Zobrazeno 1 - 10
of 188
pro vyhledávání: '"Galina K Sukhova"'
Autor:
Jing Wang, Jes S Lindholt, Galina K Sukhova, Michael A Shi, Mingcan Xia, Han Chen, Meixiang Xiang, Aina He, Yi Wang, Na Xiong, Peter Libby, Jian‐An Wang, Guo‐Ping Shi
Publikováno v:
EMBO Molecular Medicine, Vol 6, Iss 7, Pp 952-969 (2014)
Abstract Immunoglobulin E (IgE) activates mast cells (MCs). It remains unknown whether IgE also activates other inflammatory cells, and contributes to the pathogenesis of abdominal aortic aneurysms (AAAs). This study demonstrates that CD4+ T cells ex
Externí odkaz:
https://doaj.org/article/42c6f3509a484046914cdb7a4ae8d78b
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152474 (2016)
AIMS:Mice deficient in IL-1 receptor 1 (hence unresponsive to both IL-1 isoforms α and β) have impaired expansive arterial remodeling due to diminished expression of matrix-degrading enzymes, especially MMP-3. Emergence of IL-1 as a target in cardi
Externí odkaz:
https://doaj.org/article/e2d7863b27094ec39d06e593ec76e15c
Autor:
Weifang Yu, Jian Liu, Michael A Shi, Jianan Wang, Meixiang Xiang, Shiro Kitamoto, Bing Wang, Galina K Sukhova, George F Murphy, Gabriela Orasanu, Anders Grubb, Guo-Ping Shi
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e13973 (2010)
Cysteine protease cathepsins are important in extracellular matrix protein degradation, cell apoptosis, and angiogenesis. Mice lacking cathepsins are protected from tumor progression in several animal models, suggesting that the regulation of catheps
Externí odkaz:
https://doaj.org/article/ec9314e32aaf42bab27d51b2715e776c
Autor:
Chongzhe Yang, Jie Li, Zhiyong Deng, Songyuan Luo, Jing Liu, Wenqian Fang, Feng Liu, Tianxiao Liu, Xian Zhang, Yuanyuan Zhang, Zhaojie Meng, Shuya Zhang, Jianfang Luo, Conglin Liu, Dafeng Yang, Lijun Liu, Galina K Sukhova, Anastasiia Sadybekov, Vsevolod Katritch, Peter Libby, Jing Wang, Junli Guo, Guo-Ping Shi
Publikováno v:
Cardiovascular Research. 119:195-212
Aims Blood eosinophil (EOS) counts and EOS cationic protein (ECP) levels associate positively with major cardiovascular disease (CVD) risk factors and prevalence. This study investigates the role of EOS in cardiac hypertrophy. Methods and results A r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0db6445ff90a01f0df72d8d09820a6b2
https://doi.org/10.1093/cvr/cvac060
https://doi.org/10.1093/cvr/cvac060
Autor:
Livia S.A. Passos, Prabhash K. Jha, Dakota Becker-Greene, Mark C. Blaser, Dayanna Romero, Adrien Lupieri, Galina K. Sukhova, Peter Libby, Sasha A. Singh, Walderez O. Dutra, Masanori Aikawa, Robert A. Levine, Maria C.P. Nunes, Elena Aikawa
Publikováno v:
Circulation. 145:531-548
Background: Rheumatic heart valve disease (RHVD) is a leading cause of cardiovascular death in low- and middle-income countries and affects predominantly women. The underlying mechanisms of chronic valvular damage remain unexplored and regulators of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d02cb975764504dc5361d8c4a1a81ab0
https://doi.org/10.1161/circulationaha.121.057301
https://doi.org/10.1161/circulationaha.121.057301
Autor:
Livia S A, Passos, Prabhash K, Jha, Dakota, Becker-Greene, Mark C, Blaser, Dayanna, Romero, Adrien, Lupieri, Galina K, Sukhova, Peter, Libby, Sasha A, Singh, Walderez O, Dutra, Masanori, Aikawa, Robert A, Levine, Maria C P, Nunes, Elena, Aikawa
