Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Galina Bernstein"'
Autor:
Manasa Tatipalli, Vijay Kumar Siripuram, Tao Long, Diana Shuster, Galina Bernstein, Pierre Martineau, Kim A. Cook, Rodrigo Cristofoletti, Stephan Schmidt, Valvanera Vozmediano
Publikováno v:
Pharmaceutics, Vol 13, Iss 6, p 849 (2021)
Quantitative pharmacology brings important advantages in the design and conduct of pediatric clinical trials. Herein, we demonstrate the application of a model-based approach to select doses and pharmacokinetic sampling scenarios for the clinical eva
Externí odkaz:
https://doaj.org/article/b60b5d36ba56435e88197c17b4a6cbdf
Autor:
Tara L Davis, John R Walker, Valérie Campagna-Slater, Patrick J Finerty, Ragika Paramanathan, Galina Bernstein, Farrell MacKenzie, Wolfram Tempel, Hui Ouyang, Wen Hwa Lee, Elan Z Eisenmesser, Sirano Dhe-Paganon
Publikováno v:
PLoS Biology, Vol 8, Iss 7, p e1000439 (2010)
Peptidyl-prolyl isomerases catalyze the conversion between cis and trans isomers of proline. The cyclophilin family of peptidyl-prolyl isomerases is well known for being the target of the immunosuppressive drug cyclosporin, used to combat organ trans
Externí odkaz:
https://doaj.org/article/741f8b0aed584ccc95c73ca0fbd156ff
Autor:
Rodrigo Cristofoletti, Diana Shuster, Stephan Schmidt, Galina Bernstein, Pierre Martineau, Vijay Kumar Siripuram, Tao Long, Kim A Cook, Valvanera Vozmediano, Manasa Tatipalli
Publikováno v:
Pharmaceutics
Volume 13
Issue 6
Pharmaceutics, Vol 13, Iss 849, p 849 (2021)
Volume 13
Issue 6
Pharmaceutics, Vol 13, Iss 849, p 849 (2021)
Quantitative pharmacology brings important advantages in the design and conduct of pediatric clinical trials. Herein, we demonstrate the application of a model-based approach to select doses and pharmacokinetic sampling scenarios for the clinical eva
Autor:
Charles E. Inturrisi, Ottavio V. Vitolo, John Oldenhof, Catherine Mills, Kelly Davis, Michael McDonnell, Galina Bernstein, Paolo L Manfredi, Lu Wang
Publikováno v:
Journal of Clinical Psychopharmacology. 39:226-237
Purpose/background N-methyl-D-aspartate (NMDA) receptor (NMDAR) antagonists are potential agents for the treatment of several central nervous system disorders including major depressive disorder. Racemic methadone, L-methadone, and D-methadone all bi
Publikováno v:
Current Reviews in Clinical and Experimental Pharmacology. 17:3-3
Autor:
Aiping Dong, Alexander N. Plotnikov, Galina Bernstein, Anja Schuetz, Hong Wu, Peter Loppnau, Alexey Bochkarev, Tatiana Antoshenko
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 68:403-407
Becauseof this, enzymes catalyzing histone acetylation, the his-tone acetyltransferases (HATs, EC 2.3.1.48), have a majorrole in the cell fate, proliferation, and differentiation.The histone acetyltransferase GCN5 acts as a supervi-sor in the normal
Autor:
Sara Peleg, Galina Bernstein, Patrick M. Dolan, Gary H. Posner, Mehmet Kahraman, Thomas W. Kensler, Samuel S. Chuang, Uttam Saha, Sandra Sinishtaj, Bozena Korczak
Publikováno v:
Journal of Medicinal Chemistry. 47:6854-6863
A dozen 24-sulfoximine analogues of the hormone 1alpha,25-dihydroxyvitamin D(3) were prepared, differing not only at the stereogenic sulfoximine stereocenter but also at the A-ring. Although these sulfoximines were not active transcriptionally and we
Autor:
John Oldenhof, Galina Bernstein
Publikováno v:
Journal of Clinical Oncology. 35:11-11
11 Background: Planning of the dosing regimen for oncology therapeutics, based on the pre-clinical information about the monoclonal antibody, is an important step in the development of a clinical program. Accumulated material about previously develop
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