Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Gale W. Rafter"'
Autor:
Gale W. Rafter
Publikováno v:
Journal of Inorganic Biochemistry. 38:261-264
Two drugs D-penicillamine and gold sodium thiomalate, used in the treatment of rheumatoid arthritis, removed copper(II) bound to bovine serum albumin as measured by a spectral change of the copper-albumin adduct. Utilizing the esterase activity of se
Autor:
Gale W. Rafter
Publikováno v:
Medical Hypotheses. 31:309-312
A scheme, which is selectional not instructional, is described for the molecular basis of the engram. It uses as reactants intermediates formed during the catabolism of neuronal membrane sulfhydryl proteins. It is proposed that these compounds underg
Autor:
Gale W. Rafter
Publikováno v:
Medical Hypotheses. 43:59-61
A means by which methotrexate diminishes the overproduction of leukotriene B4 by neutrophils from rheumatoid arthritic patients is described. It is postulated that neutrophil intracellular reduced glutathione is decreased by increased cellular copper
Autor:
Gale W. Rafter
Publikováno v:
Scandinavian Journal of Rheumatology. 19:385-385
(1990). Methimazole and Arthritis. Scandinavian Journal of Rheumatology: Vol. 19, No. 5, pp. 385-385.
Autor:
Gale W. Rafter, Roger S. Riley
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 381:120-127
The properties of a (Na + + K + )-dependent ATPase (ATP phosphohydrolase, EC 3.6.1.3) activator contained in leukocytic extracts was investigated. Intact polymorphonuclear leukocytes release the activator in a time- and temperature-dependent process.
Autor:
George G. Harmison, Gale W. Rafter
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Enzymology. 567:18-23
An enzyme widely distributed in rabbit tissues which catalyzes an interchange between N,N- di-dinitrophenyl- l -cystine and oxidized glutathione to form the mixed disulfide is described. d -Penicillamine disulfide can be substituted for oxidized glut
Autor:
Gale W. Rafter, James B. Blair
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 913:195-199
Homogeneous liver pyruvate kinase was reacted with different sulfhydryl reagents, which included o-iodosobenzoate, 5′,5′-dithiobis(2-nitrobenzoic acid) and N-ethylmaleimide. Activity determinations of the treated enzyme made with and without Fru(
Autor:
Gale W. Rafter, George G. Harmison
Publikováno v:
Biochemical Medicine. 13:78-82
Reduced ribonuclease devoid of enzymatic activity can undergo oxidation to give native ribonuclease with full enzymatic activity. Small amounts of E. coli lipopolysaccharide were found to interfere with the process as measured by recovered ribonuclea
Autor:
Roger S. Riley, Gale W. Rafter
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Enzymology. 410:382-388
Previous studies showed that microsomal (Na + + K + )-ATPase (ATP phosphohydrolase, EC 3.6.1.3) is activated by a proteinaeous material released by polymorphonuclear leukocytes. Investigations on the mode of action of the activator have been conducte
Autor:
Gale W. Rafter
Publikováno v:
Biochemical and Biophysical Research Communications. 126:867-872
Treatment of human IgG with pancreatic elastase gave a product of higher molecular weight than IgG. Its formation was inhibited by blocking IgG sulfhydryl groups with iodoacetamide. Incubation of the high molecular weight product with either glutathi