Comparative effectiveness of sotrovimab versus no treatment in non-hospitalised high-risk COVID-19 patients in north west London: a retrospective cohort study.

Autor: Drysdale M; GSK, Brentford, UK myriam.g.drysdale@gsk.com., Galimov ER; Imperial College Health Partners, London, UK., Yarwood MJ; Imperial College Health Partners, London, UK., Patel V; GSK, Brentford, UK., Levick B; Evidence & Access, OPEN Health Communications LLP, London, UK., Gibbons DC; GSK, Brentford, UK., Watkins JD; Imperial College Health Partners, London, UK., Young S; Imperial College Health Partners, London, UK., Pierce BF; Imperial College Health Partners, London, UK., Lloyd EJ; GSK, Brentford, UK., Kerr W; Global Medical Affairs, GSK, Brentford, Middlesex, UK., Birch HJ; GSK, Brentford, UK., Kamalati T; Imperial College Health Partners, London, UK., Brett SJ; Department of Surgery and Cancer, Imperial College London, London, UK.

Publikováno v: BMJ open respiratory research [BMJ Open Respir Res] 2024 Apr 04; Vol. 11 (1). Date of Electronic Publication: 2024 Apr 04.

Increased fidelity of protein synthesis extends lifespan.

Autor: Martinez-Miguel VE; UCL Cancer Institute, Paul O'Gorman Building, University College London, 72 Huntley Street, London WC1E 6DD, UK., Lujan C; UCL Cancer Institute, Paul O'Gorman Building, University College London, 72 Huntley Street, London WC1E 6DD, UK., Espie-Caullet T; UCL Cancer Institute, Paul O'Gorman Building, University College London, 72 Huntley Street, London WC1E 6DD, UK., Martinez-Martinez D; MRC London Institute of Medical Sciences, Du Cane Road, London W12 0NN, UK; Institute of Clinical Sciences, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK., Moore S; MRC London Institute of Medical Sciences, Du Cane Road, London W12 0NN, UK; Institute of Clinical Sciences, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK., Backes C; MRC London Institute of Medical Sciences, Du Cane Road, London W12 0NN, UK; Institute of Clinical Sciences, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK., Gonzalez S; School of Health, Sport and Bioscience, University of East London, Water Lane, London E15 4LZ, UK., Galimov ER; MRC London Institute of Medical Sciences, Du Cane Road, London W12 0NN, UK; Institute of Clinical Sciences, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK., Brown AEX; MRC London Institute of Medical Sciences, Du Cane Road, London W12 0NN, UK; Institute of Clinical Sciences, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK., Halic M; Department of Structural Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA., Tomita K; Centre for Genome Engineering and Maintenance, College of Health, Medicine and Life Sciences, Brunel University London, London UB8 3PH, UK., Rallis C; School of Health, Sport and Bioscience, University of East London, Water Lane, London E15 4LZ, UK., von der Haar T; Kent Fungal Group, School of Biosciences, Division of Natural Sciences, University of Kent, Canterbury CT2 7NJ, UK., Cabreiro F; MRC London Institute of Medical Sciences, Du Cane Road, London W12 0NN, UK; Institute of Clinical Sciences, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Joseph Stelzmann Strasse 26, 50931 Cologne, Germany. Electronic address: f.cabreiro@imperial.ac.uk., Bjedov I; UCL Cancer Institute, Paul O'Gorman Building, University College London, 72 Huntley Street, London WC1E 6DD, UK; Department of Medical Physics and Biomedical Engineering, University College London, Malet Place Engineering Building, Gower Street, London WC1E 6BT, UK. Electronic address: i.bjedov@ucl.ac.uk.

Publikováno v: Cell metabolism [Cell Metab] 2021 Nov 02; Vol. 33 (11), pp. 2288-2300.e12. Date of Electronic Publication: 2021 Sep 14.

Mutation of daf-2 extends lifespan via tissue-specific effectors that suppress distinct life-limiting pathologies.

