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Human inherited PD-L1 deficiency is clinically and immunologically less severe than PD-1 deficiency.
Autor:
Johnson MB; Clinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter , Exeter, UK., Ogishi M; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University , New York, NY, USA., Domingo-Vila C; Department of Immunobiology, School of Immunology and Microbial Sciences, Kings College London, London, UK., De Franco E; Clinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter , Exeter, UK., Wakeling MN; Clinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter , Exeter, UK., Imane Z; Faculty of Medicine and Pharmacy, Mohammed 5 University of Rabat , Rabat, Morocco., Resnick B; National Institute for Health and Care Research Exeter Clinical Research Facility, Royal Devon University Healthcare NHS Foundation Trust , Exeter, UK., Williams E; Department of Immunobiology, School of Immunology and Microbial Sciences, Kings College London, London, UK., Galão RP; Department of Infectious Diseases, School of Immunobiology and Microbial Sciences, Kings College London, London, UK., Caswell R; Clinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter , Exeter, UK., Russ-Silsby J; Clinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter , Exeter, UK., Seeleuthner Y; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163 , Paris, France.; Imagine Institute, Paris Cité University , Paris, France., Rinchai D; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University , New York, NY, USA., Fagniez I; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University , New York, NY, USA., Benson B; Center for Systems Immunology, Benaroya Research Institute , Seattle, WA, USA., Dufort MJ; Center for Systems Immunology, Benaroya Research Institute , Seattle, WA, USA., Speake C; Center for Interventional Immunology, Benaroya Research Institute , Seattle, WA, USA., Smithmyer ME; Center for Interventional Immunology, Benaroya Research Institute , Seattle, WA, USA., Hudson M; Clinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter , Exeter, UK.; National Institute for Health and Care Research Exeter Clinical Research Facility, Royal Devon University Healthcare NHS Foundation Trust , Exeter, UK., Dobbs R; Clinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter , Exeter, UK.; National Institute for Health and Care Research Exeter Clinical Research Facility, Royal Devon University Healthcare NHS Foundation Trust , Exeter, UK., Quandt Z; Endocrine Division, Department of Medicine, University of California San Francisco, San Francisco, CA, USA.; Diabetes Center, University of California San Francisco , San Francisco, CA, USA., Hattersley AT; Clinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter , Exeter, UK., Zhang P; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University , New York, NY, USA., Boisson-Dupuis S; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University , New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163 , Paris, France.; Imagine Institute, Paris Cité University , Paris, France., Anderson MS; Endocrine Division, Department of Medicine, University of California San Francisco, San Francisco, CA, USA.; Diabetes Center, University of California San Francisco , San Francisco, CA, USA., Casanova JL; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University , New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163 , Paris, France.; Imagine Institute, Paris Cité University , Paris, France.; Department of Pediatrics, Necker Hospital for Sick Children, Paris, France.; Howard Hughes Medical Institute , New York, NY, USA., Tree TI; Department of Immunobiology, School of Immunology and Microbial Sciences, Kings College London, London, UK., Oram RA; Clinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter , Exeter, UK.
Publikováno v:
The Journal of experimental medicine [J Exp Med] 2024 Jun 03; Vol. 221 (6). Date of Electronic Publication: 2024 Apr 18.
Autor:
Galão RP; Department of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, United Kingdom., Wilson H; Department of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, United Kingdom., Schierhorn KL; Department of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, United Kingdom., Debeljak F; Department of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, United Kingdom., Bodmer BS; Institute for Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Greifswald, Germany., Goldhill D; Section of Virology, Department of Medicine, Imperial College London, London, United Kingdom., Hoenen T; Institute for Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Greifswald, Germany., Wilson SJ; MRC Centre for Virus Research, University of Glasgow, United Kingdom., Swanson CM; Department of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, United Kingdom., Neil SJD; Department of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, United Kingdom.
Publikováno v:
PLoS pathogens [PLoS Pathog] 2022 May 09; Vol. 18 (5), pp. e1010530. Date of Electronic Publication: 2022 May 09 (Print Publication: 2022).
