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Akademický článek

Reduced Abundance of Phocaeicola in Mucosa-associated Microbiota Is Associated with Distal Colorectal Cancer Metastases Possibly through an Altered Local Immune Environment

Autor: Gaku Ota, Ryo Inoue, Akira Saito, Yoshihiko Kono, Joji Kitayama, Naohiro Sata, Hisanaga Horie

Publikováno v: Journal of the Anus, Rectum and Colon, Vol 8, Iss 3, Pp 235-245 (2024)

Objectives: The aim of this study was to identify the microbiota whose decrease in tumor area was associated with the metastatic process of distal colorectal cancer (CRC). Methods: Twenty-eight consecutive patients with distal CRC undergoing surgical

Externí odkaz: https://doaj.org/article/6579df500bec4ebb941bec44db6959d3

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Akademický článek

The effect of staple height and rectal-wall thickness on anastomotic leakage after laparoscopic low anterior resection

Autor: Daishi Naoi, Hisanaga Horie, Ai Sadatomo, Koji Koinuma, Gaku Ota, Kenichi Oshiro, Makiko Tahara, Katsusuke Mori, Homare Ito, Yoshiyuki Inoue, Yuko Homma, Toshiki Mimura, Alan Kawarai Lefor, Naohiro Sata

Publikováno v: Asian Journal of Surgery, Vol 46, Iss 4, Pp 1577-1582 (2023)

Background: The aim of this study was to evaluate the effect of staple height and rectal wall thickness on the development of an anastomotic leak after laparoscopic low anterior resection performed with the double stapling technique. Methods: One hun

Externí odkaz: https://doaj.org/article/2528a6fd0de844028dbdd9a975b05255

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Akademický článek

Flow cytometry detection of cell type-specific expression of programmed death receptor ligand-1 (PD-L1) in colorectal cancer specimens

Autor: Akira Saito, Mineyuki Tojo, Yuko Kumagai, Hideyuki Ohzawa, Hironori Yamaguchi, Hideyo Miyato, Ai Sadatomo, Daishi Naoi, Gaku Ota, Koji Koinuma, Hisanaga Horie, Alan Kawarai Lefor, Naohiro Sata, Joji Kitayama

Publikováno v: Heliyon, Vol 7, Iss 1, Pp e05880- (2021)

Aim: PD-1/PD-L1 blockade therapy is now widely used for the treatment of advanced malignancies. Although PD-L1 is known to be expressed by various host cells as well as tumor cells, the role of PD-L1 on non-malignant cells and its clinical significan

Externí odkaz: https://doaj.org/article/b735ea30c5e041da976d4be6f412a970

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Metachronous Krukenberg tumor from adenocarcinoma in a Meckel’s diverticulum: a case report

Autor: Gaku Ota, Naohiro Sata, Hisanaga Horie, Koji Koinuma, Tomonori Yano, Ryotaro Sakio, Makiko Tahara, Homare Ito, Alan Kawarai Lefor, Hironori Yamamoto

Publikováno v: Journal of Surgical Case Reports

Adenocarcinoma in a Meckel’s diverticulum is rare and difficult to diagnose preoperatively. We report the first case of a metachronous Krukenberg tumor from adenocarcinoma in a Meckel’s diverticulum. A 45-year-old woman was admitted for recurrent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05e8962e54d2df83c7cc8e003f180f97
http://europepmc.org/articles/PMC8407034

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Flow cytometry detection of cell type-specific expression of programmed death receptor ligand-1 (PD-L1) in colorectal cancer specimens

Autor: Hideyo Miyato, Daishi Naoi, Ai Sadatomo, Hideyuki Ohzawa, Alan Kawarai Lefor, Hironori Yamaguchi, Mineyuki Tojo, Yuko Kumagai, Akira Saito, Gaku Ota, Joji Kitayama, Hisanaga Horie, Koji Koinuma, Naohiro Sata

Publikováno v: Heliyon, Vol 7, Iss 1, Pp e05880-(2021)
Heliyon

Aim PD-1/PD-L1 blockade therapy is now widely used for the treatment of advanced malignancies. Although PD-L1 is known to be expressed by various host cells as well as tumor cells, the role of PD-L1 on non-malignant cells and its clinical significanc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42f832af963da7bba83628f865837067
http://www.sciencedirect.com/science/article/pii/S2405844020327225

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Intestinal mucosa staple line integrity and anastomotic leak pressure after healing in a porcine model

Autor: Hisanaga Horie, Naohiro Sata, Yuko Kumagai, Noriyoshi Fukushima, Koji Koinuma, Ai Sadatomo, Shuji Hishikawa, Daishi Naoi, Yuji Kaneda, Mineyuki Tojo, Alan Kawarai Lefor, Yoshiyuki Inoue, Gaku Ota

Publikováno v: Surgery today. 51(10)

The aim of this study was to evaluate both the intestinal mucosa staple line integrity and anastomotic leak pressure after healing in a porcine survival model.We used two suture models using two different size staples (incomplete mucosal closure mode

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::439e439ac3a7aba635881b9e4c97ec85
https://pubmed.ncbi.nlm.nih.gov/33743053

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