Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Gal Shafirstein"'
Autor:
Batoul Dhaini, Philippe Arnoux, Joël Daouk, François Lux, Olivier Tillement, Agnès Hagège, Tayssir Hamieh, Gal Shafirstein, Céline Frochot
Publikováno v:
Pharmaceuticals, Vol 17, Iss 8, p 1033 (2024)
Photodynamic therapy is an accepted therapy cancer treatment. Its advantages encourage researchers to delve deeper. The use of nanoparticles in PDT has several advantages including the passive targeting of cancer cells. The aim of this article is to
Externí odkaz:
https://doaj.org/article/24280ddf3c4345eea9e76f514cc0babf
Autor:
Nathaniel M. Ivanick, MD, Emily R. Oakley, PhD, Rajesh Kunadharaju, MD, Craig Brackett, PhD, David A. Bellnier, PhD, Lawrence M. Tworek, BS, Sergei N. Kurenov, MS, Sandra O. Gollnick, PhD, Alan D. Hutson, PhD, Theresa M. Busch, PhD, Gal Shafirstein, DSc
Publikováno v:
JTO Clinical and Research Reports, Vol 3, Iss 10, Pp 100372- (2022)
Objective: Patients with inoperable extrabronchial or endobronchial tumors who are not candidates for curative radiotherapy have dire prognoses with no effective long-term treatment options. To reveal that our computer-optimized interstitial photodyn
Externí odkaz:
https://doaj.org/article/f654ca181d41421095fc18945a599bfe
Publikováno v:
mSphere, Vol 5, Iss 4 (2020)
ABSTRACT Moraxella catarrhalis, Streptococcus pneumoniae, and nontypeable Haemophilus influenzae (NTHi) are ubiquitous upper respiratory opportunistic pathogens. Together, these three microbes are the most common causative bacterial agents of pediatr
Externí odkaz:
https://doaj.org/article/70c44095722142e3abd9111d70f5ac33
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Otitis media (OM) is a prevalent pediatric infection characterized by painful inflammation of the middle ear. There are more than 700 million cases of OM diagnosed globally each year, with 50% of affected children under 5 years of age. Further, OM is
Externí odkaz:
https://doaj.org/article/82099ada9c8540c0b8d0ab1790082f1d
Publikováno v:
World Journal of Otorhinolaryngology-Head and Neck Surgery, Vol 2, Iss 2, Pp 126-129 (2016)
Photodynamic therapy has shown promise in the treatment of early head and neck squamous cell carcinoma (SCC). In photodynamic therapy (PDT), a light sensitive drug (photosensitizer) and visible light cause cancer cell death by the creation of singlet
Externí odkaz:
https://doaj.org/article/1e79123513c3418a8226bf629fa1c543
Autor:
Sarah Chamberlain, Houston D. Cole, John Roque, David Bellnier, Sherri A. McFarland, Gal Shafirstein
Publikováno v:
Pharmaceuticals, Vol 13, Iss 7, p 137 (2020)
Intra-operative photodynamic therapy (IO-PDT) in combination with surgery for the treatment of non-small cell lung cancer and malignant pleural mesothelioma has shown promise in improving overall survival in patients. Here, we developed a PDT platfor
Externí odkaz:
https://doaj.org/article/4a0dfcef42294335ba5359d4e9fc7168
Autor:
Shaila Mudambi, Megan Fitzgerald, Paula Pera, Deschana Washington, Sarah Chamberlain, Eszter Fidrus, Csaba Hegedűs, Eva Remenyik, Gal Shafirstein, David Bellnier, Gyorgy Paragh
Publikováno v:
Photodermatology, photoimmunologyphotomedicineREFERENCES.
Lysine-specific histone demethylase 1 (KDM1A/LSD1) regulates multiple cellular functions, including cellular proliferation, differentiation, and DNA repair. KDM1A is overexpressed in squamous cell carcinoma of the skin and inhibition of KDM1A can sup
Autor:
Emily Oakley, Evgueni Parilov, Karl Beeson, Mary Potasek, Nathaniel Ivanick, Lawrence Tworek, Alan Hutson, Gal Shafirstein
Publikováno v:
Cancers; Volume 15; Issue 9; Pages: 2636
There are no effective treatments for patients with extrinsic malignant central airway obstruction (MCAO). In a recent clinical study, we demonstrated that interstitial photodynamic therapy (I-PDT) is a safe and potentially effective treatment for pa
Autor:
Emily Oakley, Sarah Chamberlain, Nathaniel Ivanick, Alan Hutson, Theresa Busch, Gal Shafirstein
Publikováno v:
Cancer Research. 83:2423-2423
Background: Patients with extrabronchial tumors that induce malignant central airway obstruction (MCAO) face dire prognoses with significant morbidity and 1-7 months overall survival. These tumors are inoperable. High-dose curative radiotherapy is as
Autor:
Emily Oakley, Minhyung Kim, Sanjana Ghosh, Hilliard Kutscher, Jonathan Lovell, Leslie Curtin, Sandra Sexton, Alan Hutson, Gal Shafirstein
Publikováno v:
Cancer Research. 83:2420-2420
Background Patients with hepatocellular carcinoma (HCC) have a poor prognosis with a 5-year survival rate of only 35%. Patients with locally advanced HCC (single or multinodal tumors >3 cm) may not be candidates for curative treatments such as surgic