Autor:
Pickering S; Department of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, London, UK., Batra R; Centre for Clinical Infection and Diagnostics Research, Department of Infectious Diseases, Guy's and St Thomas' NHS Foundation Trust, London, UK., Merrick B; Centre for Clinical Infection and Diagnostics Research, Department of Infectious Diseases, Guy's and St Thomas' NHS Foundation Trust, London, UK., Snell LB; Centre for Clinical Infection and Diagnostics Research, Department of Infectious Diseases, Guy's and St Thomas' NHS Foundation Trust, London, UK., Nebbia G; Centre for Clinical Infection and Diagnostics Research, Department of Infectious Diseases, Guy's and St Thomas' NHS Foundation Trust, London, UK., Douthwaite S; Centre for Clinical Infection and Diagnostics Research, Department of Infectious Diseases, Guy's and St Thomas' NHS Foundation Trust, London, UK., Reid F; School of Population Health and Environmental Sciences, King's College London, London, UK., Patel A; Centre for Clinical Infection and Diagnostics Research, Department of Infectious Diseases, Guy's and St Thomas' NHS Foundation Trust, London, UK., Kia Ik MT; Centre for Clinical Infection and Diagnostics Research, Department of Infectious Diseases, Guy's and St Thomas' NHS Foundation Trust, London, UK., Patel B; Centre for Clinical Infection and Diagnostics Research, Department of Infectious Diseases, Guy's and St Thomas' NHS Foundation Trust, London, UK., Charalampous T; Centre for Clinical Infection and Diagnostics Research, Department of Infectious Diseases, Guy's and St Thomas' NHS Foundation Trust, London, UK., Alcolea-Medina A; Centre for Clinical Infection and Diagnostics Research, Department of Infectious Diseases, Guy's and St Thomas' NHS Foundation Trust, London, UK.; Viapath Group, Guy's and St Thomas' NHS Foundation Trust, London, UK., Lista MJ; Department of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, London, UK., Cliff PR; Viapath Group, Guy's and St Thomas' NHS Foundation Trust, London, UK., Cunningham E; Viapath Group, Guy's and St Thomas' NHS Foundation Trust, London, UK., Mullen J; Viapath Group, Guy's and St Thomas' NHS Foundation Trust, London, UK., Doores KJ; Department of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, London, UK., Edgeworth JD; Department of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, London, UK.; Centre for Clinical Infection and Diagnostics Research, Department of Infectious Diseases, Guy's and St Thomas' NHS Foundation Trust, London, UK., Malim MH; Department of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, London, UK., Neil SJD; Department of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, London, UK., Galão RP; Department of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, London, UK.
Publikováno v:
The Lancet. Microbe [Lancet Microbe] 2021 Sep; Vol. 2 (9), pp. e461-e471. Date of Electronic Publication: 2021 Jun 30.
Autor:
Koller G; Centre for Host Microbiome Interactions, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London, SE1 9RT, United Kingdom., Morrell AP; Centre for Oral, Clinical & Translational Sciences, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London SE1 9RT, United Kingdom., Galão RP; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, London SE1 9RT, United Kingdom., Pickering S; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, London SE1 9RT, United Kingdom., MacMahon E; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, London SE1 9RT, United Kingdom.; Guy's and St Thomas' NHS Foundation Trust, London SE1 9RT, United Kingdom., Johnson J; Guy's and St Thomas' NHS Foundation Trust, London SE1 9RT, United Kingdom., Ignatyev K; Diamond Light Source, Harwell OX11 0DE, United Kingdom., Neil SJD; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, London SE1 9RT, United Kingdom., Elsharkawy S; Centre for Oral, Clinical & Translational Sciences, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London SE1 9RT, United Kingdom., Fleck R; Centre for Ultrastructural Imaging, King's College London, London SE1 9RT, United Kingdom., Machado PMP; Centre for Ultrastructural Imaging, King's College London, London SE1 9RT, United Kingdom., Addison O; Centre for Oral, Clinical & Translational Sciences, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London SE1 9RT, United Kingdom.
