Impact of obesity on the bioavailability of peginterferon-α2a and ribavirin and treatment outcome for chronic hepatitis C genotype 2 or 3.

Autor: Åsa Alsiö, Karolina Rembeck, Galia Askarieh, Peer Brehm Christensen, Martti Färkkilä, Nina Langeland, Mads Rauning Buhl, Court Pedersen, Kristine Mørch, Bart L Haagmans, Salmir Nasic, Johan Westin, Kristoffer Hellstrand, Gunnar Norkrans, Martin Lagging

Publikováno v: PLoS ONE, Vol 7, Iss 5, p e37521 (2012)

Having a body mass index above or equal to 30 kg/m(2) in conjunction with chronic hepatitis C virus infection is associated with non-responsiveness to treatment with interferon and ribavirin, but details regarding the mechanisms whereby obesity reduc

Externí odkaz: https://doaj.org/article/082cdb18bede4fa6bd8d0e03b0a48db8

IL28B polymorphisms, IP-10 and viral load predict virological response to therapy in chronic hepatitis C

Autor: Francesco Negro, Francesco Donato, Loredana Covolo, Giovanni Malerba, Massimo Puoti, Giovanni Raimondo, Giovanni Battista Gaeta, Giovanna Fattovich, Pierre-Yves Bochud, Martin Lagging, Galia Askarieh, Sophie Clément, Teresa Santantonio, Stéphanie Bibert, Michela Pasino, Maria Guido, Raffaele Bruno

Publikováno v: Alimentary Pharmacology & Therapeutics. 33:1162-1172

Aliment Pharmacol Ther 2011; 33: 1162–1172 Summary Background Hepatitis C virus (HCV) is a major cause of chronic liver disease, cirrhosis and hepatocellular carcinoma and the identification of the predictors of response to antiviral therapy is an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aa598ac8932ead835cf7cc142749545e
https://doi.org/10.1111/j.1365-2036.2011.04635.x

The Host Defense Peptide LL-37 Selectively Permeabilizes Apoptotic Leukocytes

Autor: Susann Teneberg, Huamei Forsman, Donald J. Davidson, Dick Hoekstra, Claes Dahlgren, Kelly L. Brown, Åse Björstad, Karin Önnheim, Karin Christenson, Hsin-Ni Li, Galia Askarieh, Johan Bylund, Olaf Maier

Publikováno v: Antimicrobial Agents and Chemotherapy, 53(3), 1027-1038. AMER SOC MICROBIOLOGY
Björstad, A, Askarieh, G, Brown, K L, Christenson, K, Forsman, H, Onnheim, K, Li, H-N, Teneberg, S, Maier, O, Hoekstra, D, Dahlgren, C, Davidson, D J & Bylund, J 2009, ' The host defense peptide LL-37 selectively permeabilizes apoptotic leukocytes ', Antimicrobial Agents and Chemotherapy, vol. 53, no. 3, pp. 1027-38 . https://doi.org/10.1128/AAC.01310-08

LL-37 is a cationic host defense peptide that is highly expressed during acute inflammation and that kills bacteria by poorly defined mechanisms, resulting in permeabilization of microbial membranes. High concentrations of LL-37 have also been report

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f3a1f33c9ed73dea34e64b921ca77e8
https://doi.org/10.1128/aac.01310-08

Impact of obesity on the bioavailability of peginterferon-α2a and ribavirin and treatment outcome for chronic hepatitis C genotype 2 or 3

Autor: Martti Färkkilä, Peer Brehm Christensen, Åsa Alsiö, Bart L. Haagmans, Kristoffer Hellstrand, Galia Askarieh, Karolina Rembeck, Kristine Mørch, Salmir Nasic, Court Pedersen, Mads Rauning Buhl, Johan Westin, Gunnar Norkrans, Martin Lagging, Nina Langeland

Publikováno v: Alsiö, Å, Rembeck, K, Askarieh, G, Christensen, P B, Färkkilä, M, Langeland, N, Buhl, M R, Pedersen, C, Mørch, K, Haagmans, B L, Nasic, S, Westin, J, Hellstrand, K, Norkrans, G & Lagging, M 2012, ' Impact of obesity on the bioavailability of peginterferon-α2a and ribavirin and treatment outcome for chronic hepatitis C genotype 2 or 3 ', P L o S One, vol. 7, no. 5, pp. e37521 . https://doi.org/10.1371/journal.pone.0037521
PLoS ONE
PLoS One (print), 7(5). Public Library of Science
PLoS ONE, Vol 7, Iss 5, p e37521 (2012)

Background and Aims: Having a body mass index above or equal to 30 kg/m2 in conjunction with chronic hepatitis C virus infection is associated with non-responsiveness to treatment with interferon and ribavirin, but details regarding the mechanisms wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c22a7b4fdb6f20b788a7932f6e949dab
https://portal.findresearcher.sdu.dk/da/publications/6c34b02b-50cf-4a7b-b30a-731a905429ba

420 INTERLEUKIN-28B POLYMORPHISMS, IP-10 AND VIRAL LOAD PREDICT VIROLOGICAL RESPONSE TO THERAPY IN CHRONIC HEPATITIS C UNDER REAL-LIFE CONDITIONS

Autor: Francesco Donato, Sophie Clément, Loredana Covolo, G. B. Gaeta, G. Raimondo, Stéphanie Bibert, Galia Askarieh, Giovanna Fattovich, Giovanni Malerba, Martin Lagging, Raffaele Bruno, Py Bochud, Maria Guido, T. Santantonio, Francesco Negro, Michela Pasino, M. Puoti

Publikováno v: Journal of Hepatology. 54:S169-S170

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f8acf799b7ff22827c2ab43de1b35ce2
https://doi.org/10.1016/s0168-8278(11)60422-4