High-potency ligands for DREADD imaging and activation in rodents and monkeys.

Autor: Bonaventura J; Biobehavioral Imaging and Molecular Neuropsychopharmacology Unit, National Institute on Drug Abuse Intramural Research Program, Baltimore, MD, 21224, USA., Eldridge MAG; Laboratory of Neuropsychology, National Institute of Mental Health Intramural Research Program, Bethesda, MD, 20892, USA., Hu F; Department of Radiology Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA., Gomez JL; Biobehavioral Imaging and Molecular Neuropsychopharmacology Unit, National Institute on Drug Abuse Intramural Research Program, Baltimore, MD, 21224, USA., Sanchez-Soto M; Molecular Neuropharmacology Section, National Institute of Neurological Disorders and Stroke Intramural Research Program, Bethesda, MD, 20814, USA., Abramyan AM; Computational Chemistry and Molecular Biophysics Unit, National Institute on Drug Abuse Intramural Research Program, Baltimore, MD, 21224, USA., Lam S; Biobehavioral Imaging and Molecular Neuropsychopharmacology Unit, National Institute on Drug Abuse Intramural Research Program, Baltimore, MD, 21224, USA., Boehm MA; Biobehavioral Imaging and Molecular Neuropsychopharmacology Unit, National Institute on Drug Abuse Intramural Research Program, Baltimore, MD, 21224, USA., Ruiz C; Department of Neurobiology & Behavior, University of California, Irvine, CA, 92697, USA., Farrell MR; Department of Neurobiology & Behavior, University of California, Irvine, CA, 92697, USA., Moreno A; Department of Molecular Biology and Genetics, Dandrite, Aarhus University, 8000 Aarhus C, Aarhus, Denmark., Galal Faress IM; Department of Molecular Biology and Genetics, Dandrite, Aarhus University, 8000 Aarhus C, Aarhus, Denmark., Andersen N; Department of Molecular Biology and Genetics, Dandrite, Aarhus University, 8000 Aarhus C, Aarhus, Denmark., Lin JY; School of Medicine, College of Health and Medicine, University of Tasmania, Tasmania, TAS, 7000, Australia., Moaddel R; Laboratory of Clinical Investigation, National Institute on Aging Intramural Research Program, Baltimore, MD, 21224, USA., Morris PJ; National Center for Advancing Translational Sciences, Rockville, MD, 20850, USA., Shi L; Computational Chemistry and Molecular Biophysics Unit, National Institute on Drug Abuse Intramural Research Program, Baltimore, MD, 21224, USA., Sibley DR; Molecular Neuropharmacology Section, National Institute of Neurological Disorders and Stroke Intramural Research Program, Bethesda, MD, 20814, USA., Mahler SV; Department of Neurobiology & Behavior, University of California, Irvine, CA, 92697, USA., Nabavi S; Department of Molecular Biology and Genetics, Dandrite, Aarhus University, 8000 Aarhus C, Aarhus, Denmark., Pomper MG; Department of Radiology Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA., Bonci A; Synaptic Plasticity Section, National Institute on Drug Abuse Intramural Research Program, Baltimore, MD, 21224, USA., Horti AG; Department of Radiology Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA. ahorti1@jhmi.edu., Richmond BJ; Laboratory of Neuropsychology, National Institute of Mental Health Intramural Research Program, Bethesda, MD, 20892, USA. barryrichmond@mail.nih.gov., Michaelides M; Biobehavioral Imaging and Molecular Neuropsychopharmacology Unit, National Institute on Drug Abuse Intramural Research Program, Baltimore, MD, 21224, USA. mike.michaelides@nih.gov.; Department of Psychiatry, Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA. mike.michaelides@nih.gov.

Publikováno v: Nature communications [Nat Commun] 2019 Oct 11; Vol. 10 (1), pp. 4627. Date of Electronic Publication: 2019 Oct 11.