Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Galina Meier"'
Autor:
C. Robin Ganellin, Heinz H. Pertz, Michael Krause, Holger Stark, Schwartz Jc, A Huls, X Ligneau, Jean-Michel Batiment Arrang, W Schunack, Galina Meier
Publikováno v:
Journal of Medicinal Chemistry. 47:2678-2687
In an effort to develop new histamine H(3) receptor antagonists usable as pharmacological tools we present here novel unsymmetrical ether derivatives. Etherification of different omega-(1H-imidazol-4-yl)alkyl scaffolds led to compounds containing alk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::743fba750a413ecf8328fe8244e11b39
https://doi.org/10.1021/jm031065q
https://doi.org/10.1021/jm031065q
Autor:
Susanna Liedtke, Galina Meier, Holger Stark, M. Kathmann, Eberhard Schlicker, Walter Schunack, K Flau
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 367:43-50
We examined whether replacement of imidazole by a piperidine or pyrrolidine moiety will affect the potency and affinity of six H3-receptor antagonists. Potencies were determined in superfused mouse brain cortex slices preincubated with [3H]noradrenal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0309db86de0895b9fa6d81875541a554
https://doi.org/10.1007/s00210-002-0649-4
https://doi.org/10.1007/s00210-002-0649-4
Autor:
Walter Schunack, C. Robin Ganellin, Xavier Ligneau, Holger Stark, Jean-Charles Schwartz, Fabien Leurquin, Galina Meier, Joachim Apelt, Sven Graßmann, Ulrich Reichert, Sigurd Elz
Publikováno v:
European Journal of Pharmaceutical Sciences. 13:249-259
The reference compounds for histamine H(3)-receptor antagonists carry as a common feature an imidazole moiety substituted in the 4-position. Very recently novel ligands lacking an imidazole ring have been described possessing a N-containing non-aroma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::087ebf1543e7aa762dd292036962f13f
https://doi.org/10.1016/s0928-0987(01)00106-3
https://doi.org/10.1016/s0928-0987(01)00106-3
Autor:
Jean-Charles Schwartz, Walter Schunack, C. Robin Ganellin, Galina Meier, Heinz H. Pertz, Holger Stark, Xavier Ligneau
Publikováno v:
Bioorganicmedicinal chemistry. 10(8)
In search for novel non-imidazole histamine H 3 -receptor antagonists, piperidino-hydrocarbon compounds were synthesized using the known non-imidazole histamine H 3 -receptor antagonist FUB 637 (3-phenylpropyl 3-piperidinopropyl ether) as lead struct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6585af1f2516960d41efba9acdbf78fc
https://pubmed.ncbi.nlm.nih.gov/12057642
https://pubmed.ncbi.nlm.nih.gov/12057642