Publikováno v:
ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2021 Jun 09; Vol. 13 (22), pp. 25694-25700. Date of Electronic Publication: 2021 May 28.
Autor:
Pickering S; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, London, United Kingdom., Betancor G; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, London, United Kingdom., Galão RP; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, London, United Kingdom., Merrick B; Centre for Clinical Infection and Diagnostics Research, Department of Infectious Diseases, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom., Signell AW; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, London, United Kingdom., Wilson HD; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, London, United Kingdom., Kia Ik MT; Centre for Clinical Infection and Diagnostics Research, Department of Infectious Diseases, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom., Seow J; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, London, United Kingdom., Graham C; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, London, United Kingdom., Acors S; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, London, United Kingdom., Kouphou N; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, London, United Kingdom., Steel KJA; Centre for Inflammation Biology and Cancer Immunology (CIBCI), Dept of Inflammation Biology, School of Immunology & Microbial Sciences, King's College London, London, United Kingdom., Hemmings O; Department of Immunobiology, School of Immunology and Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom., Patel A; Centre for Clinical Infection and Diagnostics Research, Department of Infectious Diseases, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom., Nebbia G; Centre for Clinical Infection and Diagnostics Research, Department of Infectious Diseases, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom., Douthwaite S; Centre for Clinical Infection and Diagnostics Research, Department of Infectious Diseases, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom., O'Connell L; Centre for Clinical Infection and Diagnostics Research, Department of Infectious Diseases, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom., Luptak J; MRC Laboratory of Molecular Biology, Cambridge, United Kingdom., McCoy LE; Division of Infection and Immunity, University College London (UCL), London, United Kingdom., Brouwer P; Department of Medical Microbiology, Amsterdam UMC, University of Amsterdam, Amsterdam Infection & Immunity Institute, Amsterdam, the Netherlands., van Gils MJ; Department of Medical Microbiology, Amsterdam UMC, University of Amsterdam, Amsterdam Infection & Immunity Institute, Amsterdam, the Netherlands., Sanders RW; Department of Medical Microbiology, Amsterdam UMC, University of Amsterdam, Amsterdam Infection & Immunity Institute, Amsterdam, the Netherlands., Martinez Nunez R; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, London, United Kingdom., Bisnauthsing K; Centre for Clinical Infection and Diagnostics Research, Department of Infectious Diseases, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom., O'Hara G; Centre for Clinical Infection and Diagnostics Research, Department of Infectious Diseases, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom., MacMahon E; Centre for Clinical Infection and Diagnostics Research, Department of Infectious Diseases, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom., Batra R; Centre for Clinical Infection and Diagnostics Research, Department of Infectious Diseases, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom., Malim MH; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, London, United Kingdom., Neil SJD; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, London, United Kingdom., Doores KJ; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, London, United Kingdom., Edgeworth JD; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, London, United Kingdom.; Centre for Clinical Infection and Diagnostics Research, Department of Infectious Diseases, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Publikováno v:
PLoS pathogens [PLoS Pathog] 2020 Sep 24; Vol. 16 (9), pp. e1008817. Date of Electronic Publication: 2020 Sep 24 (Print Publication: 2020).
