Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Galina L. Mukhina"'
Autor:
Jeffrey J. Pu, Rong Hu, Galina L. Mukhina, Hetty E. Carraway, Michael A. McDevitt, Robert A. Brodsky
Publikováno v:
Haematologica, Vol 97, Iss 8 (2012)
Background Patients with paroxysmal nocturnal hemoglobinuria harbor clonal glycosylphosphatidylinositol-anchor deficient cells arising from a multipotent hematopoietic stem cell acquiring a PIG-A mutation. Many patients with aplastic anemia and myelo
Externí odkaz:
https://doaj.org/article/d999285ebc1d4caab8056270a40b0ec5
Publikováno v:
European Journal of Haematology. 87:37-45
Objective Investigate the natural history of PNH clones in patients with acquired aplastic anemia (AA).
Autor:
Rong Hu, Richard J. Jones, Jamie P. Barber, Robert A. Brodsky, Steven Piantadosi, Galina L. Mukhina
Publikováno v:
Blood. 105:3848-3854
Paroxysmal nocturnal hemoglobinuria (PNH) is caused by phosphatidylinositol glycan–class A (PIG-A) mutations in hematopoietic stem cells (HSCs). PIG-A mutations have been found in granulocytes from most healthy individuals, suggesting that these sp
Publikováno v:
British Journal of Haematology. 115:476-482
Aplastic anaemia and paroxysmal nocturnal haemoglobinuria (PNH) are closely related disorders. In PNH, haematopoietic stem cells that harbour PIGA mutations give rise to blood elements that are unable to synthesize glycosylphosphatidylinositol (GPI)
Autor:
Robert A. Brodsky, Galina L. Mukhina, Kim L. Nelson, Tracy S. Lawrence, Richard J. Jones, J. Thomas Buckley
Publikováno v:
Blood. 93:1749-1756
Paroxysmal nocturnal hemoglobinuria (PNH) is a clonal stem cell disorder caused by a somatic mutation of the PIGA gene. The product of this gene is required for the biosynthesis of glycosylphosphatidylinositol (GPI) anchors; therefore, the phenotypic
Autor:
Xuan Yuan, Amy E. DeZern, Jeffrey J. Pu, Marc E. Uknis, Robert A. Brodsky, Galina L. Mukhina, Juan Carlos Varela, Jo Anne Saye
Publikováno v:
Experimental hematology. 42(10)
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, clonal, hematopoietic stem cell disorder that manifests with a complement-mediated hemolytic anemia, bone marrow failure and a propensity for thrombosis. These patients experience both intra- and e
Autor:
Nadine Budd, Lauren Butler, Joel Gittelsohn, Fariba Kolahdooz, Galina L. Mukhina, Benjamin Caballero, Sangita Sharma, Berenice Rushovich
Publikováno v:
Nutrition Journal
Objective To characterize food and nutrient intake and develop a population-specific food list to be used as a comprehensive dietary assessment tool for Baltimore infants and toddlers aged 0–24 months. The data were used to inform the Growing Leaps
Publikováno v:
Acta Haematologica. 107:182-184
Publikováno v:
British journal of haematology. 126(1)
Paroxysmal nocturnal haemoglobinuria (PNH) is an uncommon, acquired disorder of blood cells caused by mutation of the phosphatidylinositol glycan class A (PIG-A) gene. The disease often manifests with haemoglobinuria, peripheral blood cytopenias, and
Publikováno v:
Leukemialymphoma. 45(4)
Rituximab, an anti-CD20 monoclonal antibody used to treat B cell lymphoproliferative disorders and autoimmune diseases, kills cells through complement dependent cytotoxicity, antibody-dependent cellular toxicity and apoptosis. A mechanism of resistan