Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Galina Hovhannisyan"'
Autor:
Tigran Harutyunyan, Anzhela Sargsyan, Lily Kalashyan, Naira Stepanyan, Rouben Aroutiounian, Thomas Liehr, Galina Hovhannisyan
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10293 (2024)
The ability of the SARS-CoV-2 virus to cause DNA damage in infected humans requires its study as a potential indicator of COVID-19 progression. DNA damage was studied in leukocytes of 65 COVID-19 patients stratified by sex, age, and disease severity
Externí odkaz:
https://doaj.org/article/d99b4953cd6848e0ba104bd0b82e42fe
Changes in Telomere Length in Leukocytes and Leukemic Cells after Ultrashort Electron Beam Radiation
Autor:
Tigran Harutyunyan, Anzhela Sargsyan, Lily Kalashyan, Hovhannes Igityan, Bagrat Grigoryan, Hakob Davtyan, Rouben Aroutiounian, Thomas Liehr, Galina Hovhannisyan
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6709 (2024)
Application of laser-generated electron beams in radiotherapy is a recent development. Accordingly, mechanisms of biological response to radiation damage need to be investigated. In this study, telomere length (TL) as endpoint of genetic damage was a
Externí odkaz:
https://doaj.org/article/ab120ac5ed014764a3a04551e414db6b
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 14163 (2023)
Cell-free DNA (cfDNA) in human blood serum, urine, and other body fluids recently became a commonly used diagnostic marker associated with various pathologies. This is because cfDNA enables a much higher sensitivity than standard biochemical paramete
Externí odkaz:
https://doaj.org/article/8fff236edbf0467a90fb2cf2b6978bc3
Autor:
Tigran Harutyunyan, Galina Hovhannisyan, Anzhela Sargsyan, Bagrat Grigoryan, Ahmed H. Al-Rikabi, Anja Weise, Thomas Liehr, Rouben Aroutiounian
Publikováno v:
Molecular Cytogenetics, Vol 12, Iss 1, Pp 1-6 (2019)
Abstract Background Environmental risk factors have been shown to alter DNA copy number variations (CNVs). Recently, CNVs have been described to arise after low-dose ionizing radiation in vitro and in vivo. Development of cost- and size-effective las
Externí odkaz:
https://doaj.org/article/c9348de95ca54eca9c9c47b7c2bfdf81
Autor:
Tigran Harutyunyan, Ahmed Al-Rikabi, Anzhela Sargsyan, Galina Hovhannisyan, Rouben Aroutiounian, Thomas Liehr
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 20, p 7690 (2020)
Translocation of mtDNA in the nuclear genome is an ongoing process that contributes to the development of pathological conditions in humans. However, the causal factors of this biological phenomenon in human cells are poorly studied. Here we analyzed
Externí odkaz:
https://doaj.org/article/72c59cc768bf45eb8ad560e2cbac62a2
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 19, p 4723 (2019)
DNA copy number variation (CNV) occurs due to deletion or duplication of DNA segments resulting in a different number of copies of a specific DNA-stretch on homologous chromosomes. Implications of CNVs in evolution and development of different diseas
Externí odkaz:
https://doaj.org/article/e530e84429ca4e57b7a781eb0242ceab
Publikováno v:
Cytogenetics and Molecular Cytogenetics ISBN: 9781003223658
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ebad8112af721bd83936be489805bc0
https://doi.org/10.1201/9781003223658-20
https://doi.org/10.1201/9781003223658-20
Autor:
Anzhela Sargsyan, Galina Hovhannisyan, Anna Simonyan, Marine Arakelyan, Meri Arzumanyan, Rouben Aroutiounian
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 878:503500
Application of native species as sentinels allows environmental scientists to determine real genotoxic impact of environmental pollutants. The present study aims at investigating the DNA damage in the land snail Helix lucorum as a biomarker of soil p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd9ce846626a667bd6a13d5d4693d659
https://doi.org/10.1016/j.mrgentox.2022.503500
https://doi.org/10.1016/j.mrgentox.2022.503500
Epigenetics is “the study of mitotically and/or meiotically heritable changes in gene function that cannot be explained by changes in the DNA sequence.” Thus, the same DNA sequence can lead to a variable expression in different cells. The main ep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f0d9cfa3a15d05b257f2f4bfd70590c
https://doi.org/10.1016/b978-0-12-823579-9.00008-4
https://doi.org/10.1016/b978-0-12-823579-9.00008-4
Publikováno v:
ARPHA Conference Abstracts 4: e64826
Water pollution can cause genomic instability, thereby threatening aquatic wildlife and human health․ For a correct assessment of the impact of the mixture of pollutants, chemical analysis of environmental contaminants should be simultaneously appl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc6c392bbe50812dc115deb6254cdb4d
https://aca.pensoft.net/article/64826/
https://aca.pensoft.net/article/64826/