Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Galina S. Monastyrskaya"'
Publikováno v:
Russian Journal of Genetics. 54:1416-1428
The review attempts to discuss the interaction of cancer cells and cells of the tumor microenvironment as well as the possibility of using them as a target for antitumor therapy.
Autor:
Raisa I. Yakubovskaya, Eugene D. Sverdlov, O. A. Bezborodova, A. R. Gevorkov, E. V. Khmelevskiy, J. B. Venediktova, A. V. Boyko, M. B. Kostina, E. R. Nemtsova, I. V. Alekseenko, Galina S. Monastyrskaya
Publikováno v:
Doklady Biochemistry and Biophysics. 470:345-348
Antitumor efficacy of the combined suicide gene therapy and radiotherapy was studied on the model of CT26 murine colon adenocarcinoma. CMV-FCU1-IRES-mGM-CSF-pGL3 construct with PEG-PEI-TAT (FCU1-mGM/5-FC) block copolymer as a vector was used for intr
Autor:
E. V. Snezhkov, Galina S. Monastyrskaya, Eugene D. Sverdlov, I. V. Alekseenko, A. I. Kuzmich, V. V. Pleshkan, D. A. Didych
Publikováno v:
Russian Journal of Genetics. 52:650-663
The review discusses the causes of multiple failures in cancer treatment, which might primarily result from the excessive variability of cancer genomes. They are capable of changing their spatial and temporal architecture during tumor development. Th
Publikováno v:
Molecular Genetics, Microbiology and Virology. 31:135-142
Embryonic development and carcinogenesis are controlled by many transcription factors, and regulatory systems involved in embryogenesis of an organ also participate in tumor development in the same organ. The FOX family proteins belong to transcripti
Autor:
Tatyana V. Vinogradova, Galina S. Monastyrskaya, E. D. Sverdlov, L. G. Kondratyeva, Igor P. Chernov
Publikováno v:
Acta Naturae. 7:46-55
Great successes in identification and deciphering of mechanisms of the adult stem cells regulation have given rise to the idea that stem cells can also function in tumors as central elements of their development, starting from the initial stage and c
Autor:
Eugene D. Sverdlov, Galina S. Monastyrskaya, Natalya Uspenskaya, E. P. Kopantzev, E. A. Stukacheva, Igor P. Chernov, K. N. Kashkin
Publikováno v:
Journal of Cellular Biochemistry. 116:299-309
Violation of proliferation control is a common feature of cancer cells. We put forward the hypothesis that promoters of genes involved in the control of cell proliferation should possess intrinsic cancer specific activity. We cloned promoter regions
Autor:
Eugene D. Sverdlov, A. V. Sass, Gennady T. Sukhikh, M. B. Kostina, M. V. Zinovyeva, O. B. Filyukova, Tatyana V. Vinogradova, N. Y. Uspenskaya, Galina S. Monastyrskaya, E. P. Kopantzev
Publikováno v:
Diseases of the Esophagus. 23:260-270
SUMMARY Here we directly compared gene expression profiles in human esophageal squamous cell carcinomas and in human fetal esophagus development. We used the suppression subtractive hybridization technique to subtract cDNAs prepared from tumor and no
Autor:
O. B. Filyukova, Alexander G. Tonevitsky, M. V. Zinovyeva, Marya B. Kostina, Tatyana V. Vinogradova, E.D. Sverdlov, E. P. Kopantzev, Gennady T. Sukhikh, Galina S. Monastyrskaya
Publikováno v:
Lung Cancer. 62:23-34
We, for the first time, directly compared gene expression profiles in human non-small cell lung carcinomas (NSCLCs) and in human fetal lung development. Previously reported correlations of gene expression profiles between lung cancer and lung develop
Autor:
Galina S. Monastyrskaya, E. P. Kopantzev, O. B. Filyukova, M. B. Kostina, Eugene D. Sverdlov, A. V. Sass, M. V. Zinovyeva, Tatyana V. Vinogradova
Publikováno v:
Doklady. Biochemistry and biophysics. 463
Publikováno v:
Research in Microbiology. 157:684-692
The ability to rapidly and efficiently identify causative agents of dangerous human and animal diseases is a prerequisite to diagnosis, prophylaxis and therapy. Such identification systems can be developed based on DNA markers enabling differentiatio