Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Galina A. Chernysheva"'
Autor:
Mark B. Plotnikov, Galina A. Chernysheva, Vera I. Smol’yakova, Oleg I. Aliev, Anna M. Anishchenko, Olga A. Ulyakhina, Eugene S. Trofimova, Anastasia A. Ligacheva, Nina D. Anfinogenova, Anton N. Osipenko, Anastasia R. Kovrizhina, Andrei I. Khlebnikov, Igor A. Schepetkin, Anastasia G. Drozd, Evgenii V. Plotnikov, Dmitriy N. Atochin, Mark T. Quinn
Publikováno v:
Pharmaceuticals, Vol 16, Iss 8, p 1057 (2023)
The activation of c-Jun N-terminal kinase (JNK) plays an important role in stroke outcomes. Tryptanthrin-6-oxime (TRYP-Ox) is reported to have high affinity for JNK and anti-inflammatory activity and may be of interest as a promising neuroprotective
Externí odkaz:
https://doaj.org/article/f8e06b8fec7049568f7fbab52351270e
Autor:
Mark B. Plotnikov, Galina A. Chernysheva, Vera I. Smol’yakova, Oleg I. Aliev, Tatyana I. Fomina, Lyubov A. Sandrikina, Irina V. Sukhodolo, Vera V. Ivanova, Anton N. Osipenko, Nina D. Anfinogenova, Andrei I. Khlebnikov, Dmitriy N. Atochin, Igor A. Schepetkin, Mark T. Quinn
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 714 (2023)
Activation of c-Jun N-terminal kinases (JNKs) is involved in myocardial injury, left ventricular remodeling (LV), and heart failure (HF) after myocardial infarction (MI). The aim of this research was to evaluate the effects of a selective JNK inhibit
Externí odkaz:
https://doaj.org/article/216f2644432a467b9703cf6cf31007dc
Autor:
Igor A. Schepetkin, Galina A. Chernysheva, Oleg I. Aliev, Liliya N. Kirpotina, Vera I. Smol’yakova, Anton N. Osipenko, Mark B. Plotnikov, Anastasia R. Kovrizhina, Andrei I. Khlebnikov, Evgenii V. Plotnikov, Mark T. Quinn
Publikováno v:
Biomedicines, Vol 10, Iss 9, p 2119 (2022)
The c-Jun N-terminal kinases (JNKs) regulate many physiological processes, including inflammatory responses, morphogenesis, cell proliferation, differentiation, survival, and cell death. Therefore, JNKs represent attractive targets for therapeutic in
Externí odkaz:
https://doaj.org/article/954dadc088984656bafaaa8b1ac9138c
Autor:
Mark B. Plotnikov, Galina A. Chernysheva, Vera I. Smolyakova, Oleg I. Aliev, Eugene S. Trofimova, Eugene Y. Sherstoboev, Anton N. Osipenko, Andrei I. Khlebnikov, Yana J. Anfinogenova, Igor A. Schepetkin, Dmitriy N. Atochin
Publikováno v:
Cells, Vol 9, Iss 8, p 1860 (2020)
A novel specific inhibitor of c-Jun N-terminal kinase, 11H-indeno[1,2-b]quinoxalin-11-one oxime sodium salt (IQ-1S), has a high affinity to JNK3 compared to JNK1/JNK2. The aim of this work was to study the mechanisms of neuroprotective activity of IQ
Externí odkaz:
https://doaj.org/article/3dc1138880274ce18240f8c48e38d1e9
Autor:
Mark B. Plotnikov, Galina A. Chernysheva, Oleg I. Aliev, Vera I. Smol’iakova, Tatiana I. Fomina, Anton N. Osipenko, Victoria S. Rydchenko, Yana J. Anfinogenova, Andrei I. Khlebnikov, Igor A. Schepetkin, Dmitriy N. Atochin
Publikováno v:
Molecules, Vol 24, Iss 9, p 1722 (2019)
c-Jun N-terminal kinase (JNK) is activated by various brain insults and is implicated in neuronal injury triggered by reperfusion-induced oxidative stress. Some JNK inhibitors demonstrated neuroprotective potential in various models, including cerebr
Externí odkaz:
https://doaj.org/article/d24544c34061450fbb53ff16f4a2156d
Autor:
Galina A. Chernysheva, T. M. Plotnikova, V. I. Smol’yakova, I. Yu. Chukicheva, Anton N. Osipenko, A. V. Kutchin
