Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Galina Pogosov"'
Autor:
Frederick R. Appelbaum, Jerald P. Radich, John E. Godwin, Era L. Pogosova-Agadjanyan, Min Fang, I-Ming L. Chen, Derek L. Stirewalt, Cheryl L. Willman, Alan F. List, Kenneth J. Kopecky, Harry P. Erba, Thomas R. Chauncey, Brent L. Wood, Megan Othus, Anna Moseley, Galina Pogosov, Soheil Meshinchi
Publikováno v:
Biopreservation and Biobanking. 16:42-52
Current prognostic models for acute myeloid leukemia (AML) are inconsistent at predicting clinical outcomes for individual patients. Variability in the quality of specimens utilized for biomarker discovery and validation may contribute to this progno
Autor:
Frederick R. Appelbaum, Derek L. Stirewalt, Fabiana Ostronoff, Alan F. List, Jennifer J. May, Cheryl L. Willman, Soheil Meshinchi, John Godwin, Kenneth J. Kopecky, Galina Pogosov, Vivian G. Oehler, Steve Petersdorf, Hana Lee, Era L. Pogosova-Agadjanyan, Jerald P. Radich
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 8, p e70812 (2013)
PLoS ONE, Vol 8, Iss 8, p e70812 (2013)
Interferon regulatory factor 8 (IRF8) is a transcription factor that plays a critical role in normal hematopoiesis, such that disruption of IRF8 activity promotes leukemogenesis. We and others have identified aberrant expression of IRF8 transcripts,
Autor:
Ilana M. Roberts, Galina Pogosov, Jeff Pufnock, William Y. Ho, Colette Chaney, Hieu Nguyen, Natalie Duerkopp, Gunnar B. Ragnarsson, Philip D. Greenberg, Cassian Yee, Aude G. Chapuis, Jerald P. Radich, Merav Bar, Tomas Schmitt
Publikováno v:
Blood. 120:350-350
Abstract 350 Relapse is the leading cause of death following allogeneic hematopoietic cell transplant (HCT) for hematological malignancies. Although evidence suggests that the beneficial donor T cell-mediated graft versus leukemia (GVL) effect can re
Autor:
Bruce E. Clurman, Sue E. Knoblaugh, Yongiae E. Choi, Galina Pogosov, Keith R. Loeb, Brian M. Fissel, Brent L. Wood, Bridget T. Hughes
Publikováno v:
Blood. 120:2407-2407
Abstract 2407 Background and Methods: Cyclin E-Cdk2 is a cell cycle regulator that promotes the G1-S transition by phosphorylating proteins involved in cell division and genome duplication. Cyclin E activity is frequently increased in many cancers, u
Autor:
Olga Sala Torra, Galina Pogosov, Jerald P. Radich, Holly Gundacker, Cheryl L. Willman, Era L. Pogosova-Agadjanyan, Frederick R. Appelbaum, Stephen J. Forman, Margaret R. O'Donnell
Publikováno v:
Blood. 116:758-758
Abstract 758 Adult acute lymphoblastic leukemia (ALL) is a heterogeneous disease with low overall survival. Compared to pediatric ALL, outcomes for adults have not improved despite recent advances in therapy and treatment support. Novel targets and b
Autor:
Brian Lannutti, Adam Kashishian, Jerald P. Radich, Bart H. Steiner, Amy J. Johnson, Olga Sala-Torra, Neill A. Giese, Sarah A. Meadows, Galina Pogosov, John C. Byrd
Publikováno v:
Blood. 114:286-286
Abstract 286 It is well established that deregulation of the PI3K signaling pathway plays an important role in the etiology of human malignancies including those of hematologic origin. In 30–50% of solid tumors, oncogenic activation of the PI3K pat