Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Gaixiu Zhang"'
Autor:
Yan Liang, Cai Zhang, Haiyan Wei, Hongwei Du, Gaixiu Zhang, Yu Yang, Hua Zhang, Haihong Gong, Pin Li, Fuying Song, Zhuangjian Xu, Ruoyi He, Weidong Zhou, Heng Zheng, Li Sun, Xiaoping Luo
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
ObjectivesTo investigate the pharmacokinetics (PK) and pharmacodynamics (PD) of Y-shape branched PEGylated recombinant human growth hormone (YPEG-rhGH) and evaluate its short-term efficacy and safety in children with growth hormone deficiency (GHD).M
Externí odkaz:
https://doaj.org/article/8a6a8eddae5f4ba8ba948021aaca1193
Autor:
Jinna Yuan, Junfen Fu, Haiyan Wei, Gaixiu Zhang, Yanfeng Xiao, Hongwei Du, Wei Gu, Yanhong Li, Linqi Chen, Feihong Luo, Yan Zhong, Haihong Gong
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
BackgroundTo evaluate the safety and efficacy of daily somatropin (Jintropin®), a recombinant human growth hormone, in prepubertal children with ISS in China.MethodsThis study was a multicenter, randomized, controlled, open-label, phase 3 study. All
Externí odkaz:
https://doaj.org/article/58bc929782b64b1dbcc81eacb6a9c17d
Publikováno v:
Journal of Nanoscience and Nanotechnology. 13:6940-6947
Au-Pd alloy nanowires with controllable morphology and composition are useful sensing materials for chemical and biological sensors. This report describes the preparation of such Au-Pd alloy nanowires from an aqueous solution by alternating current (
Publikováno v:
Journal of Crystal Growth. 334:181-188
Au–Pt dentritic nanowires (DNWs) bridging a pair of 10–40 μm spacing electrodes were successfully self-assembled from the corresponding ions solution via deposition of an alternating current (AC). The morphology and the composition of Au–Pt DN
Publikováno v:
International Journal of Molecular Medicine. 26(5):667-671
The survival of motor neuron (SMN) protein forms a multiprotein complex (SMN complex) with Gemin proteins. The complex is known to play a crucial role in RNA metabolism. Several lines of evidence show that SMN is phosphorylated at serine and/or threo
Autor:
Nathalie Guffon, Yusuke Aoki, Marie-Odile Rolland, Gaixiu Zhang, Toshiyuki Fukao, Marie-Therese Zabot, Naomi Kondo
Publikováno v:
Molecular Genetics and Metabolism. 92:375-378
A tandem repeat of exons 8 and 9 was identified in the cDNA for mitochondrial acetoacetyl-CoA thiolase (T2) in a typical T2 deficient patient. Routine mutation analysis using PCR at the genomic level had failed to identify any mutations. Alu element-
Autor:
Naomi Kondo, Toshiyuki Fukao, Takahide Teramoto, Hideo Kaneko, Takahiro Arai, Gaixiu Zhang, Hideo Sugie, Yusuke Aoki
Publikováno v:
Molecular Genetics and Metabolism. 92:179-182
X-linked liver glycogenosis (XLG) is one of the most common glycogen storage diseases. We present the first case of a large PHKA2 gene deletion from intron 19 to intron 26 in an XLG patient. An aberrant cDNA with skipping of exons 20-26 was detected.
Autor:
Naomi Kondo, Satomi Sakurai, Toshiyuki Fukao, Ronald J.A. Wanders, Keitaro Yamada, Jos P.N. Ruiter, Gaixiu Zhang
Publikováno v:
Molecular genetics and metabolism, 90(3), 291-297. Academic Press Inc.
Succinyl-CoA:3-ketoacid CoA transferase (SCOT, EC 2.8.3.5) is the key enzyme for ketone body utilization. Hereditary SCOT deficiency (MIM 245050) causes episodes of severe ketoacidosis. We identified a homozygous point mutation (c.671G>A) , which is
Autor:
Keitaro Yamada, Rik K. Wierenga, Shoji Yano, Gaixiu Zhang, Ronald J.A. Wanders, Naomi Kondo, Toshiyuki Fukao, Michael K. Gibson, Peter H. Robinson, Antti M. Haapalainen, Franco Lilliu, Grant A. Mitchell, Satomi Sakurai
Publikováno v:
Molecular genetics and metabolism, 90(4), 370-378. Academic Press Inc.
Mitochondrial acetoacetyl-CoA thiolase (T2) deficiency is an inborn error of metabolism that affects isoleucine catabolism and ketone body metabolism. We identified 7 novel and 2 previously reported mutations in six T2-deficient patients. Transient e
Publikováno v:
Molecular medicine reports. 3(2)
In ketone body metabolism, hepatocyte-specific silencing of the succinyl-CoA:3-ketoacid CoA transferase (SCOT) gene appears to be physiologically important to avoid a futile cycle in the liver, whereas the SCOT gene is expressed in extrahepatic tissu