Autor: Zhao Y; Research Department of Genetics, Evolution and Environment, Institute of Healthy Ageing, University College London, London, UK., Zhang B; Research Department of Genetics, Evolution and Environment, Institute of Healthy Ageing, University College London, London, UK., Marcu I; Research Department of Genetics, Evolution and Environment, Institute of Healthy Ageing, University College London, London, UK., Athar F; Research Department of Genetics, Evolution and Environment, Institute of Healthy Ageing, University College London, London, UK., Wang H; Research Department of Genetics, Evolution and Environment, Institute of Healthy Ageing, University College London, London, UK., Galimov ER; Research Department of Genetics, Evolution and Environment, Institute of Healthy Ageing, University College London, London, UK., Chapman H; Research Department of Genetics, Evolution and Environment, Institute of Healthy Ageing, University College London, London, UK., Gems D; Research Department of Genetics, Evolution and Environment, Institute of Healthy Ageing, University College London, London, UK.

Publikováno v: Aging cell [Aging Cell] 2021 Mar; Vol. 20 (3), pp. e13324. Date of Electronic Publication: 2021 Feb 20.

Detecting Changes in the Caenorhabditis elegans Intestinal Environment Using an Engineered Bacterial Biosensor.

Autor: Rutter JW; Department of Cell and Developmental Biology , University College London , London WC1E 6BT , United Kingdom., Ozdemir T; Department of Cell and Developmental Biology , University College London , London WC1E 6BT , United Kingdom., Galimov ER; MRC London Institute of Medical Sciences , London W12 0NN , United Kingdom., Quintaneiro LM; Institute of Structural and Molecular Biology , University College London and Birkbeck College , London WC1E 6BT , United Kingdom., Rosa L; Department of Cell and Developmental Biology , University College London , London WC1E 6BT , United Kingdom., Thomas GM; Department of Cell and Developmental Biology , University College London , London WC1E 6BT , United Kingdom., Cabreiro F; MRC London Institute of Medical Sciences , London W12 0NN , United Kingdom.; Institute of Structural and Molecular Biology , University College London and Birkbeck College , London WC1E 6BT , United Kingdom., Barnes CP; Department of Cell and Developmental Biology , University College London , London WC1E 6BT , United Kingdom.; Department of Genetics, Evolution and Environment , University College London , London WC1E 6BT , United Kingdom.

Publikováno v: ACS synthetic biology [ACS Synth Biol] 2019 Dec 20; Vol. 8 (12), pp. 2620-2628. Date of Electronic Publication: 2019 Nov 08.

Production of YP170 Vitellogenins Promotes Intestinal Senescence in Caenorhabditis elegans.

Autor: Sornda T; Institute of Healthy Ageing, Research Department of Genetics, Evolution and Environment, University College London, UK.; Department of Biochemistry, Faculty of Medical Science, Naresuan University, Phitsanulok, Thailand., Ezcurra M; Institute of Healthy Ageing, Research Department of Genetics, Evolution and Environment, University College London, UK.; School of Biosciences, University of Kent, Canterbury, UK., Kern C; Institute of Healthy Ageing, Research Department of Genetics, Evolution and Environment, University College London, UK., Galimov ER; Institute of Healthy Ageing, Research Department of Genetics, Evolution and Environment, University College London, UK., Au C; Institute of Healthy Ageing, Research Department of Genetics, Evolution and Environment, University College London, UK., de la Guardia Y; Institute of Healthy Ageing, Research Department of Genetics, Evolution and Environment, University College London, UK.; Instituto de Investigaciones Científicas y Servicios de Alta Tecnología, Ciudad del Saber, Panama., Gems D; Institute of Healthy Ageing, Research Department of Genetics, Evolution and Environment, University College London, UK.

Publikováno v: The journals of gerontology. Series A, Biological sciences and medical sciences [J Gerontol A Biol Sci Med Sci] 2019 Jul 12; Vol. 74 (8), pp. 1180-1188.