Publikováno v:
Bulletin of Experimental Biology and Medicine. 169:310-313
2,6-Diisobornyl-4-methylphenol (Dibornol, 10 mg/kg intragastrically daily for 5 days after myocardial ischemia/reperfusion) 1.5-fold increased rat survival during the acute post-infarction period in comparison with the control group. In survivors, Di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7afdb73c7839c36916eba41b97c34247
https://doi.org/10.1007/s10517-020-04876-9
https://doi.org/10.1007/s10517-020-04876-9
Autor:
M. Yu. Khodanovich, Marina S Kudabaeva, V. I. Smol’yakova, A. A. Kisel, Mark B. Plotnikov, Galina A. Chernysheva, Elena Krutenkova, Ya А Tyumentseva
Publikováno v:
Bulletin of Experimental Biology and Medicine. 168:224-228
This study aimed at assessing the regenerative effect of p-tyrosol in transient global cerebral ischemia modeled in adult male Wistar rats by reversible occlusion of the three major vessels originating from the aortic arch and supplying the blood to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da2469aad6a449de8e059127994a25fa
https://doi.org/10.1007/s10517-019-04679-7
https://doi.org/10.1007/s10517-019-04679-7
Autor:
Galina A. Chernysheva, Anna M. Anishchenko, Evgeny V. Buravlev, Oleg I. Aliev, A. V. Sidekhmenova, V. I. Smol’yakova, Mark B. Plotnikov, A. V. Kutchin, Irina V. Fedorova, I. A. Dvornikova, I. Yu. Chukicheva
Publikováno v:
Russian Chemical Bulletin. 68:993-999
The products of the reaction between p-cresol and camphene were isolated and characterized. Their antiradical activity and toxicity were studied. The pharmacological activity of the most active stereoisomer of 2,6-diisobornyl-4-methyl phenol in rats
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d65616c6956f7d4e0ff23ab84487d296
https://doi.org/10.1007/s11172-019-2509-0
https://doi.org/10.1007/s11172-019-2509-0
Autor:
Galina A. Chernysheva, V. I. Smol’yakova, Anton N. Osipenko, Dmitriy N. Atochin, Yana Anfinogenova, Mark B. Plotnikov, Igor A. Schepetkin, Eugene Y Sherstoboev, Andrei I. Khlebnikov, Oleg I. Aliev, Eugene S Trofimova
Publikováno v:
Cells, Vol 9, Iss 1860, p 1860 (2020)
Cells
Volume 9
Issue 8
Cells
Volume 9
Issue 8
A novel specific inhibitor of c-Jun N-terminal kinase, 11H-indeno[1,2-b]quinoxalin-11-one oxime sodium salt (IQ-1S), has a high affinity to JNK3 compared to JNK1/JNK2. The aim of this work was to study the mechanisms of neuroprotective activity of IQ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61b3889344a5ccc7e141c5b0e4620e56
https://www.mdpi.com/2073-4409/9/8/1860
https://www.mdpi.com/2073-4409/9/8/1860
Autor:
V. I. Smol’yakova, Galina A. Chernysheva, Marina S Kudabaeva, K. E. Usov, A. A. Kisel, Tatiana Anan'ina, Mark B. Plotnikov, Elena Krutenkova, M Khodanovich
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 6246, p 6246 (2020)
Volume 21
Issue 17
International Journal of Molecular Sciences, Vol 21, Iss 6246, p 6246 (2020)
Volume 21
Issue 17
(1) Background: Although myelin disruption is an integral part of ischemic brain injury, it is rarely the subject of research, particularly in animal models. This study assessed for the first time, myelin and oligodendrocyte loss in a three-vessel mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::260b04a97285e467911be7198610b262
http://europepmc.org/articles/PMC7504277
http://europepmc.org/articles/PMC7504277