimir A. Tyurin, Janet S. Lee, Rama K. Mallampalli, Sally E. Wenzel, Hülya Bayir, Valerian E. Kagan
Publikováno v:
Redox Biology, Vol 45, Iss , Pp 102045- (2021)
Ferroptosis is a redox-driven type of regulated cell death program arising from maladaptation of three metabolic pathways: glutathione homeostasis, iron handling and lipid peroxidation. Though GSH/Gpx4 is the predominant system detoxifying phospholip
Externí odkaz:
https://doaj.org/article/e3f67850337e451888b65ee03ea99b6a
Autor:
Sarah E. Wheeler, Galina V. Shurin, Mary Yost, Adam Anderson, Lisa Pinto, Alan Wells, Michael R. Shurin
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 1 (2021)
ABSTRACT Knowledge about development and duration of virus-specific antibodies after COVID-19 vaccination is important for understanding how to limit the pandemic via vaccination in different populations and societies. However, the clinical utility o
Externí odkaz:
https://doaj.org/article/410a73f3d2b14cb79a77bd22d7993833
Publikováno v:
Cells, Vol 10, Iss 2, p 454 (2021)
Surgery remains an essential therapeutic approach for most solid malignancies. Although for more than a century accumulating clinical and experimental data have indicated that surgical procedures themselves may promote the appearance and progression
Externí odkaz:
https://doaj.org/article/5844393fda0f481db49a6789c1fc31a5
Autor:
Yuri L. Bunimovich, Walter J. Storkus, Alex Zelikovsky, Michael R. Shurin, Pavel Skums, Uma R. Chandran, Galina V. Shurin, Jiying Zhang, Vishal Soman, Bikram Sahoo, Oleg Kruglov, Kavita Vats
Supplementary Figure from Sensory Nerves Impede the Formation of Tertiary Lymphoid Structures and Development of Protective Antimelanoma Immune Responses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9324cc7ec95d3b201f7810d3cc22ad58
https://doi.org/10.1158/2326-6066.22545318.v1
https://doi.org/10.1158/2326-6066.22545318.v1
Autor:
Yuri L. Bunimovich, Walter J. Storkus, Alex Zelikovsky, Michael R. Shurin, Pavel Skums, Uma R. Chandran, Galina V. Shurin, Jiying Zhang, Vishal Soman, Bikram Sahoo, Oleg Kruglov, Kavita Vats
Peripheral neurons comprise a critical component of the tumor microenvironment (TME). The role of the autonomic innervation in cancer has been firmly established. However, the effect of the afferent (sensory) neurons on tumor progression remains uncl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2406893375414ea7d6dba7affa659977
https://doi.org/10.1158/2326-6066.c.6550905.v1
https://doi.org/10.1158/2326-6066.c.6550905.v1