Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Galina A. Gorneva"'
Autor:
Galina A. Gorneva, Andrzej Kochel, Nicolay I. Dodoff, Janina Kuduk-Jaworska, Dimitra Kovala-Demertzi, Maria Kubiak
Publikováno v:
Zeitschrift für Naturforschung B. 61:1110-1122
The complexes [Pt(DMSO)(GT)]·DMSO (1), [Pt(DMSO)(PT)]· 1/2 DMSO (2) and [Pd(DMSO)- (PT)] (3), where DMSO = dimethyl sulfoxide, H2GT = glyoxylic acid thiosemicarbazone and H2PT = pyruvic acid thiosemicarbazone, have been synthesized and characterize
Publikováno v:
Zeitschrift für Naturforschung C. 56:892-897
The combination of cis-diamminedichloroplatinum (II) (DDP, cisplatin) and topoisomerase II inhibitor teniposide (VM-26) has been shown to exert a synergistic effect in the clinical treatment of cancer. In this study, the combined effect of DDP and VM
Publikováno v:
Archive of Oncology, Vol 13, Iss 2, Pp 62-64 (2005)
BACKGROUND: In the light of the recent findings concerning the role of apoptosis and of tumor cell enzymes in cancer chemotherapy, the interest in pyrimidine derivatives has greatly increased. Thio- and hydrazine- pyrimidines were synthesized as pote
Publikováno v:
Arhiv za higijenu rada i toksikologiju. 63(1)
Effects of Myosmine on Antioxidative Defence in Rat LiverMyosmine [3-(1-pyrrolin-2-yl) pyridine] is an alkaloid structurally similar to nicotine, which is known to induce oxidative stress. In this study we investigated the effects of myosmine on enzy
Publikováno v:
Croatica Chemica Acta
Volume 84
Issue 3
Volume 84
Issue 3
Myosmine (3-(1-pyrrolin-2-yl)pyridine) is an alkaloid found in tobacco as well as various staple foods, fruits and vegetables. Myosmine has recently been suspected to be a tobacco-independent carcinogenic source. Using cell flow cytometry, we have ex
Autor:
Duridanova Db, Galina A. Gorneva, Svetoslav I. Taxirov, Milka S. Setchenska, Tania Y Christova
Publikováno v:
Toxicology letters. 138(3)
Changes in the activities of antioxidant enzymes superoxide dismutase, catalase (CAT), glutathione peroxidase and heme oxygenase (HO) and changes in lipid peroxidation and reduced glutathione (GSH) levels were measured in the livers of control and Le
Autor:
Daniel Kushev, Galina A. Gorneva, Nadejda Spassovska, Svetoslav I. Taxirov, Konstantin Grancharov
Publikováno v:
Biological chemistry. 380(11)
New platinum(II) complexes of cyclopentanecarboxylic acid hydrazide (cpcah) were prepared, characterized by elemental analysis, IR and 1H NMR spectra, and evaluated for in vitro cytotoxicity in Friend leukemia (FL) and A2780 ovarian tumor cells, indu
Publikováno v:
Chemotherapy. 39(1)
The inhibition of [14C]thymidine incorporation into DNA of tumor and normal tissues of L1210-leukemia-bearing mice by single doses of cis-diamminedichloroplatinum (II) (cisplatin, cis-DDP) and two newly synthesized platinum (II) complexes containing
Publikováno v:
Toxicology Letters. 196:S207
Publikováno v:
The International journal of biochemistry. 17(5)
1. 1. The cytotoxic and cytokinetic effects, and in vitro inhibition of macromolecular synthesis by cyanopyrazoles were studied using Friend leukemia and Ehrlich ascites tumor cells. 2. 2. At concentrations in the range of 2.5 mM to 50 μM analog 3(5