Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Galina R Demina"'
Autor:
Galina R Demina, Vadim A Makarov, Vadim D Nikitushkin, Olga B Ryabova, Galina N Vostroknutova, Elena G Salina, Margarita O Shleeva, Anna V Goncharenko, Arseny S Kaprelyants
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8174 (2009)
BACKGROUND: Resuscitation promoting factors (RPF) are secreted proteins involved in reactivation of dormant actinobacteria, including Mycobacterium tuberculosis. They have been considered as prospective targets for the development of new anti-tubercu
Externí odkaz:
https://doaj.org/article/b82fee09b81447d2990cced8ef951b67
Autor:
Galina R. Demina, Vadim D. Nikitushkin, Margarita O. Shleeva, Olga B. Riabova, Alexander Yu. Lepioshkin, Vadim A. Makarov, Arseny S. Kaprelyants
Publikováno v:
Annals of Clinical Microbiology and Antimicrobials, Vol 16, Iss 1, Pp 1-9 (2017)
Abstract Background Resuscitation promoting factors (Rpfs) are the proteins involved in the process of reactivation of the dormant cells of mycobacteria. Recently a new class of nitrophenylthiocyanates (NPTs), capable of inhibiting the biological and
Externí odkaz:
https://doaj.org/article/84dda092d5cd432a8567e843f99c0c14
Autor:
Galina R. Demina, M. O. Shleeva, Elena G. Salina, V. G. Avdienko, M. S. Shumkov, Arseny S. Kaprelyants, Kseniya A Trutneva
Publikováno v:
Applied Biochemistry and Microbiology. 57:170-179
Abstract The protein profile of dormant Mtb obtained after the gradual acidification of Mtb culture was studied to find antigenic proteins for humans that are expressed by M. tuberculosis (Mtb) cells in vitro under conditions close to the situation o
Autor:
Kseniya A Trutneva, G. N. Vostroknutova, Galina R. Demina, Arseny S Kaprelyans, M. O. Shleeva
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
For adaptation to stressful conditions, Mycobacterium tuberculosis (Mtb) is prone to transit to a dormant, non-replicative state, which is believed to be the basis of the latent form of tuberculosis infection. Dormant bacteria persist in the host for
Autor:
M. O. Shleeva, Alexander Lepioshkin, Olga Riabova, Arseny S. Kaprelyants, Galina R. Demina, Vadim Makarov, Vadim D. Nikitushkin
Publikováno v:
Annals of Clinical Microbiology and Antimicrobials, Vol 16, Iss 1, Pp 1-9 (2017)
Annals of Clinical Microbiology and Antimicrobials
Annals of Clinical Microbiology and Antimicrobials
Background Resuscitation promoting factors (Rpfs) are the proteins involved in the process of reactivation of the dormant cells of mycobacteria. Recently a new class of nitrophenylthiocyanates (NPTs), capable of inhibiting the biological and enzymati
Autor:
Vadim D. Nikitushkin, Arseny S. Kaprelyants, Galina R. Demina, Sandra Trenkamp, M. O. Shleeva
Publikováno v:
Metabolomics : Official journal of the Metabolomic Society. 16(2)
Under gradual acidification of the culture medium mycobacterial cells transit into a specific state characterized by low level of metabolic activity and morphological alterations. This state of non-replicative persistence (dormancy) is directly linke
Autor:
Kseniya A, Trutneva, Margarita O, Shleeva, Galina R, Demina, Galina N, Vostroknutova, Arseny S, Kaprelyans
Publikováno v:
Frontiers in Cellular and Infection Microbiology
For adaptation to stressful conditions, Mycobacterium tuberculosis (Mtb) is prone to transit to a dormant, non-replicative state, which is believed to be the basis of the latent form of tuberculosis infection. Dormant bacteria persist in the host for
Autor:
Arseny S. Kaprelyants, Vadim D. Nikitushkin, Galina R. Demina, Kseniya A Trutneva, M. O. Shleeva
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Mycobacteria are able to form dormant cells, which survive for a long time without multiplication. The molecular mechanisms behind prolonged survival of dormant cells are not fully described. In particular, little information is known on biochemical
Autor:
Margarita O. Shleeva, Tatyana K. Kondratieva, Galina R. Demina, Elvira I. Rubakova, Anna V. Goncharenko, Alexander S. Apt, Arseny S. Kaprelyants
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
Earlier we demonstrated that the adenylyl cyclase (AC) encoded by the MSMEG_4279 gene plays a key role in the resuscitation and growth of dormant Mycobacterium smegmatis and that overexpression of this gene leads to an increase in intracellular cAMP
Autor:
Galina M Sorokoumova, Margarita O. Shleeva, Arseny S. Kaprelyants, Alexander I. Zinin, E. S. Shumkova, Polina K. Laptinskaya, Galina R. Demina, Kseniya A Trutneva
Publikováno v:
Frontiers in Microbiology. 8
Under gradual acidification of growth medium resulting in the formation of dormant Mycobacterium smegmatis, a significant accumulation of free trehalose in dormant cells was observed. According to 1H- and 13C-NMR spectroscopy up to 64% of total organ