Zobrazeno 1 - 10
of 216
pro vyhledávání: '"Gaku TSUJI"'
Publikováno v:
Journal of Cutaneous Immunology and Allergy, Vol 7 (2024)
Background: Tapinarof is a nonsteroidal, topical, aryl hydrocarbon receptor agonist. Tapinarof has been shown to be efficacious and have acceptable safety profile in the treatment of atopic dermatitis (AD).Objective: We sought to evaluate the improve
Externí odkaz:
https://doaj.org/article/ca3f5f18158f423495f802d4db1d2eb1
Autor:
Makiko Kido-Nakahara, Daisuke Onozuka, Kenji Izuhara, Hidehisa Saeki, Satoshi Nunomura, Motoi Takenaka, Mai Matsumoto, Yoko Kataoka, Rai Fujimoto, Sakae Kaneko, Eishin Morita, Akio Tanaka, Ryo Saito, Tatsuro Okano, Tomomitsu Miyagaki, Natsuko Aoki, Kimiko Nakajima, Susumu Ichiyama, Kyoko Tonomura, Yukinobu Nakagawa, Risa Tamagawa-Mineoka, Koji Masuda, Takuya Takeichi, Masashi Akiyama, Yozo Ishiuji, Michie Katsuta, Yuki Kinoshita, Chiharu Tateishi, Aya Yamamoto, Akimichi Morita, Haruna Matsuda-Hirose, Yutaka Hatano, Hiroshi Kawasaki, Ayano Fukushima-Nomura, Mamitaro Ohtsuki, Koji Kamiya, Yudai Kabata, Riichiro Abe, Hiroshi Mitsui, Tatsuyoshi Kawamura, Gaku Tsuji, Masutaka Furue, Norito Katoh, Takeshi Nakahara
Publikováno v:
Allergology International, Vol 73, Iss 2, Pp 332-334 (2024)
Externí odkaz:
https://doaj.org/article/70272fe7bce744dab7bd11fc8d371fcb
Autor:
Itsuki Takei, Takamichi Ito, Maho Murata, Taketoshi Ide, Gaku Tsuji, Makiko Kido-Nakahara, Takeshi Nakahara
Publikováno v:
Journal of Plastic and Reconstructive Surgery, Vol 3, Iss 1, Pp 26-28 (2024)
Burn, a common injury in daily life, is a potential risk factor for severe sequelae in people, particularly children. Preventing unexpected burn injuries is of the utmost importance. This study examined the current status of pediatric burns in our in
Externí odkaz:
https://doaj.org/article/08f96429b40d46abbb49c0c97cb32d4a
Autor:
Gaku Tsuji, Ayako Yumine, Koji Kawamura, Masaki Takemura, Makiko Kido-Nakahara, Kazuhiko Yamamura, Takeshi Nakahara
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 14, p 7910 (2024)
Difamilast, a phosphodiesterase 4 (PDE4) inhibitor, has been shown to be effective in the treatment of atopic dermatitis (AD), although the mechanism involved remains unclear. Since IL-33 plays an important role in the pathogenesis of AD, we investig
Externí odkaz:
https://doaj.org/article/e0f0935e82eb4a0285c713c3d6e2e06f
Publikováno v:
Antioxidants, Vol 13, Iss 6, p 732 (2024)
Semaphorin 3A (SEMA3A), a nerve-repellent factor produced by keratinocytes, has an inhibitory effect on nerve extension to the epidermis. Epidermal innervation is involved in pruritus in inflammatory skin diseases such as atopic dermatitis (AD) and d
Externí odkaz:
https://doaj.org/article/ca3ba97fdfb841808ca379bf314553bd
Autor:
