Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Galanin receptor 3"'
Autor:
Hua Du, Wei-Dong Chen, Xiaobo Nie, Wang Qun, Yang Li, Binbin Cui, Shuangyu Lv, Xiaomei Zhang, Yanjie Yang, Yuchen Zhou, Yan-Dong Wang, Ye Wenling
Publikováno v:
The American Journal of Pathology. 189:886-899
Spexin/NPQ is a novel highly conserved neuropeptide. It has a widespread expression in the periphery and central nervous system. However, the effects of central spexin on acute inflammatory pain are still unknown. This study explored the mechanisms a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a7163e5484b5a2323c09a4937df70a0
https://doi.org/10.1016/j.ajpath.2018.12.009
https://doi.org/10.1016/j.ajpath.2018.12.009
Autor:
Ludwik K. Malendowicz, Marta Szyszka, Marianna Tyczewska, Paulina Milecka, Piotr Celichowski, Karol Jopek, Marcin Rucinski, Hanna Komarowska
Publikováno v:
Advances in Clinical and Experimental Medicine. 28:737-746
Background Galanin-like peptide (Galp) and alarin (Ala) are 2 new members of the galanin peptide family. Galanin (Gal), the "parental" peptide of the entire family, is known to regulate numerous physiological processes, including energy and osmotic h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f57c09fa4bc20b98a79572d2db2249bb
https://doi.org/10.17219/acem/95039
https://doi.org/10.17219/acem/95039
Autor:
Dawid Szczepankiewicz, Paweł Kołodziejski, Maciej Sassek, Krzysztof W. Nowak, Ewa Pruszyńska-Oszmałek
Publikováno v:
General and comparative endocrinology. 299
The present study aimed to characterize the role of spexin (SPX) in maintaining glucose and lipid homeostasis in vivo in rats with diet-induced obesity. The in vitro effect of spexin on metabolic and endocrine functions of adipocytes isolated from ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44c4579e1e6183c8365016f520b317f8
https://pubmed.ncbi.nlm.nih.gov/32950584
https://pubmed.ncbi.nlm.nih.gov/32950584
Autor:
Barbara Kofler, Andrew J Lawrence, Karlene J Scheller, Susanne M. Brunner, Bradley J. Turner, Shannyn G. Genders, Maarten van den Buuse, Emily J. Jaehne, Elvan Djouma
Publikováno v:
Addiction Biology. 24:886-897
Galanin is a neuropeptide which mediates its effects via three G-protein coupled receptors (GAL1-3 ). Administration of a GAL3 antagonist reduces alcohol self-administration in animal models while allelic variation in the GAL3 gene has been associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a700299b43dece350f7d8f19b90bff7
https://doi.org/10.1111/adb.12641
https://doi.org/10.1111/adb.12641
Autor:
Elvan Djouma, Matthew W. Hale, Spencer J. Williams, Adam J. Lawther, Sigrid Limburg, Kira-Elise Wilson, Andrew J Lawrence, Melissa K Duggan
Publikováno v:
Journal of Psychopharmacology. 32:911-921
Introduction: This study aimed to investigate the effects of the galanin-3 receptor antagonist, SNAP 37889, on c-Fos protein expression after cue-induced reinstatement of alcohol-seeking in the brains of alcohol-preferring rats. Methods: Eighteen alc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3514095e961352c9b0b860d835d408c4
https://doi.org/10.1177/0269881118780015
https://doi.org/10.1177/0269881118780015
Autor:
Herbert A. Reitsamer, Roland Lang, Felix Locker, Andreas Koller, Barbara Kofler, Silvia Vidali, David Schwarzenbacher, Julia Stockinger, Sabine Ebner, Barbara S. Holub, Susanne M. Brunner, Andrea Trost
Publikováno v:
Journal of Investigative Dermatology. 138:199-207
The neuropeptide galanin is distributed in the central and peripheral nervous systems and in non-neuronal peripheral organs, including the skin. Galanin acts via three G protein-coupled receptors which, except galanin receptor 1, are expressed in var
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc3fdba9376ffbd48ad7ca9ce8217759
https://doi.org/10.1016/j.jid.2017.08.015
https://doi.org/10.1016/j.jid.2017.08.015
Autor:
Denise D. Belsham, Andy Tran
Publikováno v:
Journal of the Endocrine Society
Spexin (SPX) is a recently discovered peptide that binds to galanin receptors 2 (GalR2) and 3 (GalR3). Emerging evidence implicates SPX as a modulator of satiety and energy balance as circulating SPX levels are dysregulated in obesity. However, it is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d71bb9920ef149f834d6b21c69bdfe83
https://doi.org/10.1210/js.2019-sun-482
https://doi.org/10.1210/js.2019-sun-482
Publikováno v:
European journal of immunologyReferences. 50(1)
Mast cells are generally classified into two phenotypically distinct populations: mucosal-type mast cells (MMCs) and connective tissue-type mast cells (CTMCs). However, the molecular basis determining the different characteristics of the mast cell su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c1c1c252c909a0816c82cc99cb7610f
https://pubmed.ncbi.nlm.nih.gov/31706262
https://pubmed.ncbi.nlm.nih.gov/31706262
Publikováno v:
Molecular and Cellular Endocrinology. 518:110991
The function of the gonadotropin-releasing hormone (GnRH) neuron is critical to maintain reproductive function and a significant decrease in GnRH can lead to disorders affecting fertility, including hypogonadotropic hypogonadism. Spexin (SPX) is a no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47caaba74cc1118dd3dd5a8d3ca99cee
https://doi.org/10.1016/j.mce.2020.110991
https://doi.org/10.1016/j.mce.2020.110991
Autor:
Barbara Kofler, Martin Jakab, Hubert Kerschbaum, Andreas Lang, Kamil Önder, M. Beyreis, Andreas Koller, Felix Locker, Bernhard Brodowicz, Barbara S. Holub, Ognjen Velickovic, Rodolfo Bianchini, Raphaela Rid
Publikováno v:
Neuropeptides. 56:83-88
Galanin and its receptors (GAL1, GAL2, GAL3) modulate a range of neuronal, immune and vascular activities. In vivo administration of SNAP 37889 (1-phenyl-3-[[3-(trifluoromethyl)phenyl]imino]-1H-indol-2-one), a potent small non-peptidergic antagonist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2376cc788bd9a7dafa965198ae25cb9f
https://doi.org/10.1016/j.npep.2015.12.003
https://doi.org/10.1016/j.npep.2015.12.003