Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Galina POLEKHINA"'
Autor:
Moeen Riaz, Jonas Mattisson, Galina Polekhina, Andrew Bakshi, Jonatan Halvardson, Marcus Danielsson, Adam Ameur, John McNeil, Lars A. Forsberg, Paul Lacaze
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Background Mosaic loss of Y chromosome (LOY) is the most common somatic change that occurs in circulating white blood cells of older men. LOY in leukocytes is associated with increased risk for all-cause mortality and a range of common disea
Externí odkaz:
https://doaj.org/article/6c13a30b4ab04fb99c76deb137dfceec
Autor:
Andrew Tonkin, John J McNeil, Sophia Zoungas, Galina Polekhina, Chris Reid, Eric Schadt, Jing Pang, Paul Lacaze, Stephen Nicholls, Jane Tiller, Robert Sebra, Moeen Riaz, Amanda J Hooper, Anne M Murray, Gerald Watts
Publikováno v:
Open Heart, Vol 8, Iss 2 (2021)
Objective Genetic variants that disrupt the function of the PCSK9 (proprotein convertase subtilisin kexin type 9) and APOB (apolipoprotein B)genes result in lower serum low-density lipoprotein cholesterol (LDL-C) levels and subsequently confer protec
Externí odkaz:
https://doaj.org/article/f2a0c21ae33945799dc776cad9983f03
Autor:
Paul Lacaze, Yuanyuan Wang, Galina Polekhina, Andrew Bakshi, Moeen Riaz, Alice Owen, Angus Franks, Jawad Abidi, Jane Tiller, John McNeil, Flavia Cicuttini
Publikováno v:
Arthritis & Rheumatology. 74:1480-1487
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::465d7fe34ac653b552e86c7c43b11eee
https://doi.org/10.1002/art.42156
https://doi.org/10.1002/art.42156
Autor:
Mark R. Nelson, Galina Polekhina, Robyn L. Woods, Christopher M. Reid, Andrew M. Tonkin, Rory Wolfe, Anne M. Murray, Brenda Kirpach, Michael E. Ernst, Jessica E. Lockery, Raj C. Shah, Nigel Stocks, Suzanne G. Orchard, Zhen Zhou
Publikováno v:
Annals of Internal Medicine. 175:761-764
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8d79e84bc05fc99c5a39a3d7d9404bb
https://doi.org/10.7326/m21-3823
https://doi.org/10.7326/m21-3823
Autor:
Johannes T Neumann, Le T P Thao, Emily Callander, Prudence R Carr, Vazhma Qaderi, Mark R Nelson, Christopher M Reid, Robyn L Woods, Suzanne G Orchard, Rory Wolfe, Galina Polekhina, Jeff D Williamson, James M Trauer, Anne B Newman, Anne M Murray, Michael E Ernst, Andrew M Tonkin, John J McNeil
Publikováno v:
Lancet Healthy Longev
BACKGROUND: Understanding the nature of transitions from a healthy state to chronic diseases and death is important for planning health-care system requirements and interventions. We aimed to quantify the trajectories of disease and disability in a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a05b6f3bddeb24368a5eeefc76212779
https://doi.org/10.1016/s2666-7568(21)00308-1
https://doi.org/10.1016/s2666-7568(21)00308-1
Autor:
Maciej Tatarczuch, Mark Waltham, Jake Shortt, Galina Polekhina, Eliza A Hawkes, Shir-Jing Ho, Judith Trotman, Daniella Brasacchio, Melannie Co, Jessica Li, Vanitha Ramakrishnan, Karin Dunne, Stephen S. Opat, Gareth P. Gregory
Publikováno v:
Blood Advances.
Utilising tissue whole exome sequencing (WES) and circulating tumor cell-free DNA (ctDNA), this Australasian Leukaemia & Lymphoma Group (ALLG) translational study sought to characterise primary and acquired molecular determinants of response and resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34749dc35985ef09fbc8f3ce50e21131
https://doi.org/10.1182/bloodadvances.2022009412
https://doi.org/10.1182/bloodadvances.2022009412
Publikováno v:
JNCI Cancer Spectrum. 7
Background Metformin and aspirin are commonly co-prescribed to people with diabetes. Metformin may prevent cancer, but in older people (over 70 years), aspirin has been found to increase cancer mortality. This study examined whether metformin reduces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c6c7b6854244651cf31939bd89af792
https://doi.org/10.1093/jncics/pkad017
https://doi.org/10.1093/jncics/pkad017
Autor:
Swarna Vishwanath, Ingrid Hopper, Rory Wolfe, Galina Polekhina, Christopher M. Reid, Andrew M. Tonkin, Anne M. Murray, Raj C. Shah, Elsdon Storey, Robyn L. Woods, John McNeil, Suzanne G. Orchard, Mark R. Nelson, Claire J. Steves, Joanne Ryan
Publikováno v:
Alzheimer's & Dementia.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::797784217c99d24bb95cea19f664a120
https://doi.org/10.1002/alz.13006
https://doi.org/10.1002/alz.13006
Autor:
John J McNeil, Le T P Thao, Paul Lacaze, Andrew Bakshi, Mark Nelson, Geoffrey A Donnan, Gad Abraham, Jeff D. Williamson, Galina Polekhina, Michael Inouye, Andrew M. Tonkin, Robyn L. Woods, Christopher M. Reid, Johannes T Neumann, Amy Brodtmann, Geoffrey Cloud, Moeen Riaz
Publikováno v:
Stroke
Background and Purpose: Polygenic risk scores (PRSs) can be used to predict ischemic stroke (IS). However, further validation of PRS performance is required in independent populations, particularly older adults in whom the majority of strokes occur.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09bedba652286b04bca9235e48821eb0
https://doi.org/10.1161/strokeaha.120.033670
https://doi.org/10.1161/strokeaha.120.033670
Autor:
Mark Nelson, Christopher M. Reid, Sophia Xie, Joshua P. Lewis, Alan R. Shuldiner, Andrew Tonkin, Paul Lacaze, Rory Wolfe, John J McNeil, Galina Polekhina, Anne M. Murray, Moeen Riaz
Publikováno v:
Clin Pharmacol Ther
The platelet endothelial aggregation receptor-1 (PEAR1) rs12041331 variant has been identified as a genetic determinant of platelet aggregation in response to antiplatelet therapies, including aspirin. However, association with atherothrombotic cardi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dec79de76bdd0918a3ca4350cf1c6a17
https://doi.org/10.1002/cpt.1959
https://doi.org/10.1002/cpt.1959