Zobrazeno 1 - 10
of 188
pro vyhledávání: '"Galina K. Sukhova"'
Autor:
Yuanyuan Zhang, Tianxiao Liu, Zhiyong Deng, Wenqian Fang, Xian Zhang, Shuya Zhang, Minjie Wang, Songyuan Luo, Zhaojie Meng, Jing Liu, Galina K. Sukhova, Dazhu Li, Andrew N. J. McKenzie, Peter Libby, Guo‐Ping Shi, Junli Guo
Publikováno v:
Advanced Science, Vol 10, Iss 7, Pp n/a-n/a (2023)
Abstract Development of abdominal aortic aneurysms (AAA) enhances lesion group‐2 innate lymphoid cell (ILC2) accumulation and blood IL5. ILC2 deficiency in Rorafl/flIl7rCre/+ mice or induced ILC2 depletion in Icosfl‐DTR‐fl/+Cd4Cre/+ mice expedi
Externí odkaz:
https://doaj.org/article/5088f16849cc46d4b5b3ce3f82354472
Autor:
Jing Liu, Chongzhe Yang, Tianxiao Liu, Zhiyong Deng, Wenqian Fang, Xian Zhang, Jie Li, Qin Huang, Conglin Liu, Yunzhe Wang, Dafeng Yang, Galina K. Sukhova, Jes S. Lindholt, Axel Diederichsen, Lars M. Rasmussen, Dazhu Li, Gail Newton, Francis W. Luscinskas, Lijun Liu, Peter Libby, Jing Wang, Junli Guo, Guo-Ping Shi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Blood eosinophil (EOS) counts may serve as risk factors for human coronary heart diseases. Here the authors show that increased circulating and myocardial EOS after myocardial infarction play a cardioprotective role by reducing cardiomyocyte death, c
Externí odkaz:
https://doaj.org/article/55842ce25e9141999c860602412da2fc
Autor:
Cong-Lin Liu, Xian Zhang, Jing Liu, Yunzhe Wang, Galina K. Sukhova, Gregory R. Wojtkiewicz, Tianxiao Liu, Rui Tang, Samuel Achilefu, Matthias Nahrendorf, Peter Libby, Junli Guo, Jin-Ying Zhang, Guo-Ping Shi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Na+-H+ exchanger 1 (Nhe1) regulates extracellular pH by extruding protons in exchange for extracellular Na+ . Here, Liu et al. show that Nhe1 promotes the development and acidification of atherosclerotic lesions and that pH-sensitive probes can be us
Externí odkaz:
https://doaj.org/article/b0bd30f23bbe46f4ac1f69c4a193d1c1
Autor:
Xian Zhang, Yi Zhou, Xueqing Yu, Qin Huang, Wenqian Fang, Jie Li, Joseph V. Bonventre, Galina K. Sukhova, Peter Libby, Guo-Ping Shi
Publikováno v:
iScience, Vol 19, Iss , Pp 607-622 (2019)
Summary: Transforming growth factor beta (TGF-β) signaling contributes to tissue fibrosis. Here we demonstrate that TGF-β enhances CatS and CatK expression but reduces CatB and CatL expression in mouse kidney tubular epithelial cells (TECs). CatS-
Externí odkaz:
https://doaj.org/article/c5d7092c6628449f8cdaef3da8ff9943
Autor:
Cong-Lin Liu, Marcela M. Santos, Cleverson Fernandes, Mengyang Liao, Karine Iamarene, Jin-Ying Zhang, Galina K. Sukhova, Guo-Ping Shi
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Toll-like receptor 7 (TLR7) mediates autoantigen and viral RNA-induced cytokine production. Increased TLR7 expression in human atherosclerotic lesions suggests its involvement in atherogenesis. Here we demonstrated TLR7 expression in macroph
Externí odkaz:
https://doaj.org/article/0745c230f414429ab9e7bee09e14902b
Autor:
Eva H.C. Tang, Yin Cai, Chi Kin Wong, Viviane Z. Rocha, Galina K. Sukhova, Koichi Shimizu, Ge Xuan, Paul M. Vanhoutte, Peter Libby, Aimin Xu
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 2, Pp 358-368 (2015)
Inflammation of adipose tissue induces metabolic derangements associated with obesity. Thus, determining ways to control or inhibit inflammation in adipose tissue is of clinical interest. The present study tested the hypothesis that in mouse adipose
Externí odkaz:
https://doaj.org/article/6b1c2f280ab74f8896a51818149a0bbb
Autor:
Chongzhe Yang, Jie Li, Zhiyong Deng, Songyuan Luo, Jing Liu, Wenqian Fang, Feng Liu, Tianxiao Liu, Xian Zhang, Yuanyuan Zhang, Zhaojie Meng, Shuya Zhang, Jianfang Luo, Conglin Liu, Dafeng Yang, Lijun Liu, Galina K Sukhova, Anastasiia Sadybekov, Vsevolod Katritch, Peter Libby, Jing Wang, Junli Guo, Guo-Ping Shi
Publikováno v:
Cardiovascular Research. 119:195-212
Aims Blood eosinophil (EOS) counts and EOS cationic protein (ECP) levels associate positively with major cardiovascular disease (CVD) risk factors and prevalence. This study investigates the role of EOS in cardiac hypertrophy. Methods and results A r
Autor:
Livia S A, Passos, Prabhash K, Jha, Dakota, Becker-Greene, Mark C, Blaser, Dayanna, Romero, Adrien, Lupieri, Galina K, Sukhova, Peter, Libby, Sasha A, Singh, Walderez O, Dutra, Masanori, Aikawa, Robert A, Levine, Maria C P, Nunes, Elena, Aikawa
Publikováno v:
Circulation
BACKGROUND: Rheumatic heart valve disease (RHVD) is a leading cause of cardiovascular death in low-middle-income countries and affects predominantly women. However, the underlying mechanisms of valvular damage remain scant, and regulators of sex pred
Autor:
Livia S.A. Passos, Prabhash K. Jha, Dakota Becker-Greene, Mark C. Blaser, Dayanna Romero, Adrien Lupieri, Galina K. Sukhova, Peter Libby, Sasha A. Singh, Walderez O. Dutra, Masanori Aikawa, Robert A. Levine, Maria C.P. Nunes, Elena Aikawa
Publikováno v:
Circulation. 145:531-548
Background: Rheumatic heart valve disease (RHVD) is a leading cause of cardiovascular death in low- and middle-income countries and affects predominantly women. The underlying mechanisms of chronic valvular damage remain unexplored and regulators of
Autor:
Daniel Pérez-Cremades, A.K.M. Khyrul Wara, Stefan Haemmig, Yihuan Deng, Qiuyan Dai, Eugenia Shvartz, Viorel Simion, Galina K. Sukhova, Dafeng Yang, Huaner Ni, Carmel Assa, Rulin Zhuang, Mark W. Feinberg, Jingshu Chen, Grasiele Sausen, Henry S. Cheng
Publikováno v:
Arterioscler Thromb Vasc Biol
Objective: Vascular smooth muscle cell (VSMC) plasticity plays a critical role in the development of atherosclerosis. Long noncoding RNAs (lncRNAs) are emerging as important regulators in the vessel wall and impact cellular function through diverse i