Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Galina T. Shishkina"'
Autor:
Galina T. Shishkina, Tatyana S. Kalinina, Dmitriy A. Lanshakov, Veta V. Bulygina, Natalya P. Komysheva, Anita V. Bannova, Ulyana S. Drozd, Nikolay N. Dygalo
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2595 (2023)
Inflammatory activation within the brain is linked to a decrease in cognitive abilities; however, the molecular mechanisms implicated in the development of inflammatory-related cognitive dysfunction and its prevention are poorly understood. This stud
Externí odkaz:
https://doaj.org/article/aeacb8b2871044d79783715d3c4cb4b4
Autor:
Vladimir N. Babenko, Galina T. Shishkina, Dmitriy A. Lanshakov, Ekaterina V. Sukhareva, Nikolay N. Dygalo
Publikováno v:
Biomolecules, Vol 12, Iss 2, p 277 (2022)
We performed transcriptome analysis in the hippocampus 24 h after lipopolysaccharide (LPS) administration. We observed glial-specific genes, comprised of two-thirds of all differentially expressed genes (DEGs). We found microglial DEGs that were the
Externí odkaz:
https://doaj.org/article/85fb7713ef0c4974a33bf526134e2d47
Autor:
Galina T. Shishkina, Natalia V. Gulyaeva, Dmitriy A. Lanshakov, Tatyana S. Kalinina, Mikhail V. Onufriev, Yulia V. Moiseeva, Ekaterina V. Sukhareva, Vladimir N. Babenko, Nikolay N. Dygalo
Publikováno v:
Biomedicines, Vol 9, Iss 12, p 1840 (2021)
Acute cerebral ischemia induces distant inflammation in the hippocampus; however, molecular mechanisms of this phenomenon remain obscure. Here, hippocampal gene expression profiles were compared in two experimental paradigms in rats: middle cerebral
Externí odkaz:
https://doaj.org/article/f03330572aee4a76aac577bea364a311
Autor:
Tatiana S Kalinina, Natalia V. Gulyaeva, D. A. Lanshakov, Galina T. Shishkina, Nikolay N. Dygalo
Publikováno v:
Biochemistry (Moscow). 86:657-666
Abstract Ischemic brain injuries are accompanied by the long-term changes in gene expression in the hippocampus, the limbic system structure, involved in the regulation of key aspects of the higher nervous activity, such as cognitive functions and em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db786088c0e721de7853b7493e458331
https://doi.org/10.1134/s0006297921060043
https://doi.org/10.1134/s0006297921060043
Publikováno v:
Neuroscience and Behavioral Physiology. 51:367-371
Susceptibility and resistance to depression is determined by the actions of the stimuli provoking it, including stressors and inflammatory processes, as well as the activity of the body’s protective systems, such as neurotrophins and antiapoptotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb53229fb32b41bbe6833c0c0f3dac6d
https://doi.org/10.1007/s11055-021-01080-8
https://doi.org/10.1007/s11055-021-01080-8
Publikováno v:
Stress. 23:700-707
Chronic stress can predispose vulnerable individuals to mood disorders, including depression. Glutamate, one of the key participants in this process, may exert both pathological and therapeutic psycho-emotional effects. However, the role of expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bfb3e0159f2c7b0ea505b47cea0e075
https://doi.org/10.1080/10253890.2020.1812574
https://doi.org/10.1080/10253890.2020.1812574
Publikováno v:
Stress. 23:708-714
Pathways by which inflammatory stimuli influence behaviors can involve changes in neuronal plasticity, however, the evidence for this is still insufficient. This study aimed to evaluate the effects of chronic lipopolysaccharide (LPS) injected alone o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f23e6e78acd6cad1d752a44b5d4e3728
https://doi.org/10.1080/10253890.2020.1793943
https://doi.org/10.1080/10253890.2020.1793943
Autor:
Galina T Shishkina, Tatyana S Kalinina, Veta V Bulygina, Dmitry A Lanshakov, Ekaterina V Babluk, Nikolay N Dygalo
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0143978 (2015)
Anti-apoptotic proteins are suggested to be important for the normal health of neurons and synapses as well as for resilience to stress. In order to determine whether stressful events may influence the expression of anti-apoptotic protein Bcl-xL in t
Externí odkaz:
https://doaj.org/article/91cc57ca06b042019139c613b7e37eca
Autor:
Galina T. Shishkina, E. V. Shaburova, Nikolay N. Dygalo, D. A. Lanshakov, E. V. Sukhareva, N. P. Komysheva, U. S. Drozd
Publikováno v:
Doklady Biochemistry and Biophysics. 490:16-18
Chemogenetic activation of glutamatergic neurons of the prefrontal cortex reduces the manifestations of psychoemotional anxiety during the juvenile period of ontogenesis. This result is the first evidence of feasibility of targeted chemogenetic contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd434e74df9726df3c0965cff9cd2f21
https://doi.org/10.1134/s1607672920010056
https://doi.org/10.1134/s1607672920010056
Autor:
Galina T. Shishkina, Nikolay N. Dygalo
Publikováno v:
Neuroscience and Behavioral Physiology. 49:178-183
Glutamatergic neurotransmission and the active brain neurotransmitter systems support the operation of mechanisms controlling psychoemotional status. Convincing evidence has now been reported on the involvement of brain areas key for regulating emoti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96b59792e062ba579c66d5a9a68799fa
https://doi.org/10.1007/s11055-019-00712-4
https://doi.org/10.1007/s11055-019-00712-4