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pro vyhledávání: '"Gale Phillips"'
Autor:
Robert Niecestro, Jim X. Sun, Peter Lukacsko, Lawrence Friedhoff, Gale Phillips, Arnold Sterman, Michael H. Davidson, Edward J. Walters
Publikováno v:
Clinical Therapeutics. 24:112-125
Background Because lovastatin is efficiently extracted by the liver and because its administration in divided doses is associated with increased efficacy, an extended-release (ER) formulation may have the potential for a dose-sparing advantage relati
Autor:
Gale Phillips, Robert Niecestro, Michael Lamson, Peter Lukacsko, Jason Shen, Lawrence Friedhoff
Publikováno v:
Biopharmaceutics & Drug Disposition. 23:143-149
The purpose of this study was to evaluate pharmacokinetics and dose proportionality of lovastatin extended-release dosage form (ER-lovastatin) in the dosage levels of 10, 20 and 40 mg in 9 healthy male subjects. Each subject was randomized to receive