Publikováno v:
Circulation
BACKGROUND: Rheumatic heart valve disease (RHVD) is a leading cause of cardiovascular death in low-middle-income countries and affects predominantly women. However, the underlying mechanisms of valvular damage remain scant, and regulators of sex pred
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cb35f9e56c916f4a6bb79c289c7b7b98
https://pubmed.ncbi.nlm.nih.gov/35157519
https://pubmed.ncbi.nlm.nih.gov/35157519
Autor:
Daniel Pérez-Cremades, A.K.M. Khyrul Wara, Stefan Haemmig, Yihuan Deng, Qiuyan Dai, Eugenia Shvartz, Viorel Simion, Galina K. Sukhova, Dafeng Yang, Huaner Ni, Carmel Assa, Rulin Zhuang, Mark W. Feinberg, Jingshu Chen, Grasiele Sausen, Henry S. Cheng
Publikováno v:
Arterioscler Thromb Vasc Biol
Objective: Vascular smooth muscle cell (VSMC) plasticity plays a critical role in the development of atherosclerosis. Long noncoding RNAs (lncRNAs) are emerging as important regulators in the vessel wall and impact cellular function through diverse i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae0ea45b33af8772faed1bafb94148ed
https://doi.org/10.1161/atvbaha.120.315911
https://doi.org/10.1161/atvbaha.120.315911
Autor:
Antonios P. Antoniadis, Peter Libby, Elazer R. Edelman, Ali Hashemi Gheinani, Mark W. Feinberg, Fred G.P. Welt, Stefan Haemmig, Ahmet U. Coskun, Peter Stone, David A. Gross, A.K.M. Khyrul Wara, Li-Ming Gan, Michelle A. Cormier, Galina K. Sukhova, Johannes Wikström, Carl Whatling, Ioannis Andreou, Marina Zaromytidou, Xinghui Sun, Gerasimos Siasos
Publikováno v:
Arterioscler Thromb Vasc Biol
Objective: Accelerated atherosclerosis in diabetes constitutes an ongoing challenge despite optimal medical therapies. This study aimed to identify evolutionarily conserved lesion-based regulatory signaling networks in diabetic versus nondiabetic con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e921bfe94e44285f2c16a5b7cc1fd0ed
https://doi.org/10.1161/atvbaha.121.315896
https://doi.org/10.1161/atvbaha.121.315896
Autor:
Tianxiao Liu, Peter Libby, Xin Liu, Gregory R. Wojtkiewicz, Matthias Nahrendorf, Yunzhe Wang, Samuel Achilefu, Xiao-Fang Wang, Cong-Lin Liu, Jin Ying Zhang, Zhiyong Deng, Guo-Ping Shi, Galina K. Sukhova, Rui Tang
Publikováno v:
Hypertension. 76:87-100
IgE-mediated activation of Nhe1 (Na + -H + exchanger-1) induces aortic cell extracellular acidification and promotes cell apoptosis. A pH-sensitive probe pHrodo identified acidic regions at positions of macrophage accumulation, IgE expression, and ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b19b13f2eb16f38358cc94f7d307d21a
https://doi.org/10.1161/hypertensionaha.119.14485
https://doi.org/10.1161/hypertensionaha.119.14485
Autor:
Yuanyuan Zhang, Tianxiao Liu, Zhiyong Deng, Wenqian Fang, Xian Zhang, Shuya Zhang, Minjie Wang, Songyuan Luo, Zhaojie Meng, Jing Liu, Galina K. Sukhova, Dazhu Li, Andrew N. J. McKenzie, Peter Libby, Guo‐Ping Shi, Junli Guo
Publikováno v:
Advanced Science. 10:2206958
Development of abdominal aortic aneurysms (AAA) enhances lesion group-2 innate lymphoid cell (ILC2) accumulation and blood IL5. ILC2 deficiency in Rora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3d5289f6d9e0627cf69f011b00ac91d
https://doi.org/10.1002/advs.202206958
https://doi.org/10.1002/advs.202206958