Autor:
Shaw AM; Department of Bioscience, College of Life and Environmental Sciences, University of Exeter, Stocker Road, Exeter, EX4 4QD, UK. andrew.m.shaw@exeter.ac.uk and Attomarker Ltd, Innovation Centre, University of Exeter, Rennes Drive, Exeter, EX4 4RN, UK., Hyde C; Exeter Test Group, College of Medicine and Health, University of Exeter, St Luke's Campus, Heavitree Road, Exeter, EX1 2LU, UK., Merrick B; Centre for Clinical Infection and Diagnostics Research, Department of Infectious Diseases, Guy's and St Thomas' NHS Foundation Trust, London SE1 7EH, UK. Jonathan.Edgeworth@gstt.nhs.uk., James-Pemberton P; Department of Bioscience, College of Life and Environmental Sciences, University of Exeter, Stocker Road, Exeter, EX4 4QD, UK. andrew.m.shaw@exeter.ac.uk and Attomarker Ltd, Innovation Centre, University of Exeter, Rennes Drive, Exeter, EX4 4RN, UK., Squires BK; Attomarker Ltd, Innovation Centre, University of Exeter, Rennes Drive, Exeter, EX4 4RN, UK., Olkhov RV; Department of Bioscience, College of Life and Environmental Sciences, University of Exeter, Stocker Road, Exeter, EX4 4QD, UK. andrew.m.shaw@exeter.ac.uk and Attomarker Ltd, Innovation Centre, University of Exeter, Rennes Drive, Exeter, EX4 4RN, UK., Batra R; Centre for Clinical Infection and Diagnostics Research, Department of Infectious Diseases, Guy's and St Thomas' NHS Foundation Trust, London SE1 7EH, UK. Jonathan.Edgeworth@gstt.nhs.uk., Patel A; Centre for Clinical Infection and Diagnostics Research, Department of Infectious Diseases, Guy's and St Thomas' NHS Foundation Trust, London SE1 7EH, UK. Jonathan.Edgeworth@gstt.nhs.uk., Bisnauthsing K; Centre for Clinical Infection and Diagnostics Research, Department of Infectious Diseases, Guy's and St Thomas' NHS Foundation Trust, London SE1 7EH, UK. Jonathan.Edgeworth@gstt.nhs.uk., Nebbia G; Centre for Clinical Infection and Diagnostics Research, Department of Infectious Diseases, Guy's and St Thomas' NHS Foundation Trust, London SE1 7EH, UK. Jonathan.Edgeworth@gstt.nhs.uk., MacMahon E; Centre for Clinical Infection and Diagnostics Research, Department of Infectious Diseases, Guy's and St Thomas' NHS Foundation Trust, London SE1 7EH, UK. Jonathan.Edgeworth@gstt.nhs.uk., Douthwaite S; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, UK., Malim M; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, UK., Neil S; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, UK., Martinez Nunez R; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, UK., Doores K; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, UK., Mark TKI; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, UK., Signell AW; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, UK., Betancor G; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, UK., Wilson HD; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, UK., Galão RP; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, UK., Pickering S; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, UK., Edgeworth JD; Centre for Clinical Infection and Diagnostics Research, Department of Infectious Diseases, Guy's and St Thomas' NHS Foundation Trust, London SE1 7EH, UK. Jonathan.Edgeworth@gstt.nhs.uk and Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, UK.
Publikováno v:
The Analyst [Analyst] 2020 Aug 21; Vol. 145 (16), pp. 5638-5646. Date of Electronic Publication: 2020 Jul 08.
Autor:
Galão RP; Department of Infectious Disease, King's College London School of Medicine, Guy's Hospital, London SE1 9RT, UK., Pickering S; Department of Infectious Disease, King's College London School of Medicine, Guy's Hospital, London SE1 9RT, UK., Curnock R; School of Biochemistry, Faculty of Medical and Veterinary Sciences, University of Bristol, Bristol BS8 1TD, UK., Neil SJ; Department of Infectious Disease, King's College London School of Medicine, Guy's Hospital, London SE1 9RT, UK. Electronic address: stuart.neil@kcl.ac.uk.
Publikováno v:
Cell host & microbe [Cell Host Microbe] 2014 Sep 10; Vol. 16 (3), pp. 291-303.
Autor:
Goujon C; Department of Infectious Diseases, King's College London, 2nd Floor, Borough Wing, Guy's Hospital, London Bridge, London SE1 9RT, UK., Schaller T, Galão RP, Amie SM, Kim B, Olivieri K, Neil SJ, Malim MH
Publikováno v:
Retrovirology [Retrovirology] 2013 Feb 25; Vol. 10, pp. 23. Date of Electronic Publication: 2013 Feb 25.
Autor:
Galão RP; Department of Infectious Disease, King's College London School of Medicine, Guy's Hospital, London SE1 9RT, UK., Le Tortorec A, Pickering S, Kueck T, Neil SJ
Publikováno v:
Cell host & microbe [Cell Host Microbe] 2012 Nov 15; Vol. 12 (5), pp. 633-44.