Zobrazeno 1 - 10
of 269
pro vyhledávání: '"Galegov Ga"'
Autor:
Evgeny N. Chulakov, Galegov Ga, G. L. Levit, Dmitry A. Gruzdev, Valeria L. Andronova, Valery N. Charushin, Marina A. Ezhikova, Victor P. Krasnov, Vera V. Musiyak, Alexey Yu. Vigorov, M. I. Kodess, Olga A. Vozdvizhenskaya
Publikováno v:
European Journal of Organic Chemistry. 2019:4811-4821
Autor:
S. S. Grigorian, E. I. Isaeva, A. A. Terentyev, A. A. Balakina, V. L. Andronova, D. G. Mal’dov, Galegov Ga, A. V. Ilyichev
Publikováno v:
Problems of Virology. 63:218-223
Increased protease activity and a significant amount of granzyme B were observed in in organs of mice infected with acute herpes simplex virus HSV-1 with the introduction of Stimforte (100 or 250 µg/mouse). Thus, this drug activates killer cells, wh
Autor:
Irina D. Konstantinova, Valery N. Charushin, I. V. Fateev, Galegov Ga, Anatoly I. Miroshnikov, Alexander S. Paramonov, Maria I. Kharitonova, Svetlana K. Kotovskaya, Alexei L. Kaushin, Valeria L. Аndronova, Мaria Ya. Berzina, Konstantin V. Аntonov
Publikováno v:
Synthesis. 49:1043-1052
1-(2′-Deoxy-2′-fluoro-β- d -arabinofuranosyl)benzimidazoles containing 4,6-difluoro-, 4,5,6-trifluoro-, 5-fluoro-6-methoxy-, and 5-methoxy-4,6-difluorobenzimidazole fragments were synthesized by using purine nucleoside phosphorylase-catalyzed ch
Autor:
Roman S. Esipov, Tatyana I. Muravyova, Alexander S. Paramonov, Inessa S. Muzyka, Galina L. Levit, Irina D. Konstantinova, Barbara Z. Eletskaya, Valeria L. Andronova, Alexei L. Kayushin, Valery N. Charushin, Victor P. Krasnov, M. A. Kostromina, Anatoly I. Miroshnikov, Galegov Ga, Dmitry A. Gruzdev
Publikováno v:
Chemical biologydrug design. 93(4)
A series of ribo- and deoxyribonucleosides bearing 2-aminopurine as a nucleobase with 7,8-difluoro- 3,4-dihydro-3-methyl-2H-[1,4]benzoxazine (conjugated directly or through an aminohexanoyl spacer) was synthesized using an enzymatic transglycosylatio
Autor:
Galegov Ga, E. D. Moiseeva, S. L. Grokhovsky, A. N. Surovaya, Bazhulina Np, G. V. Gursky, V. L. Andronova, S. Yu. Lepehina
Publikováno v:
Biophysics. 61:227-232
The binding of a dimeric distamycin analog (Pt–bis–Dst) to poly[d(A–T)]poly[d(A–T)], poly(dA)poly(dT), and duplex O23 with the sequence 5’-GCCAATATATATATATTATTAGG-3’, which occurs at the origin of replication (OriS) of the herpes simplex
Publikováno v:
Doklady Biochemistry and Biophysics. 460:42-46
Autor:
Maria I. Kharitonova, Svetlana K. Kotovskaya, Alexandra O. Denisova, Irina D. Konstantinova, Valeria L. Andronova, Alexei L. Kayushin, Valery N. Charushin, Anatoly I. Miroshnikov, Galegov Ga
Publikováno v:
Bioorganicmedicinal chemistry letters. 27(11)
Using the enzymatic transglycosylation reaction β-d-ribo- and 2'-deoxyribofuranosides of 2-amino-5,6-difluorobenzimidazole nucleosides have been synthesized. 2-Amino-5,6-difluoro-benzimidazole riboside proved to exhibit a selective antiviral activit
Autor:
Skoblov IuS, V. L. Andronova, A. A. Gus’kova, D. A. Zubtsov, Skoblov MIu, Alexander Lavrov, Gol'dshteĭn Dv, Galegov Ga
Publikováno v:
Молекулярная биология. 47:602-608
It was determined the ratio of viral DNA and DNA from Vero cells using the polymerase chain reaction in real time in Vero cell lysate, infected with L2 strain of the herpes simplex virus type 1. Copy number of the virus reached a maximum after 24 hou
Autor:
N. F. Zakirova, Maxim V. Jasko, Vladimir S. Prassolov, Galegov Ga, Valeria L. Andronova, Sergey N. Kochetkov, Alexander V. Shipitsyn, M M Prokofjeva
Publikováno v:
Bioorganic & Medicinal Chemistry. 20:5802-5809
The antiviral activity against HIV and HSV and the chemical stability of ACV phosphoramidate derivatives were studied. The phosphoramidates of ACV demonstrated moderate activity. The best compound appeared to be 9-(2-hydroxymethyl)guanine phosphoromo
Autor:
S. L. Grokhovsky, A. M. Nikitin, Bazhulina Np, Galegov Ga, M. V. Golovkin, V. L. Andronova, A. N. Surovaya, Y.G. Gursky, V. S. Arkhipova, G. V. Gursky
Publikováno v:
Biophysics. 57:153-162
Data obtained show that antiviral activities of bis-linked netropsin derivatives are targeted by specific complexes formed by helicase UL9 of herpes simplex virus type 1 with viral DNA replication origins, represented by two OriS sites and one OriL s