Takeshi Nakahara, MD, PhD, Daisuke Onozuka, PhD, Satoshi Nunomura, PhD, Hidehisa Saeki, MD, PhD, Motoi Takenaka, MD, PhD, Mai Matsumoto, MD, PhD, Yoko Kataoka, MD, Rai Fujimoto, MD, PhD, Sakae Kaneko, MD, PhD, Eishin Morita, MD, PhD, Akio Tanaka, MD, PhD, Ryo Saito, MD, PhD, Tatsuro Okano, MD, PhD, Tomomitsu Miyagaki, MD, PhD, Natsuko Aoki, MD, PhD, Kimiko Nakajima, MD, PhD, Susumu Ichiyama, MD, PhD, Makiko Kido-Nakahara, MD, PhD, Kyoko Tonomura, MD, PhD, Yukinobu Nakagawa, MD, PhD, Risa Tamagawa-Mineoka, MD, PhD, Koji Masuda, MD, PhD, Takuya Takeichi, MD, PhD, Masashi Akiyama, MD, PhD, Yozo Ishiuji, MD, PhD, Michie Katsuta, MD, PhD, Yuki Kinoshita, MD, PhD, Chiharu Tateishi, MD, PhD, Aya Yamamoto, MD, PhD, Akimichi Morita, MD, PhD, Haruna Matsuda-Hirose, MD, PhD, Yutaka Hatano, MD, PhD, Hiroshi Kawasaki, MD, PhD, Ayano Fukushima-Nomura, MD, Mamitaro Ohtsuki, MD, PhD, Koji Kamiya, MD, PhD, Yudai Kabata, MD, PhD, Riichiro Abe, MD, PhD, Hiroshi Mitsui, MD, PhD, Tatsuyoshi Kawamura, MD, PhD, Gaku Tsuji, MD, PhD, Norito Katoh, MD, PhD, Masutaka Furue, MD, PhD, Kenji Izuhara, MD, PhD
Publikováno v:
Journal of Allergy and Clinical Immunology: Global, Vol 3, Iss 1, Pp 100175- (2024)
Background: To develop precision medicine for atopic dermatitis (AD), it is critical to establish relevant biomarkers. However, the characteristics of various biomarkers have not been fully understood. We previously carried out the Biomarkers to Pred
Externí odkaz:
https://doaj.org/article/e11f03b3ae004428bb4cca14383d8c63
Autor:
Yuka Tanaka, Takamichi Ito, Yumiko Kaku-Ito, Keiko Tanegashima, Gaku Tsuji, Makiko Kido-Nakahara, Yoshinao Oda, Takeshi Nakahara
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-12 (2023)
Abstract Acral melanoma (AM) is a rare, life-threatening skin cancer. Since AM bears unique features, existing therapies for other types of malignant melanomas have limited effects and the establishment of effective treatments for AM is strongly desi
Externí odkaz:
https://doaj.org/article/9816ca1f0c1a4e54a294fee6efc94870
Autor:
Gaku Tsuji, Kazuhiko Yamamura, Koji Kawamura, Makiko Kido-Nakahara, Takamichi Ito, Takeshi Nakahara
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14633 (2023)
Interleukin (IL)-33 and IL-37 have been identified as novel cytokines involved in various inflammatory diseases. However, their specific roles remain largely unknown. Recent studies have shown that IL-33, which triggers inflammation, and IL-37, which
Externí odkaz:
https://doaj.org/article/f924ff44d0874355a13a1f45beab9426
Autor:
Gaku Tsuji, Kazuhiko Yamamura, Koji Kawamura, Makiko Kido-Nakahara, Takamichi Ito, Takeshi Nakahara
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1303 (2023)
Atopic dermatitis (AD) is a chronic inflammatory skin disease that significantly impacts quality of life. The pathogenesis of AD is a complex combination of skin barrier dysfunction, type II immune response, and pruritus. Progress in the understandin
Externí odkaz:
https://doaj.org/article/72a05b34c3134096ae319252c6a54be6
Publikováno v:
Cell Death and Disease, Vol 12, Iss 6, Pp 1-11 (2021)
Abstract Neurofibromatosis type 1 is an autosomal dominant genetic disorder caused by mutation in the neurofibromin 1 (NF1) gene. Its hallmarks are cutaneous findings including neurofibromas, benign peripheral nerve sheath tumors. We analyzed the col
Externí odkaz:
https://doaj.org/article/533521085f8748f2aabc7cacfec5f125