Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Galina A. Serebrennikova"'
Autor:
Marina A. Zenkova, N. G. Morozova, Evgeniya I. Chizhik, Galina A. Serebrennikova, Elena I. Ryabchikova, Mikhail A. Maslov, Dmitriy A. Rapoport
Publikováno v:
Carbohydrate Research. 345:2438-2449
Cholesterol amphiphiles containing positively charged groups (pyridinium, N-methylimidazolium, N-methylmorpholinium, and N-methylpiperidinium) linked via β-glucosyl spacer were prepared by alkylation of the corresponding bases with 6-О-mesyl-β- d
Publikováno v:
Russian Chemical Bulletin. 51:1931-1936
Cationic ether lipids containing nitrogenous heterocyclic bases as the positively charged groups were synthesized. Treatment of methylthiomethyl ethers of dialkylglycerols with bromine afforded highly reactive α-bromo ethers. These products reacted
Autor:
Tatyana V. Solomatina, Dmitry A. Cheshkov, Galina A. Serebrennikova, Mikhail A. Maslov, Olga A. Sergeeva, Nina G. Morozova
Publikováno v:
Mendeleev Communications. 21:137-139
Amino analogues of cholic acid have been synthesized by reduction of the corresponding oximes with titanium(iii) chloride in the presence of sodium cyanoborohydride.
Publikováno v:
Russian Chemical Bulletin. 49:385-401
The synthesis and biological activity of cationic lipids and cationic amphiphiles of different natures are considered. The general factors influencing the transfection efficiency are identified and summarized for various classes of compounds.
Publikováno v:
Mendeleev Communications. 19:250-252
Cholesterol-containing spermine derivatives for gene delivery were synthesised via the Fukuyama reaction.
Publikováno v:
Russian Chemical Bulletin. 48:1369-1372
A number of positively charged lipids containing pyridinium,N-methylmorpholinium,N-methylimidazolinium, 4-N,N-dimethylaminopyridinium, and 4-N,N-dimethylcyclo-hexylammonium groups linked directly to the C(3) atom of 1,2-di-O-alkylglycerols with Br−
Autor:
Tatyana V. Sokolova, Galina A. Serebrennikova, Vadim N. Sokolik, Mikhail A. Maslov, N. G. Morozova
Publikováno v:
Mendeleev Communications. 17:281-283
The synthesis of cationic amphiphiles from cholesterol methylthiomethyl ether has been carried out.
Autor:
Valentin V. Vlassov, Galina A. Serebrennikova, A. S. Alekseeva, Marina A. Zenkova, Tatyana O. Kabilova, N. G. Morozova, Ivan A. Boldyrev, Ekaterina Ivanova, Pavel A. Puchkov, Mikhail A. Maslov
Publikováno v:
Organicbiomolecular chemistry. 11(41)
Cationic liposomes are promising candidates for the delivery of various therapeutic nucleic acids. Here, we report a convenient synthesis of carbamate-type cationic lipids with various hydrophobic domains (tetradecanol, dialkylglycerol, cholesterol)
Publikováno v:
Russian Chemical Reviews. 65:537-553
Data on the structure, methods of synthesis, and applications of positively charged lipids are presented. Their likely usefulness as antitumour and antiviral agents and also as antagonists of the platelet activating factor and transfection mediators
Publikováno v:
Russian Journal of Organic Chemistry. 38:1189-1191
Syntheses of N,N,N-trimethyl[2-(3β-cholesteryloxy)syccinyloxyethyl]ammonium iodide, N,N-dimethyl-N-2-hydroxyethyl[2-(3β-cholesteryloxy)syccinyloxyethyl]ammonium iodide, and N-[(3β-cholesteryloxy)syccinyl]piperazine were performed. The compounds sy