Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Gajendra S. Naika"'
Autor:
Edgar A. Hodge, Gajendra S. Naika, Sally M. Kephart, Adam Nguyen, Richard Zhu, Mark A. Benhaim, Wenjin Guo, John P. Moore, Shiu-Lok Hu, Rogier W. Sanders, Kelly K. Lee
Publikováno v:
iScience, Vol 25, Iss 6, Pp 104449- (2022)
Summary: The envelope glycoprotein (Env) is the sole target for neutralizing antibodies against HIV and the most rapidly evolving, variable part of the virus. High-resolution structures of Env trimers captured in the pre-fusion, closed conformation h
Externí odkaz:
https://doaj.org/article/935242cc58c844479c66c9ed25cfbdb2
Autor:
Meghan Zuck, Myriam Bouchlaka, Huyen Dinh, Kevin Green, Francisco Zapata, Ramya Chandrasekaran, Tatyana Pisarenko, Lauren Loh, Gajendra S. Naika, Meilyn Sylvestre, Jacob Heit, Raymond Fox, Darbie Whitman, Tom Graddis, Kamal D. Puri, Peter Probst
Publikováno v:
Cancer Research. 83:6376-6376
Background: One cause for the failure of checkpoint inhibitors is the immunosuppressive nature of the tumor microenvironment. LILRB1 (ILT2) and LILRB2 (ILT4) are ITIM-containing inhibitory receptors that recognize HLA Class 1 and nonclassical ligands
Autor:
Matthieu Rousseau, Gajendra S Naika, Jean Perron, Frederic Jacques, Michael H Gelb, Eric Boilard
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126204 (2015)
The thymus is a primary lymphoid organ, home of maturation and selection of thymocytes for generation of functional T-cells. Multiple factors are involved throughout the different stages of the maturation process to tightly regulate T-cell production
Externí odkaz:
https://doaj.org/article/9f521ea7340c4163a5c498ed3d1a16ae
Autor:
Anthony Kicic, Teal S. Hallstrand, James G. Bollinger, M.H. Gelb, G. Lambeau, James D. Nolin, Ying Lai, W.R. Henderson, Gajendra S. Naika, Herbert Luke Ogden, Stephen M. Stick, Charles W. Frevert, William A. Altemeier
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 55:825-836
Secreted phospholipase A2s (sPLA2s) regulate eicosanoid formation and have been implicated in asthma. Although sPLA2s function as enzymes, some of the sPLA2s bind with high affinity to a C-type lectin receptor, called PLA2R1, which has functions in b
Autor:
Anne-Claire, Duchez, Luc H, Boudreau, Gajendra S, Naika, Matthieu, Rousseau, Nathalie, Cloutier, Tania, Levesque, Michael H, Gelb, Eric, Boilard
Publikováno v:
Prostaglandinsother lipid mediators. 143
Phospholipase A
Autor:
Charles W. Frevert, Ryan C. Murphy, Anne M. Manicone, Farideh Ghomashchi, Teal S. Hallstrand, Michael H. Gelb, Herbert Luke Ogden, Adrian M. Piliponsky, Dowon An, Ying Lai, James D. Nolin, William A. Altemeier, Gajendra S. Naika, Gail M. Gauvreau
Publikováno v:
JCI insight. 2(21)
Phospholipase A2 (PLA2) enzymes regulate the formation of eicosanoids and lysophospholipids that contribute to allergic airway inflammation. Secreted PLA2 group X (sPLA2-X) was recently found to be increased in the airways of asthmatics and is highly
Autor:
James G. Bollinger, Denis Soulet, Gérard Lambeau, Helga Guderley, Michael H. Gelb, Steve Lacroix, Hind Hamzeh-Cognasse, Nathalie Cloutier, Luc H. Boudreau, Louis Thibault, John W. Semple, Nicolas Martin, Anne Claire Duchez, Eric Boilard, Alexandre Paré, Richard W. Farndale, Olivier Garraud, Gajendra S. Naika, Marc Pouliot, Matthieu Rousseau, Fabrice Cognasse, Cynthia Laflamme, Tania Lévesque, Geneviève Marcoux, Peter A. Nigrovic
Publikováno v:
Blood. 124:2173-2183
Mitochondrial DNA (mtDNA) is a highly potent inflammatory trigger and is reportedly found outside the cells in blood in various pathologies. Platelets are abundant in blood where they promote hemostasis. Although lacking a nucleus, platelets contain
Autor:
James D, Nolin, H Luke, Ogden, Ying, Lai, William A, Altemeier, Charles W, Frevert, James G, Bollinger, Gajendra S, Naika, Anthony, Kicic, Stephen M, Stick, Gerard, Lambeau, William R, Henderson, Michael H, Gelb, Teal S, Hallstrand
Publikováno v:
American journal of respiratory cell and molecular biology. 55(6)
Secreted phospholipase A2s (sPLA2s) regulate eicosanoid formation and have been implicated in asthma. Although sPLA2s function as enzymes, some of the sPLA2s bind with high affinity to a C-type lectin receptor, called PLA2R1, which has functions in b
Autor:
Purnima Kaul Tiku, Gajendra S. Naika
Publikováno v:
Carbohydrate Research. 345:1627-1631
Low concentrations of urea and GuHCl (2 M) enhanced the activity of endoglucanase (EC 3.1.2.4) from Aspergillus aculeatus by 2.3- and 1.9-fold, respectively. The K m values for controls, in the presence of 2 M urea and GuHCl, were found to be 2.4 ±
Autor:
Raifish E Mendoza-Villarroel, Clémence Belleannée, Anne-Claire Duchez, Emmanuelle Rollet-Labelle, Marc Pouliot, Benoit Laffont, Patrice E. Poubelle, Isabelle Allaeys, Nathalie Cloutier, Matthieu Rousseau, Patrick Provost, James G. Bollinger, Gajendra S. Naika, Gérard Lambeau, Luc H. Boudreau, Jacques J. Tremblay, Tania Lévesque, Denis Soulet, Michael H. Gelb, Eric Boilard
Platelets are anucleated blood elements highly potent at generating extracellular vesicles (EVs) called microparticles (MPs). Whereas EVs are accepted as an important means of intercellular communication, the mechanisms underlying platelet MP interna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b737e61651da2c618164019e13e3ff7a
https://europepmc.org/articles/PMC4500271/
https://europepmc.org/articles/PMC4500271/